CA2094259A1 - Fragments therapeutiques du facteur de von willebrand - Google Patents

Fragments therapeutiques du facteur de von willebrand

Info

Publication number
CA2094259A1
CA2094259A1 CA002094259A CA2094259A CA2094259A1 CA 2094259 A1 CA2094259 A1 CA 2094259A1 CA 002094259 A CA002094259 A CA 002094259A CA 2094259 A CA2094259 A CA 2094259A CA 2094259 A1 CA2094259 A1 CA 2094259A1
Authority
CA
Canada
Prior art keywords
polypeptide
fragment
sequence
residue
von willebrand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002094259A
Other languages
English (en)
Inventor
Zaverio M. Ruggeri
Jerry L. Ware
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2094259A1 publication Critical patent/CA2094259A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002094259A 1990-10-17 1991-10-17 Fragments therapeutiques du facteur de von willebrand Abandoned CA2094259A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US600,183 1984-04-13
US60018390A 1990-10-17 1990-10-17
US61300490A 1990-11-13 1990-11-13
US613,004 1990-11-13
US67552991A 1991-03-27 1991-03-27
US675,529 1991-03-27
PCT/US1991/007756 WO1992006999A1 (fr) 1990-10-17 1991-10-17 Fragments therapeutiques du factor de von willebrand

Publications (1)

Publication Number Publication Date
CA2094259A1 true CA2094259A1 (fr) 1992-04-18

Family

ID=27416797

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002094259A Abandoned CA2094259A1 (fr) 1990-10-17 1991-10-17 Fragments therapeutiques du facteur de von willebrand

Country Status (4)

Country Link
JP (1) JPH06502541A (fr)
AU (1) AU9069591A (fr)
CA (1) CA2094259A1 (fr)
WO (1) WO1992006999A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686901A1 (fr) * 1992-01-31 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux polypeptides antithrombotiques, leur preparation et compositions pharmaceutiques les contenant.
IL109383A0 (en) * 1993-04-23 1994-07-31 Bio Technology General Corp Method for enhancing thrombolysis
AU1382595A (en) * 1994-01-07 1995-08-01 Novo Nordisk A/S Factor viii derivatives
JP2021519280A (ja) * 2018-03-21 2021-08-10 バクスアルタ インコーポレイテッド クロマトグラフィー法によるvwfとvwfプロペプチドの分離

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683291A (en) * 1985-10-28 1987-07-28 Scripps Clinic And Research Foundation Platelet binding inhibitors

Also Published As

Publication number Publication date
WO1992006999A1 (fr) 1992-04-30
AU9069591A (en) 1992-05-20
JPH06502541A (ja) 1994-03-24

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Legal Events

Date Code Title Description
FZDE Dead