CA2132708A1 - Immunoessais de fluorescence, utilisant des colorants fluorescents sans agregation ni liaison serique - Google Patents
Immunoessais de fluorescence, utilisant des colorants fluorescents sans agregation ni liaison seriqueInfo
- Publication number
- CA2132708A1 CA2132708A1 CA002132708A CA2132708A CA2132708A1 CA 2132708 A1 CA2132708 A1 CA 2132708A1 CA 002132708 A CA002132708 A CA 002132708A CA 2132708 A CA2132708 A CA 2132708A CA 2132708 A1 CA2132708 A1 CA 2132708A1
- Authority
- CA
- Canada
- Prior art keywords
- aggregation
- fluorescent dyes
- fluorescence immunoassays
- serum binding
- dyes free
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000003018 immunoassay Methods 0.000 title abstract 3
- 210000002966 serum Anatomy 0.000 title abstract 3
- 238000004220 aggregation Methods 0.000 title abstract 2
- 230000002776 aggregation Effects 0.000 title abstract 2
- 239000007850 fluorescent dye Substances 0.000 title abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 239000013060 biological fluid Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0036—Porphyrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0052—Small organic molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0834—Compounds having one or more O-Si linkage
- C07F7/0838—Compounds with one or more Si-O-Si sequences
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/18—Togaviridae; Flaviviridae
- G01N2333/19—Rubella virus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85617692A | 1992-03-23 | 1992-03-23 | |
US07/856,176 | 1992-03-23 | ||
PCT/US1993/002470 WO1993019366A1 (fr) | 1992-03-23 | 1993-03-23 | Immuno-essais par fluorescence au moyen de matrices fluorescentes exemptes d'agregat et de liant de serum |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2132708A1 true CA2132708A1 (fr) | 1993-09-30 |
CA2132708C CA2132708C (fr) | 2005-05-10 |
Family
ID=25323005
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002132708A Expired - Fee Related CA2132708C (fr) | 1992-03-23 | 1993-03-23 | Immunoessais de fluorescence, utilisant des colorants fluorescents sans agregation ni liaison serique |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0632893A4 (fr) |
CA (1) | CA2132708C (fr) |
WO (1) | WO1993019366A1 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5880287A (en) * | 1990-05-15 | 1999-03-09 | Hyperion, Inc. | Polyoxyhydrocarbyl related products and methods for fluorescence assays |
US6060598A (en) * | 1990-05-15 | 2000-05-09 | Hyperion, Inc. | Fluorescence immunoassays using fluorescent dyes free of aggregation and serum binding |
US5919922A (en) * | 1990-05-15 | 1999-07-06 | Hyperion, Inc. | Fluorescent dyes free of aggregation and serum binding |
US5824799A (en) * | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
US6238931B1 (en) | 1993-09-24 | 2001-05-29 | Biosite Diagnostics, Inc. | Fluorescence energy transfer in particles |
US7322927B2 (en) | 1993-09-24 | 2008-01-29 | Biosite, Inc. | Hybrid phthalocyanine derivatives and their uses |
US7083984B2 (en) | 1993-09-24 | 2006-08-01 | Biosite, Inc. | Hybrid phthalocyanine derivatives and their uses |
JP3388753B2 (ja) * | 1995-03-23 | 2003-03-24 | バイオサイト インコーポレイテッド | 混成フタロシアニン誘導体およびその用途 |
US5876935A (en) * | 1997-01-08 | 1999-03-02 | Dade Behring Inc. | Luminescent specific binding assay |
CA2350608A1 (fr) * | 1998-11-25 | 2000-06-02 | Hyperion, Inc. | Colorants fluorescents solubles dans l'eau sans agregation et sans liaison au serum, produits et procedes associes |
EP1780213A1 (fr) | 2005-10-27 | 2007-05-02 | 3M Innovative Properties Company | Silicium-urée-azolides, leur préparation et leur utilisation dans la préparation d'isocyanates de silicone |
US9408848B2 (en) * | 2008-08-15 | 2016-08-09 | Georgetown University | Fluorescent CDK inhibitors for treatment of cancer |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0645681B2 (ja) * | 1986-02-05 | 1994-06-15 | 美浜 久春 | 修飾ヘム |
AU636562B2 (en) * | 1986-12-15 | 1993-05-06 | British Technology Group Usa, Inc. | Monomeric phthalocyanine reagents |
WO1991018007A1 (fr) * | 1990-05-15 | 1991-11-28 | Diatron Corporation | Phtalocyanatopolyethylene-glycol et saccharides phtalocyanato utilises comme reactifs de digoxine fluorescents |
US5403928A (en) * | 1990-05-15 | 1995-04-04 | Diatron Corporation | Fluorescent marker components and fluorescent probes |
EP0502723B1 (fr) * | 1991-03-05 | 1996-10-09 | Hitachi Chemical Co., Ltd. | Tétraazaporphine soluble dans l'eau et fluorochrome pour marquer |
-
1993
- 1993-03-23 CA CA002132708A patent/CA2132708C/fr not_active Expired - Fee Related
- 1993-03-23 WO PCT/US1993/002470 patent/WO1993019366A1/fr not_active Application Discontinuation
- 1993-03-23 EP EP93908390A patent/EP0632893A4/fr not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP0632893A1 (fr) | 1995-01-11 |
CA2132708C (fr) | 2005-05-10 |
WO1993019366A1 (fr) | 1993-09-30 |
EP0632893A4 (fr) | 1997-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |