CA2094341A1 - Methods for the use of spermidine/spermine n1-acetyltransferase as a prognostic indicator and/or tumor response marker - Google Patents

Methods for the use of spermidine/spermine n1-acetyltransferase as a prognostic indicator and/or tumor response marker

Info

Publication number
CA2094341A1
CA2094341A1 CA002094341A CA2094341A CA2094341A1 CA 2094341 A1 CA2094341 A1 CA 2094341A1 CA 002094341 A CA002094341 A CA 002094341A CA 2094341 A CA2094341 A CA 2094341A CA 2094341 A1 CA2094341 A1 CA 2094341A1
Authority
CA
Canada
Prior art keywords
spermine
spermidine
acetyltransferase
assay
induction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002094341A
Other languages
English (en)
French (fr)
Inventor
Carl W. Porter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Health Research Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2094341A1 publication Critical patent/CA2094341A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002094341A 1992-04-28 1993-04-19 Methods for the use of spermidine/spermine n1-acetyltransferase as a prognostic indicator and/or tumor response marker Abandoned CA2094341A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87509192A 1992-04-28 1992-04-28
US875,091 1992-04-28

Publications (1)

Publication Number Publication Date
CA2094341A1 true CA2094341A1 (en) 1993-10-29

Family

ID=25365191

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002094341A Abandoned CA2094341A1 (en) 1992-04-28 1993-04-19 Methods for the use of spermidine/spermine n1-acetyltransferase as a prognostic indicator and/or tumor response marker

Country Status (4)

Country Link
US (1) US5498522A (Direct)
EP (1) EP0568338A2 (Direct)
JP (1) JPH0662896A (Direct)
CA (1) CA2094341A1 (Direct)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674908A (en) * 1993-12-20 1997-10-07 Life Technologies, Inc. Highly packed polycationic ammonium, sulfonium and phosphonium lipids
US5650096A (en) * 1994-12-09 1997-07-22 Genzyme Corporation Cationic amphiphiles for intracellular delivery of therapeutic molecules
WO1996033703A2 (en) * 1995-04-25 1996-10-31 Oridigm Corporation S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy
JP3470901B2 (ja) * 1996-09-13 2003-11-25 ユニヴァーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイテッド Ｅｌｆ５Ａ生合成の抑制方法
AU2003231670B2 (en) * 1997-10-27 2006-06-08 Slil Biomedical Corporation Methods for modulating macrophage proliferation using polyamine analogs
US8198334B2 (en) * 1997-10-27 2012-06-12 Pathologica Llc Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
US7087648B1 (en) * 1997-10-27 2006-08-08 The Regents Of The University Of California Methods for modulating macrophage proliferation using polyamine analogs
JP3709078B2 (ja) * 1998-08-27 2005-10-19 ヤマサ醤油株式会社 ジアセチルポリアミンの測定法及びキット
PT1129064E (pt) 1998-11-12 2008-01-31 Invitrogen Corp Reagentes de transfecção
CA2362259A1 (en) * 1999-02-05 2000-08-10 Nicolaas M. J. Vermeulen Antizyme modulators and their use
HK1040993B (en) 1999-04-30 2006-11-10 Cellgate, Inc. Polyamines and their use in therapy
US6649587B1 (en) 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
US6482943B1 (en) * 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
AU4678300A (en) * 1999-04-30 2000-11-17 Slil Biomedical Corporation Novel polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
DK1247097T3 (da) * 2000-01-12 2004-11-29 Ventana Med Syst Inc Fremgangsmåde til bestemmelse af effektiviteten af cancerterapi
AU2002235126A1 (en) * 2000-11-08 2002-05-21 Slil Biomedical Corporation Novel polyamine analog-amino acid conjugates useful as anticancer agents
AU2002343609B2 (en) * 2001-11-16 2008-12-11 Als Therapy Development Foundation, Inc. Treatment of neurodegenerative disorders through the modulation of the polyamine pathway
WO2003050072A1 (en) 2001-12-07 2003-06-19 Slil Biomedical Corporation Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
JP2004189714A (ja) * 2002-12-09 2004-07-08 Rasanen Tiina-Liisa すい臓炎の治療と予防ならびに肝臓再生機能の誘導のための薬剤
CN102344950B (zh) * 2011-05-31 2015-08-26 上海拜瑞曼克生物科技有限公司 一种用于检测ssat底物的乙酰化代谢物的方法
WO2013033597A1 (en) 2011-09-02 2013-03-07 Temple University - Of The Commonwealth System Of Higher Education Ssat mrna translation repression and activation
US20160017054A1 (en) * 2013-01-30 2016-01-21 Biomark Technologies Inc. Spermidine/Spermine N1 - Acetyltransferase Antibodies As Anti-Cancer Drug Compounds
WO2016011203A1 (en) 2014-07-15 2016-01-21 Life Technologies Corporation Compositions with lipid aggregates and methods for efficient delivery of molecules to cells

Also Published As

Publication number Publication date
EP0568338A2 (en) 1993-11-03
US5498522A (en) 1996-03-12
JPH0662896A (ja) 1994-03-08
EP0568338A3 (Direct) 1994-03-30

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Legal Events

Date Code Title Description
FZDE Discontinued