CA2132528C - Agent for use as an anti-irritant - Google Patents

Agent for use as an anti-irritant Download PDF

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Publication number
CA2132528C
CA2132528C CA002132528A CA2132528A CA2132528C CA 2132528 C CA2132528 C CA 2132528C CA 002132528 A CA002132528 A CA 002132528A CA 2132528 A CA2132528 A CA 2132528A CA 2132528 C CA2132528 C CA 2132528C
Authority
CA
Canada
Prior art keywords
compound
cosmetic composition
skin
formula
addition salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002132528A
Other languages
English (en)
French (fr)
Other versions
CA2132528A1 (en
Inventor
Gerard Frans Maria Jan Cauwenbergh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of CA2132528A1 publication Critical patent/CA2132528A1/en
Application granted granted Critical
Publication of CA2132528C publication Critical patent/CA2132528C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Dental Preparations (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002132528A 1992-03-23 1993-03-16 Agent for use as an anti-irritant Expired - Fee Related CA2132528C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP92200828 1992-03-23
EP92200828.9 1992-03-23
PCT/EP1993/000634 WO1993018744A1 (en) 1992-03-23 1993-03-16 Agent for use as an anti-irritant

Publications (2)

Publication Number Publication Date
CA2132528A1 CA2132528A1 (en) 1993-09-30
CA2132528C true CA2132528C (en) 2004-06-08

Family

ID=8210497

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002132528A Expired - Fee Related CA2132528C (en) 1992-03-23 1993-03-16 Agent for use as an anti-irritant

Country Status (17)

Country Link
US (1) US5476853A (en:Method)
EP (1) EP0632717B1 (en:Method)
JP (1) JPH07504905A (en:Method)
KR (1) KR100234627B1 (en:Method)
AT (1) ATE168004T1 (en:Method)
AU (1) AU665816B2 (en:Method)
CA (1) CA2132528C (en:Method)
CY (1) CY2133B1 (en:Method)
DE (1) DE69319589T2 (en:Method)
DK (1) DK0632717T3 (en:Method)
ES (1) ES2118255T3 (en:Method)
IL (1) IL105122A (en:Method)
MX (1) MX9301627A (en:Method)
SG (1) SG48748A1 (en:Method)
TW (1) TW248530B (en:Method)
WO (1) WO1993018744A1 (en:Method)
ZA (1) ZA932025B (en:Method)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9403451D0 (en) * 1994-02-23 1994-04-13 Ciba Geigy Ag Sunscreen compositions
US5614511A (en) * 1996-03-11 1997-03-25 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Cosmetic compositions for treating itchy skin
US5670142A (en) * 1996-07-08 1997-09-23 Donald Neudecker Treatment for itch of chicken pox
US6841539B1 (en) * 1998-05-21 2005-01-11 Isis Pharmaceuticals, Inc. Compositions and methods for topical delivery of oligonucleotides
CA2357516A1 (en) * 2000-09-28 2002-03-28 Uni-Charm Corporation Absorbent article and barrier agent for absorbent article
KR100489701B1 (ko) * 2002-10-09 2005-05-16 주식회사 태평양 고농도의 트리터페노이드를 함유하는 미소화 리포좀 및 그제조방법
WO2014078868A1 (en) * 2012-11-19 2014-05-22 The Trustees Of Columbia University In The City Of New York Methods of treatment of keratinocyte-derived lesions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
DE2436883C2 (de) * 1974-07-29 1985-08-22 Schering AG, 1000 Berlin und 4709 Bergkamen Benzimidazol-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
YU39992B (en) * 1976-04-02 1985-06-30 Janssen Pharmaceutica Nv Process for obtaining new piperazine and piperidine derivatives
US4250176A (en) * 1976-12-21 1981-02-10 Janssen Pharmaceutica N.V. Piperazine derivatives
US4377578A (en) * 1976-12-21 1983-03-22 Janssen Pharmaceutica, N.V. Piperazine derivatives
US4200641A (en) * 1976-12-21 1980-04-29 Janssen Pharmaceutica, N.V. 1-[(Heterocyclyl)-alkyl]-4-diarylmethoxy piperidine derivatives
ZA914764B (en) * 1990-06-22 1992-03-25 Schering Corp Bis-benzo or benzopyrido cyclohepta piperidene,piperidylidene and piperazine compounds,compositions and methods of use
FR2665160A1 (fr) * 1990-07-26 1992-01-31 Esteve Labor Dr Nouveaux derives de 1-diphenylmethylpiperazine, leur preparation et leur application en tant que medicaments.

Also Published As

Publication number Publication date
DE69319589T2 (de) 1998-11-26
DK0632717T3 (da) 1999-02-22
EP0632717A1 (en) 1995-01-11
WO1993018744A1 (en) 1993-09-30
ZA932025B (en) 1994-09-22
TW248530B (en:Method) 1995-06-01
DE69319589D1 (de) 1998-08-13
HK1010343A1 (en) 1999-06-17
MX9301627A (es) 1994-07-29
IL105122A (en) 1998-06-15
AU3749893A (en) 1993-10-21
US5476853A (en) 1995-12-19
KR950700050A (ko) 1995-01-16
ES2118255T3 (es) 1998-09-16
CA2132528A1 (en) 1993-09-30
SG48748A1 (en) 1998-05-18
KR100234627B1 (ko) 1999-12-15
IL105122A0 (en) 1993-07-08
CY2133B1 (en) 2002-06-21
ATE168004T1 (de) 1998-07-15
JPH07504905A (ja) 1995-06-01
AU665816B2 (en) 1996-01-18
EP0632717B1 (en) 1998-07-08

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