CA2113808A1 - Medical container - Google Patents
Medical containerInfo
- Publication number
- CA2113808A1 CA2113808A1 CA 2113808 CA2113808A CA2113808A1 CA 2113808 A1 CA2113808 A1 CA 2113808A1 CA 2113808 CA2113808 CA 2113808 CA 2113808 A CA2113808 A CA 2113808A CA 2113808 A1 CA2113808 A1 CA 2113808A1
- Authority
- CA
- Canada
- Prior art keywords
- drug vial
- casing
- fixing jig
- medical container
- sealed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2013—Piercing means having two piercing ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2065—Connecting means having aligning and guiding means
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
A B S T R A C T
A sealed aqueous medium container 1 is coupled, through a coupling portion 4, with a casing 3 having a cylindrical shape with a bottom portion and a through-hole 8 for air vent. A cylindrical drug vial fixing jig 13 on which a drug vial 2 is mounted so as to orient a mouth of the drug vial 2 downwardly is movably mounted in the casing 3 such that a sealed space is defined between the drug vial fixing jig 13 and the bottom portion of the casing 3. In a state where a sealed system is maintained, the drug vial 2 and the aqueous medium container 1 can be rapidly communicated with each other by a double ended needle 16, while operation for dissolving drug can be rapidly performed under sterile-condition at the time of medical care of instillation. Furthermore, a storage space is reduced and the number of components is small with a shortened overall length.
A sealed aqueous medium container 1 is coupled, through a coupling portion 4, with a casing 3 having a cylindrical shape with a bottom portion and a through-hole 8 for air vent. A cylindrical drug vial fixing jig 13 on which a drug vial 2 is mounted so as to orient a mouth of the drug vial 2 downwardly is movably mounted in the casing 3 such that a sealed space is defined between the drug vial fixing jig 13 and the bottom portion of the casing 3. In a state where a sealed system is maintained, the drug vial 2 and the aqueous medium container 1 can be rapidly communicated with each other by a double ended needle 16, while operation for dissolving drug can be rapidly performed under sterile-condition at the time of medical care of instillation. Furthermore, a storage space is reduced and the number of components is small with a shortened overall length.
Description
38~
FIELD OF ~HE INVEN~ION
The present invention relates to a medical container which is used for dissolving in the container of sealed system solid drug, such as powder drug or lyophilized drug, in aqueous medium, such as physiological saline or glucose aqueous solution, into injections at the time of use and administering the injections through instillation.
BAC~GRO~ND OF TNE_INYENTION
From a standpoint of stability of pharmaceutical preparation, some of antibiotics or blood derivatives are used for medical care as solid preparation which is dissolved immediately prior to its use so as to be intravenously administered as injections. In this case, conventionally, ~issolving operation of the solid drug is performed by communicating a drug vial with an aqueous medium container, each of which is sealed by a rubber closure, by using, for example, a hollow doublQ ended needle having pointed blades at opposite ends. If this communicating operation is per~ormed under the condition that the rubber closures of ~he !
both conkainers and the double ended needle are exposed to the air, the drug may be contaminated.
Therefore, various medical containers are proposed which enable communication between a drug vial and an aqueous medium container in a sealed system. For example, in a JP,A
61-501129(PCT W085/03432), a medical container is disclosed ~ 1 3~8 in which a capsule accommodating a drug vial and flexible container for aqueous medium are coupled by a conduit means having communicating means. Furthermore, in a JP,A 2-1277, a medical container is disclosed which enables to perform the communicating operation easily and reliably by improving a communicating mechanism.
The medical container disclosed in JP,A 61-501129 has a problem that the communicating operation ~is time consuming.
The medical container disclosed in JP,A 2-1277, shows considerable improvements in simplification of communi~
cating operation hut does not possess easiness and convenience responsive to urgent medical care requiring rapid drug a,dministration due to the need for performing the communicat-ing operation by turning a cap. Furthermore, since the overall length of this medical container is long, and the number of parts constituting this medical container is large, it is difficult to say that this medical container is suited to medical care ~or which a storage place for the drug i5 narrow and, which needs much cost for discarding used medical instruments~
On the oth~r hand, if the medical container is too long, pressure head between the medical container and a portion for administering the injections through instillation becomes small, so that pressure for injecting the injections ~ ~.3~
into a vein becomes low and, in an extreme case, it may become unable to instill the injections due to an inverse flow of blood ~rom a syringe needle held in a vein. Accordingly, in order to smoothly perform instillation based on gravity-drop, it is necessary to minimize overall length of the medical container.
The present invention has, with a view to eliminat-ing such conventional drawbacks, for its objects to provide a medical container by which a communication between a drug vial and an aqueous medium can be performed promptly under a state in which a sealed system is maintained and can be performed a dissolving operation quickly at the time of medical care of instillation under sterile-condition and, wpich makes it possible to make reduce a storage space and the number of parts and, to shorten the overall length of the medical container.
DI~C~OSURE OF THE INVEN~ION
In order to achieve the aforementioned objects, the present invention is constituted, which comprises a sealed , aqueous medium container which has a coupling mouth sealed by a thin film, a cylindrical casing which has a bottom and is sealed by a closure of elastic material and has in the bottom a coupling tube coupled with the coupling mouth by b~ing ~itted in the coupling mouth and has a body portion formed with a through~hole for exhaust, a fixing jig which has a ~ 13~8 flange formed with at least one hole for air vent and a recess in its bottom provided with an opening and the fixing jig being retained so as to be displaced in an axial direction in the casing, a drug vial which is retained in the casing so as to be displaced together with the fixing jig in a state that the coupling mouth sealed by a thin film of elastic material is ~itted into the recess, a hollow double ended needle which not only is held in a sealed space defined between the mouth of the drug vial and the bottom so as to be displaced in the axial direction but is formed so as to pierce through the closure of the casing, the closure o~ the drug vial and the thin film and has a hub for keeping piercing depth of the needle constant, a f.irst shielding member which, before the ~rug vial is depressed into the casing, closes the through~
hole so as to maintain hermetic state of the sealed space and, after the drug vial has been depressed into the casing, is disengaged ~rom the through-hole and, a second shielding member which, before the drug vial is depressed into the casing, maintains together with the first shielding member hermetic state of the sealed space and, aft~r the double ended nePdle has pierced through the closure of the casing, the closure o~ the drug vial and the thin ~ilm up to predetermined depth.
According to the present invention, since there are provided the aqueous medium container, the cylindrical casing -2~3~8 having a bottom, the drug vial fixing cylindrical jig in which tha drug vial directing the mouth downward is mounted, the hollow double ended needle having a hub at middle portion, the through-hole formed at the casing, the shielding members located at the through-hole disengageably from it, it becomes possible to communicate the drug vial with the aqueous medium container promptly under sterile-condition by simple operation and, it hecomes possibla to perform the operation for dissolving the drug into the aqueous medium guickly.
Further~ according to the present invention, since the drug vial is retained in a state that the drug vial is depressed into the casing when the dissolved drug is.in stilled, the overall length of the medical container is short a,nd, the pressure head between the medical container and a portion for instillation and administration can be made adequately large.
Furthermore, in the medical container of the present invention, the number of its parts is small and the medical container is small in size, thereby resulting in reduction of amount of wastes after use Espacially, in third and fourth embodiments o~ the present invention, the parts can be saparately discarded easily.
~RI~F DE8CRIP?ION_OF TH~ DRAWING~
FIELD OF ~HE INVEN~ION
The present invention relates to a medical container which is used for dissolving in the container of sealed system solid drug, such as powder drug or lyophilized drug, in aqueous medium, such as physiological saline or glucose aqueous solution, into injections at the time of use and administering the injections through instillation.
BAC~GRO~ND OF TNE_INYENTION
From a standpoint of stability of pharmaceutical preparation, some of antibiotics or blood derivatives are used for medical care as solid preparation which is dissolved immediately prior to its use so as to be intravenously administered as injections. In this case, conventionally, ~issolving operation of the solid drug is performed by communicating a drug vial with an aqueous medium container, each of which is sealed by a rubber closure, by using, for example, a hollow doublQ ended needle having pointed blades at opposite ends. If this communicating operation is per~ormed under the condition that the rubber closures of ~he !
both conkainers and the double ended needle are exposed to the air, the drug may be contaminated.
Therefore, various medical containers are proposed which enable communication between a drug vial and an aqueous medium container in a sealed system. For example, in a JP,A
61-501129(PCT W085/03432), a medical container is disclosed ~ 1 3~8 in which a capsule accommodating a drug vial and flexible container for aqueous medium are coupled by a conduit means having communicating means. Furthermore, in a JP,A 2-1277, a medical container is disclosed which enables to perform the communicating operation easily and reliably by improving a communicating mechanism.
The medical container disclosed in JP,A 61-501129 has a problem that the communicating operation ~is time consuming.
The medical container disclosed in JP,A 2-1277, shows considerable improvements in simplification of communi~
cating operation hut does not possess easiness and convenience responsive to urgent medical care requiring rapid drug a,dministration due to the need for performing the communicat-ing operation by turning a cap. Furthermore, since the overall length of this medical container is long, and the number of parts constituting this medical container is large, it is difficult to say that this medical container is suited to medical care ~or which a storage place for the drug i5 narrow and, which needs much cost for discarding used medical instruments~
On the oth~r hand, if the medical container is too long, pressure head between the medical container and a portion for administering the injections through instillation becomes small, so that pressure for injecting the injections ~ ~.3~
into a vein becomes low and, in an extreme case, it may become unable to instill the injections due to an inverse flow of blood ~rom a syringe needle held in a vein. Accordingly, in order to smoothly perform instillation based on gravity-drop, it is necessary to minimize overall length of the medical container.
The present invention has, with a view to eliminat-ing such conventional drawbacks, for its objects to provide a medical container by which a communication between a drug vial and an aqueous medium can be performed promptly under a state in which a sealed system is maintained and can be performed a dissolving operation quickly at the time of medical care of instillation under sterile-condition and, wpich makes it possible to make reduce a storage space and the number of parts and, to shorten the overall length of the medical container.
DI~C~OSURE OF THE INVEN~ION
In order to achieve the aforementioned objects, the present invention is constituted, which comprises a sealed , aqueous medium container which has a coupling mouth sealed by a thin film, a cylindrical casing which has a bottom and is sealed by a closure of elastic material and has in the bottom a coupling tube coupled with the coupling mouth by b~ing ~itted in the coupling mouth and has a body portion formed with a through~hole for exhaust, a fixing jig which has a ~ 13~8 flange formed with at least one hole for air vent and a recess in its bottom provided with an opening and the fixing jig being retained so as to be displaced in an axial direction in the casing, a drug vial which is retained in the casing so as to be displaced together with the fixing jig in a state that the coupling mouth sealed by a thin film of elastic material is ~itted into the recess, a hollow double ended needle which not only is held in a sealed space defined between the mouth of the drug vial and the bottom so as to be displaced in the axial direction but is formed so as to pierce through the closure of the casing, the closure o~ the drug vial and the thin film and has a hub for keeping piercing depth of the needle constant, a f.irst shielding member which, before the ~rug vial is depressed into the casing, closes the through~
hole so as to maintain hermetic state of the sealed space and, after the drug vial has been depressed into the casing, is disengaged ~rom the through-hole and, a second shielding member which, before the drug vial is depressed into the casing, maintains together with the first shielding member hermetic state of the sealed space and, aft~r the double ended nePdle has pierced through the closure of the casing, the closure o~ the drug vial and the thin ~ilm up to predetermined depth.
According to the present invention, since there are provided the aqueous medium container, the cylindrical casing -2~3~8 having a bottom, the drug vial fixing cylindrical jig in which tha drug vial directing the mouth downward is mounted, the hollow double ended needle having a hub at middle portion, the through-hole formed at the casing, the shielding members located at the through-hole disengageably from it, it becomes possible to communicate the drug vial with the aqueous medium container promptly under sterile-condition by simple operation and, it hecomes possibla to perform the operation for dissolving the drug into the aqueous medium guickly.
Further~ according to the present invention, since the drug vial is retained in a state that the drug vial is depressed into the casing when the dissolved drug is.in stilled, the overall length of the medical container is short a,nd, the pressure head between the medical container and a portion for instillation and administration can be made adequately large.
Furthermore, in the medical container of the present invention, the number of its parts is small and the medical container is small in size, thereby resulting in reduction of amount of wastes after use Espacially, in third and fourth embodiments o~ the present invention, the parts can be saparately discarded easily.
~RI~F DE8CRIP?ION_OF TH~ DRAWING~
3~8 Fig. 1 i~ a perspective view showing a medical container according to first embodiment of the present invention;
FigO 2 is an exploded perspective view of the medical container of Fig. l;
Fig. 3 is a longitudinal sectional view o~ a drug vial fixing jig in the medical container of Fig. 1;
Fig. 4 is a longitudinal sectional view of a double ended needle in the medical container of Fig. l;
Fig. 5 is a longitudinal sectional view of a casing in the medical container of Fig. l;
Fig. 6 is a partial sectional front view showing a state of the medical container of Fig. 1 prior to its c,ommunicating operation;
Fig. 7 is a partial sectional view showing a state o~ the medical container of Fig. 1 just after the communi-cating operation was started;
Fig. B is a partial sectional view showing a ~tate of the medical container of Fig. 1 when the communicating . .
operation has been finished;
Fig.9 is a sectional view of the medical container accordlng to a second embodiment of the present invention;
Fig. 10 is a perspective view of the medical container accordiny to a fourth embodiment of the presant invention;
~3~8 Fig. 11 is a partial sectional view of the medical container of Fig. 10;
Fig. 12 is a perspective view of the medical container according to a fifth embodiment of the present invention; and Fig. 13 is the medical container ac~ording to a third embodiment of the present inventionO
DE:TAI~ED DE~;CRIP~ION OF 15M13ODIMENT8 Hereinafter, an embodiment of the present invention is described referring to attached drawings.
Figs. 1 to 8 show a medical container according to a first embodiment of the present invention, in which reference numeral 1 shows an aqueous medium container, 2 shows a drug vial, 3 shows a cylindrical casing having a bottom portion and, 4 shows a coupling portion.
The aqueous medium container 1 is a flexible container made of material, such as thermoplastic polyolefin resin, flexible vinyl chloride resin, ethylene-vinyl acetate copolymer or the like and is provided, at its upper portion, with a coupling mouth 5 sealed by a thin film 32 (See Fig. 6) and is provided, at its lower portion, with medicinal solution outlet 9 sealed by a rubber closure and is ~illed with aqueous medium.
The drug vial 2 is a container, in which drug is contained and, a mouth of which is sealed by a rubber closure.
2 ~ 8 A bottom portion of the casing 3 includes a hollow coupling tube 6 formed integrally with the casing 3. Further-more, the casing 3 includes a flange portion at its upper end portion and, a suspender 7 and a suspender supporting portion 10 at upper portion of its outer wall and, through-holes 8 at four positions in nearly central portion of the outer wall.
The suspender 7 is supported by the suspender supporting portion 10 provided at the outer wall of the casing 3.
The coupling portion 4 comprises the above-mentioned coupling tube 6 and the coupling mouth 5, both o~ which are hermetically fitted and engaged.
Hereinafter, a structure of the medical container according to the above-mentioned embodiment is described in d,etail with reference to Figs 2 to 6. As shown in Fig. 2, the drug vial 2 is dîsposed such that its mouth 11 is directed downwardly. The mouth 11 is fitted into a recess 14 of a drug vial fixing jig 13. An annular packing 23 is mounted around an annular groove 12 ~ormed on a body portion of the drug vial 2. An annular pacXing 24 is mounted around an annular groove 15 for~ed on a flange portion of the drug vial fixing jig 13.
As described above, the drug vial 2 and the drug vial fixing jig 13 are hermeti~ally mounted in the casing 3 via the annular packings 23 and ~4 so as to be displaced. Between the drug vial fixin~ jig 13 and the bottom portion of the casing 6~ 3~
g 3, a sealed space is formed, in which a double ended needle 16 is located.
As shown in Fig. 3, a bottom portion of the recess 14 of the drug vial fixing jig 13 has an opening 26 for passing a blade face of the double ended needle 16 there-through. Moreover, a flange portion of the drug vial fixing jig 13 is formed with at least one hole 25 for air vent extending vertically therethroughO Hard plastic, rubber and the like are preferable as material of the drug vial fixing jig 13. The annular packing 24 can be formed integrally with the drug vial fixing jig 13. Soft plastic such as polyethyl-ene and the like, silicone rubber, butadiene rubber, isoprene rubber and the like are preferable as material of the annular p,acking 24.
As shown in Fig. 4l the double ended needle 16 has a hub 27 ~or keeping the piercing depth constant when the double ended needle 16 pierces through the rubber closure 30 of ths mouth o~ the drug vial ~See Fig. 6), an engagement portion 17 at the middle portion ~or retaining the double ended needle 16 by engaging with an annular groove 20 formed on an inner wall of the casing 3 and, liquid-tight portion 18.
Metal needle of stainless steel, hard plastic resin and the like are preferable as material of the douhle ended needle 16.
As shown in Fig. 5, in the casing 3, three annular grooves 19, 20 and 21 are formed on the inner wall. At the 3~8 part of the annular groove 20, through holeis 8 are formed.
~he coupling tube 6 located at the bottom portion of the casing 3 has a through-hole 29 in which a coupling rubber closure 22 is ~itted (See Fig. 2) and, an engagement groove 28 in which a projection 31 for engaging with the coupling portion o~ the aquPous medium container 1 is fitted (See Fig.
6). :.
As shown in Fig. 6, the drug vial 2 and the drug vial ~ixing jig 13 are mounted in the casing 3 in a state that the annular packing 23 is brought into close contact with the annular groove 19 and the annular packing 24 is brought into close contact with the annular groove 20. :
As mentioned above, a sealed space is formed between t,he drug vial fixing jig 13 and the bottom portion of the ca~ing 3 by mounting the drug vial fixing jig 13 in the casing 3. Incursion o~ air into the sealed space from out~ide is avoided and, sterility in the sealed space is guaranteed by the annular packing 23. Since the two annular packings 23, 24 are fitted into the annular grooves 19, 20, respectively, fluctuations of position of the drug vial fixing jig 13 in the casing 3 due to vibration, etc. produced during transport are avoided. On the through-hole 8, the annular packing 24 is located, which is disengaged from the through-hole 8 by depressing the bottom portion of the drug vial 2.
~3~
Hereinafter, referring to Figs. 7 and 8, method of use of the above-described medical container is described.
Fig. 7 shows a state just after an operation for communicating the drug vial 2 with the aqueous medium container i was started and, Fig. 8 shows a state after the operation has been finished. At first, the bottom portion of the drug vial 2 is pushed downwardly so as to communicate the drug vial 2 with the aqueous medium container 1. More concretely, the drug vial fixing jig 13 is descended toward the aqueous medium container 1 by depressing the bottom face o~ the drug vial 2 with a finger. By this operation, two annular packings 23, 24 are disengaged from the annular grooves 19, 20. Concurrently with disengagement of the a~nular packing 24 from the annular gro ~e 20, the through-hole 8 closed by the annular packing 2~/is opened.
Furthermore, air in the sealied space in the casing3, which space is reduced upon descent¦of the drug vial fixing ~ig 13, is discharged to outside of the casing 3 from the through-hole 8 through the holes 25 for air vent. By this discharge of the air, the drug vial fixing jig 13 retaining the drug vial 2 can descend easily without baing push~d back by the air in the reduced sealed space. Still more, the drug vial ~ixing jig 13 is depressed, end portions of the engaga-ment portion 17 of the double ended needle 16 is disengaged ~rom the annular groove 21 and, the double ended needle 16 S~ ~3~8 descends toward the aqueous medium cont~iner 1. Thus, as shown in Fig. 8, thP coupling rubber closure 22 of the coupling portion 40 and the thin film 32 and the rubber closure 30 of the mouth 11 of the drug vial 2 in ~pposite side are pierced through instantaneously. At this time, the annular packing 23 is fitted into the annular groove 20, so that the through-hole 8 is closed again. Moreover, the annular packings 23 and 24 are, respectively, fitted into the - annular grooves 20 and 21 so as to prevent ascent of the drug vial fixing jig 13.
After the drug vial 2 and the aqueous medium container 1 are communicated, they are laid horiæontally or laid in a state that the aqueous medium container 1 is raised higher than the drug vial 2 and, the aqueous medium is transferred into the drug vial 2 by depressing a surface of the aqueous medium container 1, so that the drug is dissolved.
After the drug is dîssolved completely, a solution is returned to the aqueous medium container 1, thereafter the suspender 7 is suspended to a hook o~ a stand for ~luid therapy and, a fluid therapy unit is attached to the out~et 9 o~ the aqueous medium container 1 and, the solutio~ is intravenously administered through instillation to a patient.
Fig. 9 shows a medical container according to a second embodiment of the present invention. As shown, in this embodiment, an outar wall of the drug vial fixing 3ig 13 6~3~8 extends to a body portion of the drug vial 2. Furthermore, the medical container of this embodiment is difLerent from that of Figs 1 to 8 in that, in this embodiment, the body portion of the drug vial 2 is not provided with the annular groove 12 and the annular packing 23. In this embodiment, the drug vial 2 is hermetically mounted in the drug vial fixing jig 13 such that the mouth portion of the drug vial 2 is directed downwardly. An annular packing 33 is mounted around an annular groove which is formed on an outer wall of the drug vial fixing jig 13.
By the above-described constitutions, it becomes unnecessary to ~orm an annular groove 12 on the body portion of the drug vial 2 and, glass vial usually used is utilized a.s a drug vial Constitutions other than the above-described constitutions are substantially the same as those of the embodiment o~ Figs. 1 to 8.
Fig. 13 shows a medical container according to third embodiment of the present invention, whlch is substantially the same as that shown in Figs. 1 to 8 ~xcept for that th~
engagement portion 17 of the double ende~ needle 16 acts, in place of the annular packing 24, as a shielding member ~or shielding the through-hole 8.
Figs. 10 and 11 show a medical container according to a fourth embodiment o~ the present invention.
~3~
As shown in Fig. 11, an outer wall of the drug vial fixing jig 13 of this embodiment extends to a bottom portion o~ the drug vial 2. The drug vial fixing jig ~3 has a flange portion at the lower portion and, a flange portion 34 comprising an outward flange portion 37 and an inward flange portion 38 at the upper end portion (See Fig. 10). Further, in the drug vial fixing jig 13 of this embodiment, projections 35 on the side wall of the body portion and at least two cut portions 36 are provided. Furthermore~ in the drug vial fixing jig 13 of this embodiment, on the inner wall thereof, an annular packing 39, which i~ brought into close contact with the drug vial 2, is provided.
In the medical container of this embodiment, ascent o~ the drug vial 2, which occurs when the rubber closure 30 of the mouth portion of the drug vial 2, thin film 32 and, the rubber closure 22 of tha coupling portion are pierced through by the double ended needle 16, is prevented by the inward flange portion 38 provided on the drug vial drug vial fixing jig 13 and, by the projections 35 each ~f whirh has a wedgy form at lower portion thereof~ When the drug vial ~ixing jig 13 descends by communicating operation which is performed by depressing the bottom portion oE theJ drug ~ial 2, the projection 35 is brought into contact with the inner wall of the casing 3 resulting in a side wall of upper portion of the drug vial fixing jig 13 being deformed inwardly toward a 5 .
6~
center of an axis and, the bottom portion of the drug vial 2 is depressed by the inward flange portion 38 with the deforma-tion of the side wall, whereby the ascent of the drug vial 2 is prevented.
Moreover, the medical container of this embodiment has a feature that discarding separately after use is performed easily. After the medical container of the this embodiment has been used, the outward flange portion 37 provided at the upper end portion of the drug vial fixing jig 13 is pulled upwardly, whereby the drug vial fixing jig 13 can be taken out from the casing. After the drug vial fixing jig 13 has been taken outwardly, the drug vial 2 mounted in the drug vial fixing jig 13 can be taken outwardly by holding and p,ulling upwardly with fingers a ~ide wall of the drug vial 2 exposed by the cut portions 36.
I'he annular packing 39 provided at the inner wall of the body portion of the drug vial fixing jig 13 prevents hermetic state in the casing 3 from being spoiled by disperslon of diameter size of the body\portion of the drug vial 2 which occurs due to mass production. Meanwhile, although three annular packings 24, 33 and 39 on the drug vial fixing jig 13 may be mounted around the annular grooves which are made around the drug vial fixing ~ig 13, they may be made integrally with the drug vial fixing jig 13 ~1~38~8 Fig. 12 shows a medical container according to fifth embodiment of the present invention.
As shown, the through-hole 8 is formed in the annular groove 21 with which the double ended needle 16 is engaged, thereby an engagement portion 17 of the double ended needle 16 becomes a shielding member closing and opening the through-hole 8.
The other constitutions are substantially identical with those of the medical contain~r of Figs. 10 and 11.
I
!
~.,
FigO 2 is an exploded perspective view of the medical container of Fig. l;
Fig. 3 is a longitudinal sectional view o~ a drug vial fixing jig in the medical container of Fig. 1;
Fig. 4 is a longitudinal sectional view of a double ended needle in the medical container of Fig. l;
Fig. 5 is a longitudinal sectional view of a casing in the medical container of Fig. l;
Fig. 6 is a partial sectional front view showing a state of the medical container of Fig. 1 prior to its c,ommunicating operation;
Fig. 7 is a partial sectional view showing a state o~ the medical container of Fig. 1 just after the communi-cating operation was started;
Fig. B is a partial sectional view showing a ~tate of the medical container of Fig. 1 when the communicating . .
operation has been finished;
Fig.9 is a sectional view of the medical container accordlng to a second embodiment of the present invention;
Fig. 10 is a perspective view of the medical container accordiny to a fourth embodiment of the presant invention;
~3~8 Fig. 11 is a partial sectional view of the medical container of Fig. 10;
Fig. 12 is a perspective view of the medical container according to a fifth embodiment of the present invention; and Fig. 13 is the medical container ac~ording to a third embodiment of the present inventionO
DE:TAI~ED DE~;CRIP~ION OF 15M13ODIMENT8 Hereinafter, an embodiment of the present invention is described referring to attached drawings.
Figs. 1 to 8 show a medical container according to a first embodiment of the present invention, in which reference numeral 1 shows an aqueous medium container, 2 shows a drug vial, 3 shows a cylindrical casing having a bottom portion and, 4 shows a coupling portion.
The aqueous medium container 1 is a flexible container made of material, such as thermoplastic polyolefin resin, flexible vinyl chloride resin, ethylene-vinyl acetate copolymer or the like and is provided, at its upper portion, with a coupling mouth 5 sealed by a thin film 32 (See Fig. 6) and is provided, at its lower portion, with medicinal solution outlet 9 sealed by a rubber closure and is ~illed with aqueous medium.
The drug vial 2 is a container, in which drug is contained and, a mouth of which is sealed by a rubber closure.
2 ~ 8 A bottom portion of the casing 3 includes a hollow coupling tube 6 formed integrally with the casing 3. Further-more, the casing 3 includes a flange portion at its upper end portion and, a suspender 7 and a suspender supporting portion 10 at upper portion of its outer wall and, through-holes 8 at four positions in nearly central portion of the outer wall.
The suspender 7 is supported by the suspender supporting portion 10 provided at the outer wall of the casing 3.
The coupling portion 4 comprises the above-mentioned coupling tube 6 and the coupling mouth 5, both o~ which are hermetically fitted and engaged.
Hereinafter, a structure of the medical container according to the above-mentioned embodiment is described in d,etail with reference to Figs 2 to 6. As shown in Fig. 2, the drug vial 2 is dîsposed such that its mouth 11 is directed downwardly. The mouth 11 is fitted into a recess 14 of a drug vial fixing jig 13. An annular packing 23 is mounted around an annular groove 12 ~ormed on a body portion of the drug vial 2. An annular pacXing 24 is mounted around an annular groove 15 for~ed on a flange portion of the drug vial fixing jig 13.
As described above, the drug vial 2 and the drug vial fixing jig 13 are hermeti~ally mounted in the casing 3 via the annular packings 23 and ~4 so as to be displaced. Between the drug vial fixin~ jig 13 and the bottom portion of the casing 6~ 3~
g 3, a sealed space is formed, in which a double ended needle 16 is located.
As shown in Fig. 3, a bottom portion of the recess 14 of the drug vial fixing jig 13 has an opening 26 for passing a blade face of the double ended needle 16 there-through. Moreover, a flange portion of the drug vial fixing jig 13 is formed with at least one hole 25 for air vent extending vertically therethroughO Hard plastic, rubber and the like are preferable as material of the drug vial fixing jig 13. The annular packing 24 can be formed integrally with the drug vial fixing jig 13. Soft plastic such as polyethyl-ene and the like, silicone rubber, butadiene rubber, isoprene rubber and the like are preferable as material of the annular p,acking 24.
As shown in Fig. 4l the double ended needle 16 has a hub 27 ~or keeping the piercing depth constant when the double ended needle 16 pierces through the rubber closure 30 of ths mouth o~ the drug vial ~See Fig. 6), an engagement portion 17 at the middle portion ~or retaining the double ended needle 16 by engaging with an annular groove 20 formed on an inner wall of the casing 3 and, liquid-tight portion 18.
Metal needle of stainless steel, hard plastic resin and the like are preferable as material of the douhle ended needle 16.
As shown in Fig. 5, in the casing 3, three annular grooves 19, 20 and 21 are formed on the inner wall. At the 3~8 part of the annular groove 20, through holeis 8 are formed.
~he coupling tube 6 located at the bottom portion of the casing 3 has a through-hole 29 in which a coupling rubber closure 22 is ~itted (See Fig. 2) and, an engagement groove 28 in which a projection 31 for engaging with the coupling portion o~ the aquPous medium container 1 is fitted (See Fig.
6). :.
As shown in Fig. 6, the drug vial 2 and the drug vial ~ixing jig 13 are mounted in the casing 3 in a state that the annular packing 23 is brought into close contact with the annular groove 19 and the annular packing 24 is brought into close contact with the annular groove 20. :
As mentioned above, a sealed space is formed between t,he drug vial fixing jig 13 and the bottom portion of the ca~ing 3 by mounting the drug vial fixing jig 13 in the casing 3. Incursion o~ air into the sealed space from out~ide is avoided and, sterility in the sealed space is guaranteed by the annular packing 23. Since the two annular packings 23, 24 are fitted into the annular grooves 19, 20, respectively, fluctuations of position of the drug vial fixing jig 13 in the casing 3 due to vibration, etc. produced during transport are avoided. On the through-hole 8, the annular packing 24 is located, which is disengaged from the through-hole 8 by depressing the bottom portion of the drug vial 2.
~3~
Hereinafter, referring to Figs. 7 and 8, method of use of the above-described medical container is described.
Fig. 7 shows a state just after an operation for communicating the drug vial 2 with the aqueous medium container i was started and, Fig. 8 shows a state after the operation has been finished. At first, the bottom portion of the drug vial 2 is pushed downwardly so as to communicate the drug vial 2 with the aqueous medium container 1. More concretely, the drug vial fixing jig 13 is descended toward the aqueous medium container 1 by depressing the bottom face o~ the drug vial 2 with a finger. By this operation, two annular packings 23, 24 are disengaged from the annular grooves 19, 20. Concurrently with disengagement of the a~nular packing 24 from the annular gro ~e 20, the through-hole 8 closed by the annular packing 2~/is opened.
Furthermore, air in the sealied space in the casing3, which space is reduced upon descent¦of the drug vial fixing ~ig 13, is discharged to outside of the casing 3 from the through-hole 8 through the holes 25 for air vent. By this discharge of the air, the drug vial fixing jig 13 retaining the drug vial 2 can descend easily without baing push~d back by the air in the reduced sealed space. Still more, the drug vial ~ixing jig 13 is depressed, end portions of the engaga-ment portion 17 of the double ended needle 16 is disengaged ~rom the annular groove 21 and, the double ended needle 16 S~ ~3~8 descends toward the aqueous medium cont~iner 1. Thus, as shown in Fig. 8, thP coupling rubber closure 22 of the coupling portion 40 and the thin film 32 and the rubber closure 30 of the mouth 11 of the drug vial 2 in ~pposite side are pierced through instantaneously. At this time, the annular packing 23 is fitted into the annular groove 20, so that the through-hole 8 is closed again. Moreover, the annular packings 23 and 24 are, respectively, fitted into the - annular grooves 20 and 21 so as to prevent ascent of the drug vial fixing jig 13.
After the drug vial 2 and the aqueous medium container 1 are communicated, they are laid horiæontally or laid in a state that the aqueous medium container 1 is raised higher than the drug vial 2 and, the aqueous medium is transferred into the drug vial 2 by depressing a surface of the aqueous medium container 1, so that the drug is dissolved.
After the drug is dîssolved completely, a solution is returned to the aqueous medium container 1, thereafter the suspender 7 is suspended to a hook o~ a stand for ~luid therapy and, a fluid therapy unit is attached to the out~et 9 o~ the aqueous medium container 1 and, the solutio~ is intravenously administered through instillation to a patient.
Fig. 9 shows a medical container according to a second embodiment of the present invention. As shown, in this embodiment, an outar wall of the drug vial fixing 3ig 13 6~3~8 extends to a body portion of the drug vial 2. Furthermore, the medical container of this embodiment is difLerent from that of Figs 1 to 8 in that, in this embodiment, the body portion of the drug vial 2 is not provided with the annular groove 12 and the annular packing 23. In this embodiment, the drug vial 2 is hermetically mounted in the drug vial fixing jig 13 such that the mouth portion of the drug vial 2 is directed downwardly. An annular packing 33 is mounted around an annular groove which is formed on an outer wall of the drug vial fixing jig 13.
By the above-described constitutions, it becomes unnecessary to ~orm an annular groove 12 on the body portion of the drug vial 2 and, glass vial usually used is utilized a.s a drug vial Constitutions other than the above-described constitutions are substantially the same as those of the embodiment o~ Figs. 1 to 8.
Fig. 13 shows a medical container according to third embodiment of the present invention, whlch is substantially the same as that shown in Figs. 1 to 8 ~xcept for that th~
engagement portion 17 of the double ende~ needle 16 acts, in place of the annular packing 24, as a shielding member ~or shielding the through-hole 8.
Figs. 10 and 11 show a medical container according to a fourth embodiment o~ the present invention.
~3~
As shown in Fig. 11, an outer wall of the drug vial fixing jig 13 of this embodiment extends to a bottom portion o~ the drug vial 2. The drug vial fixing jig ~3 has a flange portion at the lower portion and, a flange portion 34 comprising an outward flange portion 37 and an inward flange portion 38 at the upper end portion (See Fig. 10). Further, in the drug vial fixing jig 13 of this embodiment, projections 35 on the side wall of the body portion and at least two cut portions 36 are provided. Furthermore~ in the drug vial fixing jig 13 of this embodiment, on the inner wall thereof, an annular packing 39, which i~ brought into close contact with the drug vial 2, is provided.
In the medical container of this embodiment, ascent o~ the drug vial 2, which occurs when the rubber closure 30 of the mouth portion of the drug vial 2, thin film 32 and, the rubber closure 22 of tha coupling portion are pierced through by the double ended needle 16, is prevented by the inward flange portion 38 provided on the drug vial drug vial fixing jig 13 and, by the projections 35 each ~f whirh has a wedgy form at lower portion thereof~ When the drug vial ~ixing jig 13 descends by communicating operation which is performed by depressing the bottom portion oE theJ drug ~ial 2, the projection 35 is brought into contact with the inner wall of the casing 3 resulting in a side wall of upper portion of the drug vial fixing jig 13 being deformed inwardly toward a 5 .
6~
center of an axis and, the bottom portion of the drug vial 2 is depressed by the inward flange portion 38 with the deforma-tion of the side wall, whereby the ascent of the drug vial 2 is prevented.
