CA2089166A1 - Derives benzanilide et leur utilisation comme agents anti-antherosclerotiques - Google Patents

Derives benzanilide et leur utilisation comme agents anti-antherosclerotiques

Info

Publication number
CA2089166A1
CA2089166A1 CA002089166A CA2089166A CA2089166A1 CA 2089166 A1 CA2089166 A1 CA 2089166A1 CA 002089166 A CA002089166 A CA 002089166A CA 2089166 A CA2089166 A CA 2089166A CA 2089166 A1 CA2089166 A1 CA 2089166A1
Authority
CA
Canada
Prior art keywords
decyloxybenzamido
benzoate
group containing
carbon atoms
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002089166A
Other languages
English (en)
Inventor
Andrew William Bridge
David John Lythgoe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Rorer Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2089166A1 publication Critical patent/CA2089166A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/63—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
CA002089166A 1990-08-13 1991-08-13 Derives benzanilide et leur utilisation comme agents anti-antherosclerotiques Abandoned CA2089166A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9017710.6 1990-08-13
GB909017710A GB9017710D0 (en) 1990-08-13 1990-08-13 New compositions of matter

Publications (1)

Publication Number Publication Date
CA2089166A1 true CA2089166A1 (fr) 1992-02-14

Family

ID=10680575

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002089166A Abandoned CA2089166A1 (fr) 1990-08-13 1991-08-13 Derives benzanilide et leur utilisation comme agents anti-antherosclerotiques

Country Status (10)

Country Link
EP (1) EP0543884A1 (fr)
JP (1) JPH06500083A (fr)
AU (1) AU8337891A (fr)
CA (1) CA2089166A1 (fr)
GB (1) GB9017710D0 (fr)
IE (1) IE912849A1 (fr)
IL (1) IL99160A0 (fr)
PT (1) PT98665A (fr)
WO (1) WO1992003408A1 (fr)
ZA (1) ZA916339B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2894445B2 (ja) * 1997-02-12 1999-05-24 日本たばこ産業株式会社 Ｃｅｔｐ活性阻害剤として有効な化合物
JP2006520810A (ja) 2003-03-17 2006-09-14 日本たばこ産業株式会社 Ｓ−［２−（［［１−（２−エチルブチル）シクロヘキシル］カルボニル］アミノ）フェニル］２−メチルプロパンチオエートの経口吸収性を増加させる方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU79008A1 (de) * 1978-02-03 1979-09-06 Byk Gulden Lomberg Chem Fab W-(n-alkyl-n-benzoyl-amino)-phenylalkansaeuren,ihre verwendung und herstellung sowie sie enthaltende arzneimittel
IT1196348B (it) * 1984-11-29 1988-11-16 Italfarmaco Spa Composti ad attivita'antiinfiammatoria
LU86258A1 (fr) * 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
US4882357A (en) * 1988-07-15 1989-11-21 Warner-Lambert Company Novel N-(substituted-phenyl)-5-(substituted-2,5-dimethylphenoxy)-2,2-dimethylpentanamides
GB8921792D0 (en) * 1989-09-27 1989-11-08 May & Baker Ltd New compositions of matter

Also Published As

Publication number Publication date
ZA916339B (en) 1992-05-27
IL99160A0 (en) 1992-07-15
JPH06500083A (ja) 1994-01-06
EP0543884A1 (fr) 1993-06-02
GB9017710D0 (en) 1990-09-26
IE912849A1 (en) 1992-02-26
WO1992003408A1 (fr) 1992-03-05
AU8337891A (en) 1992-03-17
PT98665A (pt) 1992-06-30

Similar Documents

Publication Publication Date Title
KR100276182B1 (ko) 2-시아노-3-히드록시엔아미드, 그의 제조방법, 그를 함유한 제약조성물 및 의약으로서의 그의 용도
CA1116611A (fr) Derives de l'imidazole utilise comme anticonvulsivant
EP1149063A2 (fr) Derives d'acide ureido-thiobutyrique comme agonistes ppar
EP0131221B1 (fr) Thioéthers, procédé pour leur préparation ainsi que der médicaments contenant ces composés
US5240960A (en) 3-cycloalkyl-propanamides
US3120551A (en) 5-(4-biphenylyl)-3-methylvaleric acid and functional derivatives thereof
EP0415566A1 (fr) Composés hétérocycliques, procédé pour leur production et compositions pharmaceutiques les contenant
AU738857B2 (en) Colchicine and thiocolchicine derivatives with antiflammatory and muscle relaxant activities
GB1576007A (en) Hypolipidaemic compositions
JPH0393787A (ja) 抗ウイルス活性を有する薬剤、燐脂質誘導体及びその製造方法
CA2089166A1 (fr) Derives benzanilide et leur utilisation comme agents anti-antherosclerotiques
GB1576841A (en) Substituted n-acyl phenylamine compounds having hypolipidaemic activity
EP0091761A2 (fr) Dérivés de thiazolidine et leur préparation
JPS6316386B2 (fr)
EP0324472B1 (fr) Dérivés de cétènedithioacétals et procédés pour leur production et compositions les contenant
EP0253370B1 (fr) Dérivés de 1,3,5-trithiane
CA2089151A1 (fr) Derives benzamide
US4600540A (en) Benzoylpropionic acid derivatives
GB2398779A (en) 1,8-dihydroxyanthraquinone-6-carboxamide derivatives as modulators of IL-10 production for treatment of autoimmune or inflammatory conditions
GB2398780A (en) 1,8-dihydroxyanthraquinone-6-carboxamide derivatives as inhibitors of T-cell proliferation for treatment of autoimmune or inflammatory conditions
CA1144172A (fr) Nouveaux derives de 1-¬(2-mercaptocycloalkyl) carbonyl|-l-proline; procede pour les fabriquer; produits intermediaires pour leur synthese, et applications comme agents contre l'hypertension
WO1996011901A1 (fr) NOUVEAUX ACIDES α,α,α',α'-TETRACHLORODICARBOXYLIQUES, LEUR PROCEDE DE PREPARATION ET MEDICAMENTS LES CONTENANT
CA1105053A (fr) Sulfamido acetyleniques de benzamides utilisables en therapeutique
EP0005141A1 (fr) Dérivés du benzothiopyranne, leur préparation et compositions pharmaceutiques les contenant
EP0319644A2 (fr) Dérivés alcoylés d'amides, leur utilisation et compositions pharmaceutiques les contenant

Legal Events

Date Code Title Description
FZDE Discontinued