CA2081838A1 - Methodes et compositions servant a la permeabilisation reversible de la barriere hemato-encephalique - Google Patents

Methodes et compositions servant a la permeabilisation reversible de la barriere hemato-encephalique

Info

Publication number
CA2081838A1
CA2081838A1 CA002081838A CA2081838A CA2081838A1 CA 2081838 A1 CA2081838 A1 CA 2081838A1 CA 002081838 A CA002081838 A CA 002081838A CA 2081838 A CA2081838 A CA 2081838A CA 2081838 A1 CA2081838 A1 CA 2081838A1
Authority
CA
Canada
Prior art keywords
cell wall
wall
ion
eubacteria
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002081838A
Other languages
English (en)
Inventor
Alexander Tomasz
Elaine Tuomanen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rockefeller University
Original Assignee
Rockefeller University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP19910908404 priority Critical patent/EP0527810A4/en
Priority to PCT/US1991/002533 priority patent/WO1991016064A1/fr
Priority to CA002080376A priority patent/CA2080376A1/fr
Application filed by Rockefeller University filed Critical Rockefeller University
Priority to CA002081838A priority patent/CA2081838A1/fr
Publication of CA2081838A1 publication Critical patent/CA2081838A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002081838A 1990-04-13 1992-10-30 Methodes et compositions servant a la permeabilisation reversible de la barriere hemato-encephalique Abandoned CA2081838A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP19910908404 EP0527810A4 (en) 1990-04-13 1991-04-12 Methods and compositions for reversibly permeabilizing the blood brain barrier
PCT/US1991/002533 WO1991016064A1 (fr) 1990-04-13 1991-04-12 Procedes et compositions permettant de rendre permeable, de maniere reversible, la barriere hemato-encephalique
CA002080376A CA2080376A1 (fr) 1990-04-13 1991-04-12 Methodes et compositions permettant une permeabilisation reversible de la barriere hemato-encephalique
CA002081838A CA2081838A1 (fr) 1990-04-13 1992-10-30 Methodes et compositions servant a la permeabilisation reversible de la barriere hemato-encephalique

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50931990A 1990-04-13 1990-04-13
US51555290A 1990-04-27 1990-04-27
CA002081838A CA2081838A1 (fr) 1990-04-13 1992-10-30 Methodes et compositions servant a la permeabilisation reversible de la barriere hemato-encephalique

Publications (1)

Publication Number Publication Date
CA2081838A1 true CA2081838A1 (fr) 1994-05-01

Family

ID=27169231

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002080376A Abandoned CA2080376A1 (fr) 1990-04-13 1991-04-12 Methodes et compositions permettant une permeabilisation reversible de la barriere hemato-encephalique
CA002081838A Abandoned CA2081838A1 (fr) 1990-04-13 1992-10-30 Methodes et compositions servant a la permeabilisation reversible de la barriere hemato-encephalique

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002080376A Abandoned CA2080376A1 (fr) 1990-04-13 1991-04-12 Methodes et compositions permettant une permeabilisation reversible de la barriere hemato-encephalique

Country Status (3)

Country Link
EP (1) EP0527810A4 (fr)
CA (2) CA2080376A1 (fr)
WO (1) WO1991016064A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0740548B1 (fr) * 1994-02-28 2002-12-04 Nanopharm AG Systeme de ciblage d'un medicament, procede de preparation et utilisation de ce medicament

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4866042A (en) * 1987-11-18 1989-09-12 Neuwelt Edward A Method for the delivery of genetic material across the blood brain barrier

Also Published As

Publication number Publication date
WO1991016064A1 (fr) 1991-10-31
EP0527810A1 (fr) 1993-02-24
EP0527810A4 (en) 1993-06-16
CA2080376A1 (fr) 1991-10-14

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Legal Events

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