CA2099609A1 - Quinobenzoxazine, quinobenzothiazine, and pyrido-acridine antineoplastic agents - Google Patents

Quinobenzoxazine, quinobenzothiazine, and pyrido-acridine antineoplastic agents

Info

Publication number
CA2099609A1
CA2099609A1 CA002099609A CA2099609A CA2099609A1 CA 2099609 A1 CA2099609 A1 CA 2099609A1 CA 002099609 A CA002099609 A CA 002099609A CA 2099609 A CA2099609 A CA 2099609A CA 2099609 A1 CA2099609 A1 CA 2099609A1
Authority
CA
Canada
Prior art keywords
oxo
fluoro
carboxylic acid
quino
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002099609A
Other languages
English (en)
French (fr)
Inventor
Daniel T. Chu
Jacob J. Plattner
Robert Hallas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2099609A1 publication Critical patent/CA2099609A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002099609A 1990-08-24 1991-08-23 Quinobenzoxazine, quinobenzothiazine, and pyrido-acridine antineoplastic agents Abandoned CA2099609A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57310290A 1990-08-24 1990-08-24
US573,102 1990-08-24

Publications (1)

Publication Number Publication Date
CA2099609A1 true CA2099609A1 (en) 1992-02-25

Family

ID=24290672

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002099609A Abandoned CA2099609A1 (en) 1990-08-24 1991-08-23 Quinobenzoxazine, quinobenzothiazine, and pyrido-acridine antineoplastic agents

Country Status (5)

Country Link
EP (1) EP0608215A1 (de)
CA (1) CA2099609A1 (de)
IE (1) IE912902A1 (de)
PT (1) PT98766B (de)
WO (1) WO1992003136A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0604181A1 (de) * 1992-12-21 1994-06-29 Eli Lilly And Company Antitumorpräparate und Behandlungsmethoden
US7507727B2 (en) 2003-04-07 2009-03-24 Cylene Pharmaceuticals, Inc. Substituted quinobenzoxazine analogs and methods of using thereof
CA2521810A1 (en) 2003-04-07 2004-10-28 Jeffrey P. Whitten Substituted quinobenzoxazine analogs
US7354916B2 (en) 2003-04-07 2008-04-08 Cylene Pharmaceuticals Substituted quinobenzoxazine analogs
US7163948B2 (en) 2003-04-07 2007-01-16 Cylene Pharmaceuticals, Inc. Heterocyclic substituted 1,4-dihydri-4ox9-1,8-naphthyridine analogs
US7652134B2 (en) 2004-09-17 2010-01-26 Cylene Pharmaceuticals, Inc. Methods for converting quinolone esters into quinolone amides
US7816406B2 (en) 2004-09-17 2010-10-19 Cylene Pharmaceuticals, Inc. Quinolone analogs

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA853071B (en) * 1984-04-26 1985-12-24 Abbott Lab Quino-quinoline antibacterial compounds
US4529725A (en) * 1984-04-26 1985-07-16 Abbott Laboratories 1-Pyridine substituted quino-benzothiazine
US4607032A (en) * 1984-04-26 1986-08-19 Abbott Laboratories Quino-benoxazine antibacterial compounds
US4540694A (en) * 1984-04-26 1985-09-10 Abbott Laboratories 1-Pyridine substituted quino-benoxazines and antibacterial use
US4542133A (en) * 1984-04-26 1985-09-17 Abbott Laboratories Methylenedioxy quino-benoxazine derivatives and antibacterial use
US4528285A (en) * 1984-04-26 1985-07-09 Abbott Laboratories Methylenedioxy quino-benzothiazine derivatives
US4533663A (en) * 1984-04-26 1985-08-06 Abbott Laboratories Quino-benzothiazine antibacterial compounds
US4689325A (en) * 1985-12-23 1987-08-25 Abbott Laboratories Isoxazolo-pyrido-phenoxazine and isothiazolo-pyrido-phenoxazine derivatives
DE3600891A1 (de) * 1986-01-15 1987-07-16 Bayer Ag 1,8-verbrueckte 4-chinolon-3-carbonsaeuren und diese enthaltende arzneimittel
FR2634483B2 (fr) * 1987-12-29 1994-03-04 Esteve Labor Dr Derives des acides 7-(1-azetidinyl)-1,4-dihydro-4-oxoquinoleine-3-carboxyliques, leur preparation et leur application en tant que medicaments

Also Published As

Publication number Publication date
IE912902A1 (en) 1992-02-26
PT98766A (pt) 1992-07-31
WO1992003136A1 (en) 1992-03-05
EP0608215A4 (de) 1993-11-11
EP0608215A1 (de) 1994-08-03
PT98766B (pt) 1999-01-29

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Legal Events

Date Code Title Description
FZDE Dead