CA2135767A1 - System for controlled release of antiarrhythmic agents - Google Patents

System for controlled release of antiarrhythmic agents

Info

Publication number
CA2135767A1
CA2135767A1 CA002135767A CA2135767A CA2135767A1 CA 2135767 A1 CA2135767 A1 CA 2135767A1 CA 002135767 A CA002135767 A CA 002135767A CA 2135767 A CA2135767 A CA 2135767A CA 2135767 A1 CA2135767 A1 CA 2135767A1
Authority
CA
Canada
Prior art keywords
controlling device
cardiac rhythm
arrangement
antiarrhythmic agent
heart
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002135767A
Other languages
English (en)
French (fr)
Inventor
Robert J. Levy
Amnon Sintov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2135767A1 publication Critical patent/CA2135767A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3629—Heart stimulators in combination with non-electric therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002135767A 1993-03-15 1994-03-15 System for controlled release of antiarrhythmic agents Abandoned CA2135767A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3330793A 1993-03-15 1993-03-15
US08/033,307 1993-03-15

Publications (1)

Publication Number Publication Date
CA2135767A1 true CA2135767A1 (en) 1994-09-29

Family

ID=21869658

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002135767A Abandoned CA2135767A1 (en) 1993-03-15 1994-03-15 System for controlled release of antiarrhythmic agents

Country Status (7)

Country Link
EP (1) EP0644756A4 (de)
JP (1) JPH07509735A (de)
KR (1) KR950702101A (de)
AU (1) AU6446794A (de)
CA (1) CA2135767A1 (de)
NZ (1) NZ263685A (de)
WO (1) WO1994021237A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6322548B1 (en) 1995-05-10 2001-11-27 Eclipse Surgical Technologies Delivery catheter system for heart chamber
US6524298B1 (en) 1995-06-07 2003-02-25 Cardiogenesis Corporation Therapeutic and diagnostic agent delivery
US6775574B1 (en) * 1997-11-07 2004-08-10 Medtronic, Inc. Method and system for myocardial infarction repair
US7031775B2 (en) 1997-11-07 2006-04-18 Medtronic, Inc. Method and system for myocardial infarction repair
ES2169980B1 (es) 1999-12-17 2003-11-01 Lipotec Sa Microcapsulas para la liberacion prolongada de farmacos.
US6613025B1 (en) 2000-05-25 2003-09-02 Scimed Life Systems, Inc. Method and apparatus for diagnostic and therapeutic agent delivery
US6572534B1 (en) 2000-09-14 2003-06-03 Abiomed, Inc. System and method for implanting a cardiac wrap
US6846296B1 (en) 2000-09-14 2005-01-25 Abiomed, Inc. Apparatus and method for detachably securing a device to a natural heart
US6540659B1 (en) 2000-11-28 2003-04-01 Abiomed, Inc. Cardiac assistance systems having bi-directional pumping elements
US6616596B1 (en) 2000-11-28 2003-09-09 Abiomed, Inc. Cardiac assistance systems having multiple layers of inflatable elements
US6602182B1 (en) 2000-11-28 2003-08-05 Abiomed, Inc. Cardiac assistance systems having multiple fluid plenums
US6547716B1 (en) 2000-11-28 2003-04-15 Abiomed, Inc. Passive cardiac restraint systems having multiple layers of inflatable elements
JP2004518664A (ja) 2000-12-27 2004-06-24 ジェンザイム・コーポレーション 抗不整脈剤の調節された放出
US20030009145A1 (en) * 2001-03-23 2003-01-09 Struijker-Boudier Harry A.J. Delivery of drugs from sustained release devices implanted in myocardial tissue or in the pericardial space
US20020188327A1 (en) * 2001-04-26 2002-12-12 Chester Struble Drug delivery for treatment of cardiac arrhythmia
US6626821B1 (en) 2001-05-22 2003-09-30 Abiomed, Inc. Flow-balanced cardiac wrap
EP1451306A1 (de) * 2001-11-06 2004-09-01 Medtronic, Inc. Verfahren und system zur operativen versorgung nach myokardinfarkt
US6968226B2 (en) 2002-01-30 2005-11-22 Medtronic, Inc. Method and system for terminating an atrial arrhythmia
AU2003248751A1 (en) * 2002-06-28 2004-01-19 Genzyme Corporation Controlled release of anti-arrhythmic agents
US7917208B2 (en) 2002-10-04 2011-03-29 Microchips, Inc. Medical device for controlled drug delivery and cardiac monitoring and/or stimulation
KR20080073328A (ko) * 2005-11-16 2008-08-08 토카이 유니버시티 에듀케이셔널시스템 약제 방출 제어 조성물 및 약제 방출성 의료 기구

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374669A (en) * 1975-05-09 1983-02-22 Mac Gregor David C Cardiovascular prosthetic devices and implants with porous systems
US4506680A (en) * 1983-03-17 1985-03-26 Medtronic, Inc. Drug dispensing body implantable lead
US5090422A (en) * 1990-04-19 1992-02-25 Cardiac Pacemakers, Inc. Implantable electrode pouch
US5087243A (en) * 1990-06-18 1992-02-11 Boaz Avitall Myocardial iontophoresis
US5154182A (en) * 1991-02-15 1992-10-13 Siemens Pacesetter, Inc. Drug or steroid releasing patch electrode for an implantable arrhythmia treatment system
DE69210395T2 (de) * 1991-04-05 1997-01-09 Medtronic Inc Erfassungssystem mit subkutanen mehrfachelektroden

Also Published As

Publication number Publication date
WO1994021237A1 (en) 1994-09-29
KR950702101A (ko) 1995-06-19
EP0644756A1 (de) 1995-03-29
EP0644756A4 (de) 1996-02-28
NZ263685A (en) 1997-08-22
AU6446794A (en) 1994-10-11
JPH07509735A (ja) 1995-10-26

Similar Documents

Publication Publication Date Title
CA2135767A1 (en) System for controlled release of antiarrhythmic agents
US5387419A (en) System for controlled release of antiarrhythmic agents
US6168801B1 (en) Controlled release drug delivery
US10363411B2 (en) Microelectrode and multiple microelectrodes
US7689291B2 (en) Lead with fibrous matrix coating and methods related thereto
US5154182A (en) Drug or steroid releasing patch electrode for an implantable arrhythmia treatment system
US6461644B1 (en) Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods
US8911427B2 (en) Therapeutic agent reservoir delivery system
US5345933A (en) Implantable medical device with a protected medication layer
US20020035388A1 (en) Temporary medical electrical lead having biodegradable electrode mounting pad loaded with therapeutic drug
US20080132922A1 (en) Mesh Pouches for Implantable Medical Devices
US20100168808A1 (en) Preventing biofilm formation on implantable medical devices
JP2009507577A (ja) 医療用リードのための薬剤溶出被覆およびそのための方法
EP1098675A2 (de) Verfahren und gerät zur biventrikulären zweikammerstimulation und -defibrillation
JP2001513369A (ja) 改善された生物適合性を有する無菌の生物侵食性の移植デバイスおよび方法
JP2010508915A (ja) 埋込型医療機器のためのメッシュパウチ
US8527067B2 (en) Tapered drug-eluting collar for a medical electrical lead
US20090099612A1 (en) Electrical conductor having a bioerodible coating
JPH0686829A (ja) 薬剤を長期搬送するための方法およびデバイス
Labhasetwar et al. Iontophoresis for modulation of cardiac drug delivery in dogs.
WO2014137454A1 (en) Methods and compositions to inhibit the assemblage of microbial cells irreversibly associated with surfaces of medical devices
WO2011031301A2 (en) Intrapericardial delivery of periostin
AU2013200515C1 (en) Mesh pouches for implantable medical devices
Levy et al. Controlled release implant dosage forms for cardiac arrhythmias: Review and perspectives
TWI323667B (en) Implantable and sealable device for unidirectional delivery of therapeutic agents to tissues

Legal Events

Date Code Title Description
FZDE Dead