CA2094270A1 - Derives de la xanthine - Google Patents

Derives de la xanthine

Info

Publication number
CA2094270A1
CA2094270A1 CA2094270A CA2094270A CA2094270A1 CA 2094270 A1 CA2094270 A1 CA 2094270A1 CA 2094270 A CA2094270 A CA 2094270A CA 2094270 A CA2094270 A CA 2094270A CA 2094270 A1 CA2094270 A1 CA 2094270A1
Authority
CA
Canada
Prior art keywords
group
formula
hydrogen atom
xanthine derivatives
different
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2094270A
Other languages
English (en)
Other versions
CA2094270C (fr
Inventor
Fumio Suzuki
Akio Ishii
Hiromi Nonaka
Nobuo Kosaka
Shunji Ichikawa
Junichi Shimada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2094270A1 publication Critical patent/CA2094270A1/fr
Application granted granted Critical
Publication of CA2094270C publication Critical patent/CA2094270C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Led Devices (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002094270A 1990-10-18 1991-10-17 Derives de la xanthine Expired - Fee Related CA2094270C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2/280171 1990-10-18
JP28017190 1990-10-18

Publications (2)

Publication Number Publication Date
CA2094270A1 true CA2094270A1 (fr) 1992-04-19
CA2094270C CA2094270C (fr) 1997-01-21

Family

ID=17621294

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002094270A Expired - Fee Related CA2094270C (fr) 1990-10-18 1991-10-17 Derives de la xanthine

Country Status (6)

Country Link
EP (1) EP0559893B1 (fr)
AT (1) ATE176470T1 (fr)
CA (1) CA2094270C (fr)
DE (1) DE69130869T2 (fr)
ES (1) ES2130138T3 (fr)
WO (1) WO1992006976A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2093403C (fr) * 1992-04-08 1999-08-10 Fumio Suzuki Agent de traitement de la maladie de parkinson
US5484920A (en) * 1992-04-08 1996-01-16 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for Parkinson's disease
CA2116967C (fr) * 1992-07-08 2003-08-19 Fumio Suzuki Antidepresseurs
TW252044B (fr) * 1992-08-10 1995-07-21 Boehringer Ingelheim Kg
JP2613355B2 (ja) * 1992-09-28 1997-05-28 協和醗酵工業株式会社 パーキンソン氏病治療剤
CA2112031A1 (fr) * 1992-12-24 1994-06-25 Fumio Suzuki Derives xanthine
WO1994025462A1 (fr) * 1993-05-03 1994-11-10 The United States Of America, Represented By The Derives de 1,3,7-trialkyl-xanthine substitues en position 8 utiles comme antagonistes de recepteurs d'adenosine a2 a selectivite
ES2070087B1 (es) * 1993-08-13 1996-02-16 Pfizer Derivados de indol
DE69526822T2 (de) * 1994-02-23 2003-01-23 Kyowa Hakko Kogyo Kk Xanthin-derivate
ATE325610T1 (de) 1997-09-05 2006-06-15 Kyowa Hakko Kogyo Kk Xanthinderivative zur behandlung von hirnischämie
DE69815554T2 (de) * 1998-01-05 2004-05-06 Eisai Co., Ltd. Purinderivate und antagonisten des adenosin-a2-rezeptors, welche zur vorsorge oder heilung von diabetes dienen
WO2001032182A1 (fr) * 1999-10-29 2001-05-10 Kyowa Hakko Kogyo Co., Ltd Remedes contre les troubles de l'alimentation
FR2804958B1 (fr) * 2000-02-15 2005-07-08 Hoechst Marion Roussel Inc Derives de xanthine, leur procede de preparation et les intermediaires de ce procede, leur application comme medicament et les compositions pharmaceutiques les renfermant
EP2942082B1 (fr) 2002-01-28 2019-03-06 Kyowa Hakko Kogyo Co., Ltd Antagonistes des récepteurs a2a pour utilisation dans le traitement des troubles du mouvement
CA2530649A1 (fr) * 2003-06-27 2005-01-06 Kyowa Hakko Kogyo Co., Ltd. Agent antiepileptique
EP1709967A4 (fr) * 2004-01-28 2010-09-15 Kyowa Hakko Kirin Co Ltd Medicament contre la migraine
ES2273599B1 (es) 2005-10-14 2008-06-01 Universidad De Barcelona Compuestos para el tratamiento de la fibrilacion auricular.
JP2010511628A (ja) * 2006-12-01 2010-04-15 ギリアード・パロ・アルト・インコーポレイテッド Ａ２ａアデノシン受容体アンタゴニスト
KR20090094465A (ko) * 2006-12-22 2009-09-07 슈바르츠 파르마 악티엔게젤샤프트 선택적 ａ2ａ 수용체 안타고니스토로서의 8-알키닐잔틴 유도체
RU2477726C1 (ru) * 2011-10-18 2013-03-20 Общество С Ограниченной Ответственностью "Ньювак" (Ооо "Ньювак") Замещенные феноксиуксусные кислоты, их эфиры и амиды, включающие 2,6-диоксо-2,3,6,7-тетрагидро-1н-пурин-8-иловый фрагмент, - антагонисты аденозинового a2a рецептора и их применение
WO2020125779A1 (fr) * 2018-12-21 2020-06-25 Sunshine Lake Pharma Co., Ltd. Dérivés de styryl xanthine substitués en position 8 et leurs utilisations
CN111072663B (zh) * 2019-12-12 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途
CN111018856B (zh) * 2019-12-12 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69033614T2 (de) * 1989-10-20 2001-04-19 Kyowa Hakko Kogyo Kk Kondensierte Purinderivate

Also Published As

Publication number Publication date
EP0559893A1 (fr) 1993-09-15
ATE176470T1 (de) 1999-02-15
EP0559893B1 (fr) 1999-02-03
DE69130869T2 (de) 1999-06-10
EP0559893A4 (en) 1994-07-06
ES2130138T3 (es) 1999-07-01
DE69130869D1 (en) 1999-03-18
WO1992006976A1 (fr) 1992-04-30
CA2094270C (fr) 1997-01-21

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Legal Events

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MKLA Lapsed