CA2146448A1 - 3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions - Google Patents

3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions

Info

Publication number
CA2146448A1
CA2146448A1 CA002146448A CA2146448A CA2146448A1 CA 2146448 A1 CA2146448 A1 CA 2146448A1 CA 002146448 A CA002146448 A CA 002146448A CA 2146448 A CA2146448 A CA 2146448A CA 2146448 A1 CA2146448 A1 CA 2146448A1
Authority
CA
Canada
Prior art keywords
pharmaceutical preparation
chloro
weight
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002146448A
Other languages
English (en)
French (fr)
Inventor
Imran Ahmed
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2146448A1 publication Critical patent/CA2146448A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
CA002146448A 1992-10-07 1993-09-02 3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions Abandoned CA2146448A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95793092A 1992-10-07 1992-10-07
US957,930 1992-10-07

Publications (1)

Publication Number Publication Date
CA2146448A1 true CA2146448A1 (en) 1994-04-14

Family

ID=25500362

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002146448A Abandoned CA2146448A1 (en) 1992-10-07 1993-09-02 3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions

Country Status (21)

Country Link
EP (1) EP0662831A1 (ru)
JP (1) JP2721042B2 (ru)
KR (1) KR950703338A (ru)
CN (1) CN1089138A (ru)
AU (1) AU676200B2 (ru)
BR (1) BR9307182A (ru)
CA (1) CA2146448A1 (ru)
CZ (1) CZ282702B6 (ru)
EG (1) EG20289A (ru)
FI (1) FI934387A (ru)
HU (1) HUT68533A (ru)
IL (1) IL107122A (ru)
MX (1) MX9306222A (ru)
MY (1) MY109680A (ru)
NO (1) NO951350L (ru)
NZ (1) NZ256164A (ru)
PL (1) PL174170B1 (ru)
RU (1) RU2119353C1 (ru)
TW (1) TW438798B (ru)
WO (1) WO1994007488A1 (ru)
ZA (1) ZA937405B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2076106B1 (es) * 1993-08-26 1996-06-16 Pfizer Composiciones farmaceuticas a base de 2-oxindol-1-carboxamidas 3-sustituidas
WO1995031979A1 (en) * 1994-05-19 1995-11-30 R.P. Scherer International Corporation Solutions of aryl or heteroaryl substituted alkanoic acids in lipophilic solvents and soft gelatin capsules containing such solutions
UA42739C2 (ru) * 1995-04-24 2001-11-15 Пфайзер Інк. Способ ингибирования фотораспада фармацевтически активных соединений, таблетка и капсула, их содержащие
AU5340298A (en) * 1996-12-27 1998-07-31 Takeda Chemical Industries Ltd. Stabilized tricyclic compound
JP5869764B2 (ja) * 2011-01-07 2016-02-24 中日本カプセル 株式会社 カプセル充填用組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
US5008283A (en) * 1990-03-19 1991-04-16 Pfizer Inc. Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
DE69216642T2 (de) * 1992-01-13 1997-05-07 Pfizer Verfahren zur herstellung von tabletten mit hoher festigkeit

Also Published As

Publication number Publication date
NO951350L (no) 1995-06-06
FI934387A (fi) 1994-04-08
EP0662831A1 (en) 1995-07-19
EG20289A (en) 1998-07-30
TW438798B (en) 2001-06-07
PL174170B1 (pl) 1998-06-30
AU4839293A (en) 1994-04-26
HUT68533A (en) 1995-04-27
CZ282702B6 (cs) 1997-09-17
MX9306222A (es) 1994-04-29
WO1994007488A1 (en) 1994-04-14
KR950703338A (ko) 1995-09-20
HU9302821D0 (en) 1993-12-28
NZ256164A (en) 1997-03-24
PL308307A1 (en) 1995-07-24
FI934387A0 (fi) 1993-10-06
ZA937405B (en) 1995-04-06
CZ87895A3 (en) 1995-10-18
BR9307182A (pt) 1999-03-30
NO951350D0 (no) 1995-04-06
IL107122A0 (en) 1993-12-28
IL107122A (en) 1998-08-16
CN1089138A (zh) 1994-07-13
MY109680A (en) 1997-04-30
AU676200B2 (en) 1997-03-06
RU2119353C1 (ru) 1998-09-27
JPH07507809A (ja) 1995-08-31
JP2721042B2 (ja) 1998-03-04

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued