CA2101074A1 - Procede de modification de l'extremite carboxyle de peptides contenant un residu proline en avant-derniere position de leur extremite carboxyle - Google Patents

Procede de modification de l'extremite carboxyle de peptides contenant un residu proline en avant-derniere position de leur extremite carboxyle

Info

Publication number
CA2101074A1
CA2101074A1 CA 2101074 CA2101074A CA2101074A1 CA 2101074 A1 CA2101074 A1 CA 2101074A1 CA 2101074 CA2101074 CA 2101074 CA 2101074 A CA2101074 A CA 2101074A CA 2101074 A1 CA2101074 A1 CA 2101074A1
Authority
CA
Canada
Prior art keywords
process according
pro
peptide
reaction
thr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2101074
Other languages
English (en)
Inventor
Stig Aasmul-Olsen
Kurt A. Christensen
Fred Widmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CARLBIOTECH Ltd AS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK37391A external-priority patent/DK37391D0/da
Application filed by Individual filed Critical Individual
Publication of CA2101074A1 publication Critical patent/CA2101074A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • C07K14/5855—Calcitonins at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/17—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced ascorbate as one donor, and incorporation of one atom of oxygen (1.14.17)
    • C12Y114/17003—Peptidylglycine monooxygenase (1.14.17.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CA 2101074 1991-03-01 1992-03-02 Procede de modification de l'extremite carboxyle de peptides contenant un residu proline en avant-derniere position de leur extremite carboxyle Abandoned CA2101074A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK37391A DK37391D0 (da) 1991-03-01 1991-03-01 Enzymatisk fremgangsmaade til c-terminal amidering af peptider og mellemprodukter til brug ved fremgangsmaaden
DK0373/91 1991-03-01
DK0676/91 1991-04-15
DK67691A DK67691D0 (da) 1991-03-01 1991-04-15 Enzymatisk fremgangsmaade til c-terminal modificering af peptider og mellemprodukter til brug ved fremgangsmaaden

Publications (1)

Publication Number Publication Date
CA2101074A1 true CA2101074A1 (fr) 1992-09-02

Family

ID=26063876

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2101074 Abandoned CA2101074A1 (fr) 1991-03-01 1992-03-02 Procede de modification de l'extremite carboxyle de peptides contenant un residu proline en avant-derniere position de leur extremite carboxyle

Country Status (7)

Country Link
EP (1) EP0573540A1 (fr)
JP (1) JPH06504676A (fr)
AU (1) AU1374992A (fr)
CA (1) CA2101074A1 (fr)
DK (1) DK67691D0 (fr)
IE (1) IE920664A1 (fr)
WO (1) WO1992015695A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10047857B4 (de) * 2000-09-27 2004-11-18 Universität Leipzig Verfahren zur selektiven biokatalytischen Modifizierung von Peptiden und Proteinen
JP6493216B2 (ja) * 2013-11-05 2019-04-03 味の素株式会社 ペプチドヒドラジド、ペプチドアミド及びペプチドチオエステルの製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319685B1 (en) * 1984-09-27 2001-11-20 Unigene Laboratories, Inc. Alpha-amidating enzyme compositions and processes for their production and use
JPS6229997A (ja) * 1985-04-08 1987-02-07 Sankyo Co Ltd Ｃ末端にプロリンアミドを有するペプチドの製法
US4652627A (en) * 1985-08-16 1987-03-24 Kempe Tomas G Calcitonin analogs with C-terminal D-amino acid substituents
US4687839A (en) * 1985-12-23 1987-08-18 Kempe Tomas G Calcitonin gene related peptide analogs with C-terminal D-amino acid substituents
JP2535398B2 (ja) * 1989-01-17 1996-09-18 サントリー株式会社 アミド化ペプチドの製造方法

Also Published As

Publication number Publication date
WO1992015695A1 (fr) 1992-09-17
IE920664A1 (en) 1992-09-09
JPH06504676A (ja) 1994-06-02
DK67691D0 (da) 1991-04-15
EP0573540A1 (fr) 1993-12-15
AU1374992A (en) 1992-10-06

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Legal Events

Date Code Title Description
FZDE Dead