CA2129042C - Magnetically assisted binding assays using magnetically-labeled binding members - Google Patents

Magnetically assisted binding assays using magnetically-labeled binding members Download PDF

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Publication number
CA2129042C
CA2129042C CA002129042A CA2129042A CA2129042C CA 2129042 C CA2129042 C CA 2129042C CA 002129042 A CA002129042 A CA 002129042A CA 2129042 A CA2129042 A CA 2129042A CA 2129042 C CA2129042 C CA 2129042C
Authority
CA
Canada
Prior art keywords
magnetically
labeled reagent
magnetic field
analyte
binding member
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002129042A
Other languages
English (en)
French (fr)
Other versions
CA2129042A1 (en
Inventor
Thomas E. Rohr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of CA2129042A1 publication Critical patent/CA2129042A1/en
Application granted granted Critical
Publication of CA2129042C publication Critical patent/CA2129042C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CA002129042A 1992-03-20 1993-03-15 Magnetically assisted binding assays using magnetically-labeled binding members Expired - Lifetime CA2129042C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85415192A 1992-03-20 1992-03-20
US07/854,151 1992-03-20
PCT/US1993/002334 WO1993019370A1 (en) 1992-03-20 1993-03-15 Magnetically assisted binding assays using magnetically-labeled binding members

Publications (2)

Publication Number Publication Date
CA2129042A1 CA2129042A1 (en) 1993-09-30
CA2129042C true CA2129042C (en) 2002-02-19

Family

ID=25317865

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002129042A Expired - Lifetime CA2129042C (en) 1992-03-20 1993-03-15 Magnetically assisted binding assays using magnetically-labeled binding members

Country Status (8)

Country Link
EP (1) EP0631669B1 (de)
JP (1) JP2625577B2 (de)
AU (1) AU3919393A (de)
CA (1) CA2129042C (de)
DE (1) DE69333569T2 (de)
ES (1) ES2227518T3 (de)
TW (1) TW247348B (de)
WO (1) WO1993019370A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69332267D1 (de) * 1992-03-20 2002-10-10 Abbott Lab Bestimmung von bindungsaffinität mittels magnetisch markierter bindungspartner
US5998224A (en) * 1997-05-16 1999-12-07 Abbott Laboratories Magnetically assisted binding assays utilizing a magnetically responsive reagent
EP1198712A2 (de) * 1999-02-17 2002-04-24 Kilian Hennes Verfahren zum darstellen von biologisch aktivierten induktivitätsändernden partikeln sowie vorrichtung dafür
US6294342B1 (en) 1999-09-29 2001-09-25 Abbott Laboratories Magnetically assisted binding assays utilizing a magnetically responsive reagent
US6468809B1 (en) * 2000-02-04 2002-10-22 The United States Of America As Represented By The Secretary Of The Navy High efficiency magnetic sensor for magnetic particles
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US10022078B2 (en) 2004-07-13 2018-07-17 Dexcom, Inc. Analyte sensor
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7432105B2 (en) * 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7781172B2 (en) 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US7247500B2 (en) 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
CN1280428C (zh) * 2003-05-19 2006-10-18 清华大学 一种基于微小颗粒的生物芯片系统及其应用
US20060205093A1 (en) * 2003-07-30 2006-09-14 Koninklijke Philips Electronics N.V. Use of magnetic particles for determining binding between bioactive molecules
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US20060020192A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
US20090181464A1 (en) * 2006-05-09 2009-07-16 Koninklijke Philips Electronics N.V. Accurate magnetic biosensor
JP5879189B2 (ja) * 2012-04-26 2016-03-08 株式会社日立製作所 交流磁場を用いた磁気的免疫検査方法及び検査装置
JP7051004B2 (ja) * 2019-05-09 2022-04-08 三菱電機株式会社 磁性摩耗粉量測定装置及び機械装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252493A (en) * 1986-09-22 1993-10-12 Nippon Telegraph And Telephone Corporation Laser magnetic immunoassay method and apparatus therefor
DE69332267D1 (de) * 1992-03-20 2002-10-10 Abbott Lab Bestimmung von bindungsaffinität mittels magnetisch markierter bindungspartner

Also Published As

Publication number Publication date
EP0631669A1 (de) 1995-01-04
EP0631669A4 (de) 1996-10-23
CA2129042A1 (en) 1993-09-30
DE69333569T2 (de) 2005-08-04
JPH07504986A (ja) 1995-06-01
EP0631669B1 (de) 2004-07-14
WO1993019370A1 (en) 1993-09-30
ES2227518T3 (es) 2005-04-01
AU3919393A (en) 1993-10-21
DE69333569D1 (de) 2004-08-19
TW247348B (de) 1995-05-11
JP2625577B2 (ja) 1997-07-02

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