CA2111214A1 - Composition et traitement avec peptides biologiquement actifs ayant des substitutions c-terminales - Google Patents

Composition et traitement avec peptides biologiquement actifs ayant des substitutions c-terminales

Info

Publication number
CA2111214A1
CA2111214A1 CA002111214A CA2111214A CA2111214A1 CA 2111214 A1 CA2111214 A1 CA 2111214A1 CA 002111214 A CA002111214 A CA 002111214A CA 2111214 A CA2111214 A CA 2111214A CA 2111214 A1 CA2111214 A1 CA 2111214A1
Authority
CA
Canada
Prior art keywords
peptide
amino acid
ala
seq
lys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002111214A
Other languages
English (en)
Inventor
W. Lee Maloy
U. Prasad Kari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Magainin Pharmaceuticals Inc
Original Assignee
Magainin Sciences Inc
Magainin Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Magainin Sciences Inc, Magainin Pharmaceuticals Inc filed Critical Magainin Sciences Inc
Publication of CA2111214A1 publication Critical patent/CA2111214A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/463—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from amphibians
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002111214A 1991-06-12 1992-06-01 Composition et traitement avec peptides biologiquement actifs ayant des substitutions c-terminales Abandoned CA2111214A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71371691A 1991-06-12 1991-06-12
US713,716 1991-06-12

Publications (1)

Publication Number Publication Date
CA2111214A1 true CA2111214A1 (fr) 1992-12-23

Family

ID=24867235

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002111214A Abandoned CA2111214A1 (fr) 1991-06-12 1992-06-01 Composition et traitement avec peptides biologiquement actifs ayant des substitutions c-terminales

Country Status (5)

Country Link
EP (1) EP0590044A4 (fr)
JP (1) JPH06511234A (fr)
AU (1) AU2161592A (fr)
CA (1) CA2111214A1 (fr)
WO (1) WO1992022317A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2137087A1 (fr) * 1992-06-01 1993-12-09 U. Prasad Kari Peptides a action biologique substitues en position n-terminale
US6348445B1 (en) 1992-06-01 2002-02-19 Magainin Pharmaceuticals, Inc. Biologically active peptides with reduced toxicity in animals and a method for preparing same
US5593866A (en) * 1992-08-21 1997-01-14 The University Of British Columbia Cationic peptides and method for production
US5847047A (en) * 1993-06-22 1998-12-08 E. I. Du Pont De Nemours And Company Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type
FR2734492B1 (fr) * 1995-05-22 1997-06-27 Rossignol Sa Planche de glisse sur neige comportant un dispositif pour le montage d'une fixation d'une chaussure
US6057291A (en) 1995-06-02 2000-05-02 University Of British Columbia Antimicrobial cationic peptides
FR2735983B1 (fr) 1995-06-29 1997-12-05 Centre Nat Rech Scient Peptide permettant de modifier l'activite du systeme immunitaire humain ou animal
ES2316154T3 (es) 1995-08-23 2009-04-01 University Of British Columbia Peptidos cationicos antimicrobianos y procedimientos de seleccion de los mismos.
US8283315B2 (en) 1998-08-28 2012-10-09 Lytix Biopharma As Inhibition of tumour growth
GB9818938D0 (en) * 1998-08-28 1998-10-21 Alpharma As Bioactive peptides
EP1257567A2 (fr) * 2000-02-15 2002-11-20 Ohio University Peptides cationiques presentant une structure secondaire amphipatique de feuillet beta et leurs utilisations
WO2009094634A1 (fr) 2008-01-24 2009-07-30 Esperance Pharmaceuticals Produits de fusion recombinants à domaine lytique et leurs procédés de fabrication et d'utilisation
CN105121472A (zh) 2012-10-30 2015-12-02 埃斯佩兰斯医药公司 抗体/药物缀合物及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810777A (en) * 1987-03-04 1989-03-07 The United States Of America As Represented By The Department Of Health And Human Services Antimicrobial compounds
CA2007913A1 (fr) * 1989-01-30 1990-07-30 Michael Zasloff Compose et traitement avec une combinaison de peptides
ES2095255T3 (es) * 1989-07-07 1997-02-16 Scripps Research Inst Analogos de sustitucion de peptidos magainina.

Also Published As

Publication number Publication date
EP0590044A4 (en) 1996-06-12
EP0590044A1 (fr) 1994-04-06
JPH06511234A (ja) 1994-12-15
AU2161592A (en) 1993-01-12
WO1992022317A1 (fr) 1992-12-23

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Legal Events

Date Code Title Description
FZDE Dead