Moreover, the medical container of this embodiment has a feature that discarding separately after use is performed easily. After the medical container of the this embodiment has been used, the outward flange portion 37 provided at the upper end portion of the drug vial fixing jig 13 is pulled upwardly, whereby the drug vial fixing jig 13 can be taken out from the casing. After the drug vial fixing jig 13 has been taken outwardly, the drug vial 2 mounted in the drug vial fixing jig 13 can be taken outwardly by holding and p,ulling upwardly with fingers a ~ide wall of the drug vial 2 exposed by the cut portions 36.
I'he annular packing 39 provided at the inner wall of the body portion of the drug vial fixing jig 13 prevents hermetic state in the casing 3 from being spoiled by disperslon of diameter size of the body\portion of the drug vial 2 which occurs due to mass production. Meanwhile, although three annular packings 24, 33 and 39 on the drug vial fixing jig 13 may be mounted around the annular grooves which are made around the drug vial fixing ~ig 13, they may be made integrally with the drug vial fixing jig 13 ~1~38~8 Fig. 12 shows a medical container according to fifth embodiment of the present invention.
As shown, the through-hole 8 is formed in the annular groove 21 with which the double ended needle 16 is engaged, thereby an engagement portion 17 of the double ended needle 16 becomes a shielding member closing and opening the through-hole 8.
The other constitutions are substantially identical with those of the medical contain~r of Figs. 10 and 11.
I
!
~.,
Claims (4)
1. Medical container comprising:
a sealed aqueous medium container which has a coupling mouth sealed by a thin film;
a cylindrical casing which has a bottom portion and is sealed by a closure of elastic material and has in said bottom portion a coupling tube coupled with said coupling mouth by being fitted in said coupling mouth and has a body portion formed with a through-hole for exhaust;
a fixing jig which has a flange formed with at least one hole for air vent and a recess at its bottom provided with an opening and, said fixing jig being retained so as to be displaced in an axial direction in said casing;
a drug vial which is retained in said casing so as to be displaced together with said fixing jig in a state that said coupling mouth sealed by a thin film of elastic material is fitted in said recess;
a hollow double ended needle which not only is held in a sealed space defined between said mouth of said drug vial and said bottom portion so as to be displaced in the axial direction but is formed so as to pierce through said closure of said casing, said closure of said drug vial and said thin film and has a hub for keeping piercing depth of said needle constant;
a first shielding member which, before said drug vial is depressed into said casing, closes said through-hole so as to maintain hermetic state of said sealed space and, after said drug vial has been depressed into said casing, is disengaged from said through-hole; and a second shielding member which, before said drug vial is depressed into said casing, maintains together with said first shielding member hermetic state of said sealed space and, after said double ended needle has pierced through said closure of said casing, said closure of said drug vial and said thin film up to predetermined depth.
a sealed aqueous medium container which has a coupling mouth sealed by a thin film;
a cylindrical casing which has a bottom portion and is sealed by a closure of elastic material and has in said bottom portion a coupling tube coupled with said coupling mouth by being fitted in said coupling mouth and has a body portion formed with a through-hole for exhaust;
a fixing jig which has a flange formed with at least one hole for air vent and a recess at its bottom provided with an opening and, said fixing jig being retained so as to be displaced in an axial direction in said casing;
a drug vial which is retained in said casing so as to be displaced together with said fixing jig in a state that said coupling mouth sealed by a thin film of elastic material is fitted in said recess;
a hollow double ended needle which not only is held in a sealed space defined between said mouth of said drug vial and said bottom portion so as to be displaced in the axial direction but is formed so as to pierce through said closure of said casing, said closure of said drug vial and said thin film and has a hub for keeping piercing depth of said needle constant;
a first shielding member which, before said drug vial is depressed into said casing, closes said through-hole so as to maintain hermetic state of said sealed space and, after said drug vial has been depressed into said casing, is disengaged from said through-hole; and a second shielding member which, before said drug vial is depressed into said casing, maintains together with said first shielding member hermetic state of said sealed space and, after said double ended needle has pierced through said closure of said casing, said closure of said drug vial and said thin film up to predetermined depth.
2 Medical container as claimed in Claim 1 wherein said first shield member is provided on outside portion of said fixing jig and said shielding member is provided around outside portion of said drug vial.
3 Medical container as claimed in Claim 1 wherein said first and second shielding members are provided around outside portion of said fixing jig, respectively.
4 Medical container as claimed in Claim 1 wherein said first shielding member is provided around periphery portion of said hub of said double ended needle.
Medical container as claimed in Claim 3 or 4 wherein said fixing jig is provided with an outward flange portion and an inward flange portion for retaining said drug vial and a cut portion on an end portion of said fixing jig opposite to said recess.
6 Medical container as claimed in Claim 5 wherein said fixing jig is provided with outward projections, each lower portion of which has wedgy form and engages with an end portion of said casing when said drug vial is depressed into said casing.
Medical container as claimed in Claim 3 or 4 wherein said fixing jig is provided with an outward flange portion and an inward flange portion for retaining said drug vial and a cut portion on an end portion of said fixing jig opposite to said recess.
6 Medical container as claimed in Claim 5 wherein said fixing jig is provided with outward projections, each lower portion of which has wedgy form and engages with an end portion of said casing when said drug vial is depressed into said casing.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP48268/1992 | 1992-06-16 | ||
| JP4826892 | 1992-06-16 | ||
| JP2924593U JPH0686738U (en) | 1992-06-16 | 1993-05-07 | Medical container |
| JP29245/1992 | 1993-05-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2113808A1 true CA2113808A1 (en) | 1993-12-23 |
Family
ID=26367420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2113808 Abandoned CA2113808A1 (en) | 1992-06-16 | 1993-06-11 | Medical container |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0598918A4 (en) |
| JP (1) | JPH0686738U (en) |
| CA (1) | CA2113808A1 (en) |
| FI (1) | FI940699A (en) |
| WO (1) | WO1993025175A1 (en) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5543042A (en) * | 1995-03-30 | 1996-08-06 | Abbott Laboratories | Waste agent reservoir for suction drainage system |
| DE19513666C1 (en) * | 1995-04-11 | 1996-11-28 | Behringwerke Ag | Device for bringing together a first liquid and a second solid or liquid component by means of negative pressure under sterile conditions |
| DE10005813A1 (en) * | 2000-02-10 | 2001-08-23 | Wolfgang Vilmar | Mixing unit comprises container which is housed in hollow cylinder in further, axially displaceable hollow cylinder provided at its lower end with rubber membrane |
| EP2412359A1 (en) * | 2006-09-29 | 2012-02-01 | Infa S.A. | Packaging system for pharmaceutical compositions and kit for intravenous administration |
| FR2948284B1 (en) * | 2009-07-27 | 2011-09-30 | Technoflex | INFUSION DEVICE AND CONTAINER FOR MEDICAL USE EQUIPPED WITH AT LEAST ONE SUCH DEVICE |
| JP5981341B2 (en) * | 2009-09-14 | 2016-08-31 | ネステク ソシエテ アノニム | Package with foil seal and penetration means |
| AU2012225163B2 (en) * | 2011-03-04 | 2016-05-12 | Duoject Medical Systems Inc. | Easy linking transfer system |
| CN102283775B (en) * | 2011-09-14 | 2013-11-20 | 重庆莱美药业股份有限公司 | Soft bag with dual-needle medicament feeder |
| JP6128121B2 (en) * | 2012-05-23 | 2017-05-17 | ニプロ株式会社 | Medical container |
| IL221634A0 (en) | 2012-08-26 | 2012-12-31 | Medimop Medical Projects Ltd | Universal drug vial adapter |
| IL225734A0 (en) | 2013-04-14 | 2013-09-30 | Medimop Medical Projects Ltd | Ready-to-use drug vial assemblages including drug vial and drug vial closure having fluid transfer member, and drug vial closure therefor |
| CN105228676B (en) | 2013-05-10 | 2018-01-05 | 麦迪麦珀医疗工程有限公司 | Include the medical treatment device of the vial adapter with inline dry kit |
| CN205626622U (en) | 2013-08-07 | 2016-10-12 | 麦迪麦珀医疗工程有限公司 | Liquid transfer device that is used together with infusion container |
| USD794183S1 (en) | 2014-03-19 | 2017-08-08 | Medimop Medical Projects Ltd. | Dual ended liquid transfer spike |
| CN113143759B (en) | 2015-07-16 | 2024-01-30 | 西部制药服务以色列有限公司 | Liquid drug transfer device for secure telescopic snap-fit on an injection vial |
| EP3324915A1 (en) * | 2015-07-20 | 2018-05-30 | Medimop Medical Projects Ltd. | Liquid drug transfer device with set-up vial retention flex members |
| USD801522S1 (en) | 2015-11-09 | 2017-10-31 | Medimop Medical Projects Ltd. | Fluid transfer assembly |
| JP6523569B2 (en) | 2015-11-25 | 2019-06-05 | ウエスト・ファーマ．サービシーズ・イスラエル，リミテッド | Dual vial adapter assembly comprising a vial adapter having a self sealing access valve |
| IL245803A0 (en) | 2016-05-24 | 2016-08-31 | West Pharma Services Il Ltd | Dual vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter |
| IL245800A0 (en) | 2016-05-24 | 2016-08-31 | West Pharma Services Il Ltd | Dual vial adapter assemblages including identical twin vial adapters |
| IL246073A0 (en) | 2016-06-06 | 2016-08-31 | West Pharma Services Il Ltd | Fluid transfer devices for use with drug pump cartridge having slidable driving plunger |
| IL247376A0 (en) | 2016-08-21 | 2016-12-29 | Medimop Medical Projects Ltd | Syringe assembly |
| USD832430S1 (en) | 2016-11-15 | 2018-10-30 | West Pharma. Services IL, Ltd. | Dual vial adapter assemblage |
| IL249408A0 (en) | 2016-12-06 | 2017-03-30 | Medimop Medical Projects Ltd | Liquid transfer device for use with infusion liquid container and pincers-like hand tool for use therewith for releasing intact drug vial therefrom |
| IL251458A0 (en) | 2017-03-29 | 2017-06-29 | Medimop Medical Projects Ltd | User actuated liquid drug transfer devices for use in ready-to-use (rtu) liquid drug transfer assemblages |
| IL254802A0 (en) | 2017-09-29 | 2017-12-31 | Medimop Medical Projects Ltd | Dual vial adapter assemblages with twin vented female vial adapters |
| JP1630477S (en) | 2018-07-06 | 2019-05-07 | ||
| USD923812S1 (en) | 2019-01-16 | 2021-06-29 | West Pharma. Services IL, Ltd. | Medication mixing apparatus |
| JP1648075S (en) | 2019-01-17 | 2019-12-16 | ||
| WO2020157719A1 (en) | 2019-01-31 | 2020-08-06 | West Pharma. Services Il, Ltd | Liquid transfer device |
| CA3135248C (en) | 2019-04-30 | 2024-01-02 | Yossi Bar-El | Liquid transfer device with dual lumen iv spike |
| USD956958S1 (en) | 2020-07-13 | 2022-07-05 | West Pharma. Services IL, Ltd. | Liquid transfer device |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE60235B1 (en) * | 1986-09-18 | 1994-06-15 | Kabi Pharmacia Ab | "Connector and disposable assembly utilising said connector" |
| JPH021277A (en) * | 1988-03-31 | 1990-01-05 | Fujisawa Pharmaceut Co Ltd | Infusion container |
| JPH0337067A (en) * | 1989-07-03 | 1991-02-18 | Hishiyama Seiyaku Kk | Transfusion container |
-
1993
- 1993-05-07 JP JP2924593U patent/JPH0686738U/en active Pending
- 1993-06-11 EP EP19930913513 patent/EP0598918A4/en not_active Withdrawn
- 1993-06-11 CA CA 2113808 patent/CA2113808A1/en not_active Abandoned
- 1993-06-11 WO PCT/JP1993/000789 patent/WO1993025175A1/en not_active Application Discontinuation
-
1994
- 1994-02-15 FI FI940699A patent/FI940699A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0598918A4 (en) | 1994-12-07 |
| EP0598918A1 (en) | 1994-06-01 |
| FI940699A0 (en) | 1994-02-15 |
| FI940699A (en) | 1994-02-15 |
| WO1993025175A1 (en) | 1993-12-23 |
| JPH0686738U (en) | 1994-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |