CA2109435A1 - Compositions d'acide n-(phosphonoacetyl)-l-aspartique et methodes pour leur utilisation comme agents antiviraux a large spectre - Google Patents
Compositions d'acide n-(phosphonoacetyl)-l-aspartique et methodes pour leur utilisation comme agents antiviraux a large spectreInfo
- Publication number
- CA2109435A1 CA2109435A1 CA2109435A CA2109435A CA2109435A1 CA 2109435 A1 CA2109435 A1 CA 2109435A1 CA 2109435 A CA2109435 A CA 2109435A CA 2109435 A CA2109435 A CA 2109435A CA 2109435 A1 CA2109435 A1 CA 2109435A1
- Authority
- CA
- Canada
- Prior art keywords
- compositions
- methods
- broad spectrum
- phosphonoacetyl
- aspartic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85345492A | 1992-03-18 | 1992-03-18 | |
US853,454 | 1992-03-18 | ||
US08/032,234 US5491135A (en) | 1992-03-18 | 1993-03-17 | Compositions of N-(phosphonoacetyl)-L-aspartic acid and methods of their use as broad spectrum antivirals |
US032,234 | 1993-03-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2109435A1 true CA2109435A1 (fr) | 1993-09-19 |
CA2109435C CA2109435C (fr) | 1997-03-11 |
Family
ID=26708159
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002109435A Expired - Fee Related CA2109435C (fr) | 1992-03-18 | 1993-03-18 | Compositions d'acide n-(phosphonoacetyl)-l-aspartique et methodes pour leur utilisation comme agents antiviraux a large spectre |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0660710A1 (fr) |
JP (1) | JPH07507770A (fr) |
CN (1) | CN1080853A (fr) |
AU (1) | AU3965993A (fr) |
BR (1) | BR9306123A (fr) |
CA (1) | CA2109435C (fr) |
IL (1) | IL105090A (fr) |
IS (1) | IS3987A (fr) |
MX (1) | MX9301527A (fr) |
WO (1) | WO1993018763A1 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6440980B1 (en) * | 1996-09-17 | 2002-08-27 | Avanir Pharmaceuticals | Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs |
US20030100532A1 (en) | 1997-02-14 | 2003-05-29 | Gary S. Jacob | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
DK1030839T3 (da) | 1997-11-10 | 2004-05-03 | Searle & Co | Anvendelse af alkylerede iminosukkere til behandling af multidrugresistens |
EA004705B1 (ru) | 1998-02-12 | 2004-06-24 | Дж.Д.Серл Энд Ко. | Применение n-замещенных 1,5-дидезокси-1,5-имино-d-глюцитных производных для лечения инфекций, вызываемых вирусами гепатита |
US6689759B1 (en) | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
US6515028B1 (en) | 1999-02-12 | 2003-02-04 | G.D. Searle & Co. | Glucamine compounds for treating hepatitis virus infections |
US6545021B1 (en) | 1999-02-12 | 2003-04-08 | G.D. Searle & Co. | Use of substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections |
AU2012101A (en) * | 1999-12-20 | 2001-07-03 | New Pharma Research Sweden Ab | Veterinary compositions |
DE10138912A1 (de) * | 2001-08-08 | 2003-02-27 | Medinnova Ges Med Innovationen | Verwendung von Wirksubstanzen zur Prophylaxe und/oder Therapie von Viruserkrankungen sowie Testsystem zum Auffinden solcher Wirksubstanzen |
DE10343365A1 (de) * | 2003-09-17 | 2005-04-14 | Biosphings Ag | Pharmazeutische Formulierungen von Xanthogenaten und Hemmstoffen der viralen Nukleinsäurereplikation |
US8236768B2 (en) | 2008-10-03 | 2012-08-07 | 3B Pharmaceuticals, Inc. | Topical antiviral formulations |
CN111317733B (zh) * | 2020-03-24 | 2022-07-12 | 中国人民解放军海军军医大学 | 利福霉素类抗生素在制备抗黄热病毒感染药物中的应用 |
WO2021189444A1 (fr) * | 2020-03-24 | 2021-09-30 | 中国人民解放军海军军医大学 | Utilisation d'antibiotiques du type rifamycine dans la préparation de médicaments contre des infections par le virus de la fièvre jaune |
CN111419839A (zh) * | 2020-03-31 | 2020-07-17 | 远见生物科技(上海)有限公司 | 利福霉素的新用途 |
WO2021221111A1 (fr) * | 2020-04-30 | 2021-11-04 | 国立大学法人京都大学 | Agent prophylactique ou thérapeutique pour des maladies liées au virus de l'arn |
EP4313150A1 (fr) * | 2021-03-26 | 2024-02-07 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Combinaison d'inhibiteur de la biosynthèse de la pyrimidine destinée à être utilisée dans le traitement d'infections virales |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4178306A (en) * | 1978-08-10 | 1979-12-11 | Parsons Jack L | Preparation of N-(phosphonoacetyl)-L-aspartic acid |
-
1993
- 1993-03-17 IL IL10509093A patent/IL105090A/en not_active IP Right Cessation
- 1993-03-18 AU AU39659/93A patent/AU3965993A/en not_active Abandoned
- 1993-03-18 IS IS3987A patent/IS3987A/is unknown
- 1993-03-18 CN CN93104593A patent/CN1080853A/zh active Pending
- 1993-03-18 CA CA002109435A patent/CA2109435C/fr not_active Expired - Fee Related
- 1993-03-18 MX MX9301527A patent/MX9301527A/es unknown
- 1993-03-18 BR BR9306123A patent/BR9306123A/pt not_active Application Discontinuation
- 1993-03-18 WO PCT/US1993/002432 patent/WO1993018763A1/fr not_active Application Discontinuation
- 1993-03-18 EP EP93909132A patent/EP0660710A1/fr not_active Withdrawn
- 1993-03-18 JP JP5516700A patent/JPH07507770A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IS3987A (is) | 1993-09-19 |
CN1080853A (zh) | 1994-01-19 |
AU3965993A (en) | 1993-10-21 |
MX9301527A (es) | 1994-02-28 |
IL105090A (en) | 1998-08-16 |
WO1993018763A1 (fr) | 1993-09-30 |
EP0660710A4 (fr) | 1995-03-02 |
IL105090A0 (en) | 1994-08-26 |
BR9306123A (pt) | 1997-08-26 |
CA2109435C (fr) | 1997-03-11 |
EP0660710A1 (fr) | 1995-07-05 |
JPH07507770A (ja) | 1995-08-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed | ||
MKLA | Lapsed |
Effective date: 20000320 |