CA2131381A1 - Nitrogen containing heterocyclic compounds useful as pharmaceuticals - Google Patents
Nitrogen containing heterocyclic compounds useful as pharmaceuticalsInfo
- Publication number
- CA2131381A1 CA2131381A1 CA002131381A CA2131381A CA2131381A1 CA 2131381 A1 CA2131381 A1 CA 2131381A1 CA 002131381 A CA002131381 A CA 002131381A CA 2131381 A CA2131381 A CA 2131381A CA 2131381 A1 CA2131381 A1 CA 2131381A1
- Authority
- CA
- Canada
- Prior art keywords
- alkyl
- compound according
- hydrogen
- formula
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9204565.7 | 1992-03-03 | ||
| GB929204565A GB9204565D0 (en) | 1992-03-03 | 1992-03-03 | Pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2131381A1 true CA2131381A1 (en) | 1993-09-16 |
Family
ID=10711400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002131381A Abandoned CA2131381A1 (en) | 1992-03-03 | 1993-02-25 | Nitrogen containing heterocyclic compounds useful as pharmaceuticals |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0629198A1 (enExample) |
| JP (1) | JPH07504428A (enExample) |
| KR (1) | KR950700285A (enExample) |
| AU (1) | AU666357B2 (enExample) |
| CA (1) | CA2131381A1 (enExample) |
| GB (1) | GB9204565D0 (enExample) |
| MX (1) | MX9301157A (enExample) |
| NZ (1) | NZ249217A (enExample) |
| TW (1) | TW279857B (enExample) |
| WO (1) | WO1993018027A1 (enExample) |
| ZA (1) | ZA931430B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5852014A (en) * | 1992-03-12 | 1998-12-22 | Smithkline Beecham P.L.C. | Condensed indole derivatives as 5HT4 -receptor antagonists |
| US5998409A (en) * | 1992-03-12 | 1999-12-07 | Smithkline Beecham Plc | Condensed indole derivatives as 5HT4 -receptor antagonists |
| WO1994008965A1 (en) * | 1992-10-16 | 1994-04-28 | Smithkline Beecham Plc | N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-ht4 receptor antagonists |
| GB9310582D0 (en) * | 1993-05-22 | 1993-07-07 | Smithkline Beecham Plc | Pharmaceuticals |
| IT1275903B1 (it) * | 1995-03-14 | 1997-10-24 | Boehringer Ingelheim Italia | Esteri e ammidi della 1,4-piperidina disostituita |
| KR20010043032A (ko) | 1998-04-28 | 2001-05-25 | 도모따께 다께시 | 1-[(1-치환-4-피페리디닐)메틸]-4-피페리딘 유도체, 그의제조방법, 그것을 함유하는의약조성물 및 이 화합물의중간체 |
| PL1664036T3 (pl) | 2003-09-03 | 2012-04-30 | Pfizer | Związki benzimidazolonu wykazujące działanie agonistyczne względem receptora 5-ht4 |
| AP2418A (en) * | 2004-06-15 | 2012-06-04 | Pfizer | Benzimidazolone carboxylic acid derivatives. |
| EA200801607A1 (ru) * | 2004-06-15 | 2008-10-30 | Пфайзер Инк. | Производные бензимидазолонкарбоновой кислоты |
| US7737163B2 (en) | 2004-06-15 | 2010-06-15 | Pfizer Inc. | Benzimidazolone carboxylic acid derivatives |
| JP2008509088A (ja) * | 2004-09-02 | 2008-03-27 | ファイザー株式会社 | ベンズイミダゾロンカルボン酸誘導体 |
| AU2006217534B8 (en) | 2005-02-22 | 2011-12-08 | Pfizer Inc. | Oxyindole derivatives as 5HT4 receptor agonists |
| EP1861377B1 (en) * | 2005-03-15 | 2010-12-29 | Pfizer, Inc. | Benzimidazolone derivatives as cb2 receptor ligands |
| NZ604423A (en) | 2010-06-24 | 2015-01-30 | Alkermes Pharma Ireland Ltd | Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3687980T2 (de) * | 1986-01-07 | 1993-06-17 | Beecham Group Plc | Indolderivate mit einer azabicyclischen seitenkette, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zusammensetzungen. |
| IT1231413B (it) * | 1987-09-23 | 1991-12-04 | Angeli Inst Spa | Derivati dell'acido benzimidazolin-2-osso-1-carbossilico utili come antagonisti dei recettori 5-ht |
-
1992
- 1992-03-03 GB GB929204565A patent/GB9204565D0/en active Pending
-
1993
- 1993-02-25 CA CA002131381A patent/CA2131381A1/en not_active Abandoned
- 1993-02-25 WO PCT/GB1993/000395 patent/WO1993018027A1/en not_active Ceased
- 1993-02-25 NZ NZ249217A patent/NZ249217A/en unknown
- 1993-02-25 JP JP5515422A patent/JPH07504428A/ja active Pending
- 1993-02-25 EP EP93904259A patent/EP0629198A1/en not_active Withdrawn
- 1993-02-25 AU AU35718/93A patent/AU666357B2/en not_active Ceased
- 1993-03-01 ZA ZA931430A patent/ZA931430B/xx unknown
- 1993-03-02 MX MX9301157A patent/MX9301157A/es unknown
- 1993-03-20 TW TW082102087A patent/TW279857B/zh active
-
1994
- 1994-09-02 KR KR1019940703105A patent/KR950700285A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU3571893A (en) | 1993-10-05 |
| AU666357B2 (en) | 1996-02-08 |
| MX9301157A (es) | 1994-07-29 |
| ZA931430B (en) | 1993-10-22 |
| EP0629198A1 (en) | 1994-12-21 |
| GB9204565D0 (en) | 1992-04-15 |
| JPH07504428A (ja) | 1995-05-18 |
| TW279857B (enExample) | 1996-07-01 |
| NZ249217A (en) | 1996-06-25 |
| KR950700285A (ko) | 1995-01-16 |
| WO1993018027A1 (en) | 1993-09-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU680453B2 (en) | Piperidine derivatives as 5-HT4 receptor antagonists | |
| AP401A (en) | Condensed indole derivatives as 5H4-receptor antagonists. | |
| NZ243993A (en) | Pharmaceutical compositions having 5-ht4 receptor antagonist activity and selected compounds having such activity | |
| CZ56094A3 (en) | The use of benzoic acid derivatives for the production of pharmaceutical preparations, benzoic acid derivatives, process of their preparation and pharmaceutical preparations in which they are comprised | |
| EP0625149A1 (en) | Benzopyran, benzothiopyran and benzofuran derivatives as 5-ht4 antagonists | |
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| AU666357B2 (en) | Indole or benzimidazole derivatives | |
| US5726187A (en) | N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-HT4 receptor antagonists | |
| JPH07291969A (ja) | ３−インドリルピペリジン | |
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| US6057340A (en) | Oxazole derivatives as serotonin-1A receptor agonists | |
| WO1999065887A1 (en) | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents | |
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| HK1012347B (en) | Condensed indole derivatives as 5-ht 4-receptor antagonists |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |