CA2060198A1 - Methode de preparation de vaccins contre les virus a arn - Google Patents
Methode de preparation de vaccins contre les virus a arnInfo
- Publication number
- CA2060198A1 CA2060198A1 CA2060198A CA2060198A CA2060198A1 CA 2060198 A1 CA2060198 A1 CA 2060198A1 CA 2060198 A CA2060198 A CA 2060198A CA 2060198 A CA2060198 A CA 2060198A CA 2060198 A1 CA2060198 A1 CA 2060198A1
- Authority
- CA
- Canada
- Prior art keywords
- cells
- rna viruses
- vaccines against
- virus
- against rna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
Abstract
On prépare un vaccin contre un virus de l'ARN, pouvant être un picornavirus, un orthomyxovirus ou un rétrovirus, par contamination de cellules hôtes à l'aide dudit virus, incubation des cellules contaminées pendant une période de temps donné, et à une température insuffisante pour obtenir la lyse des cellules, par séparation des noyaux des cellules intactes de leur fraction cytoplasmique, et par stabilisation des protéines antigéniques virales se trouvant dans la fraction cytoplasmique, les protéines stabilisées produisant le composant actif du vaccin.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898913665A GB8913665D0 (en) | 1989-06-14 | 1989-06-14 | Method of preparing vaccines against rna viruses |
GB8913665.9 | 1989-06-14 | ||
PCT/GB1990/000905 WO1990015622A1 (fr) | 1989-06-14 | 1990-06-12 | Procede de preparation de vaccins contre les virus lies a l'arn |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2060198A1 true CA2060198A1 (fr) | 1990-12-15 |
CA2060198C CA2060198C (fr) | 2000-05-02 |
Family
ID=10658419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002060198A Expired - Fee Related CA2060198C (fr) | 1989-06-14 | 1990-06-12 | Methode de preparation de vaccins contre les virus a arn |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0477240B1 (fr) |
JP (1) | JP2973372B2 (fr) |
AT (1) | ATE126702T1 (fr) |
AU (1) | AU637114B2 (fr) |
CA (1) | CA2060198C (fr) |
DE (1) | DE69021879T2 (fr) |
GB (1) | GB8913665D0 (fr) |
WO (1) | WO1990015622A1 (fr) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1267591A (en) * | 1969-02-26 | 1972-03-22 | Nat Res Dev | Antigenic materials |
IL68219A0 (en) * | 1982-03-24 | 1983-06-15 | Univ Birmingham | Vaccine against dna viruses |
NZ225583A (en) * | 1987-08-06 | 1991-07-26 | Merck & Co Inc | Process for purifying hepatitis a virions (hav) |
-
1989
- 1989-06-14 GB GB898913665A patent/GB8913665D0/en active Pending
-
1990
- 1990-06-12 CA CA002060198A patent/CA2060198C/fr not_active Expired - Fee Related
- 1990-06-12 EP EP90909343A patent/EP0477240B1/fr not_active Expired - Lifetime
- 1990-06-12 AU AU58326/90A patent/AU637114B2/en not_active Ceased
- 1990-06-12 JP JP2508641A patent/JP2973372B2/ja not_active Expired - Fee Related
- 1990-06-12 AT AT90909343T patent/ATE126702T1/de not_active IP Right Cessation
- 1990-06-12 WO PCT/GB1990/000905 patent/WO1990015622A1/fr active IP Right Grant
- 1990-06-12 DE DE69021879T patent/DE69021879T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2973372B2 (ja) | 1999-11-08 |
DE69021879T2 (de) | 1996-04-04 |
DE69021879D1 (de) | 1995-09-28 |
EP0477240A1 (fr) | 1992-04-01 |
AU5832690A (en) | 1991-01-08 |
GB8913665D0 (en) | 1989-08-02 |
EP0477240B1 (fr) | 1995-08-23 |
ATE126702T1 (de) | 1995-09-15 |
AU637114B2 (en) | 1993-05-20 |
CA2060198C (fr) | 2000-05-02 |
JPH04506209A (ja) | 1992-10-29 |
WO1990015622A1 (fr) | 1990-12-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2684792A (en) | Porcine reproductive respiratory syndrome vaccine and diagnostic | |
MY117686A (en) | Infectious clones of rna viruses and vaccines and diagnostic assays derived thereof | |
DE3853422T2 (de) | HIV-3-Retrovirus und seine Verwendung. | |
CA2102918A1 (fr) | Vaccin genetique anti-virus de l'immunodeficience | |
EA200000528A1 (ru) | Способ получения вакцин для предупреждения патогенных эффектов, связанных с ретровирусной инфекцией | |
ZA923321B (en) | Recombinant avipox virus,the culture of cells infected by this virus and vaccines for poultry derived from this virus | |
EP0232798A3 (fr) | Mutants de virus pseudorabique, vaccins les contenant, leurs procédés de préparation, ainsi que méthodes pour leur utilisation | |
WO2004004761A3 (fr) | Particule virale d'adjuvant | |
EP0261940A3 (fr) | Vaccins pseudorabiques et vecteurs d'ADN pour recombiner avec les poxvirus | |
TW377373B (en) | Recombinant raccoon pox viruses and their use as an effective vaccine against feline infectious peritonitis virus disease | |
ATE101200T1 (de) | Impfstoffe gegen menschliche respiratorische viren. | |
DK0480949T3 (da) | Fremstilling af virus og oprensning af virale kappeproteiner til vaccineanvendelse | |
IE781880L (en) | Immunogenic herpes virus subunit | |
WO2001016163A3 (fr) | Melange peptidique et vaccin contre une infection virale chronique | |
EP0019218A3 (en) | Influenza virus vaccines, process for preparing them, process for propagating influenza viruses and cell culture inoculated with influenza virus | |
WO1994013812A3 (fr) | Nouveaux genes de l'entomopoxvirus, nouvelles proteines et leurs procedes d'utilisation | |
IE870507L (en) | Bovine virus diarrhea and hog cholera vaccines | |
CA2060198A1 (fr) | Methode de preparation de vaccins contre les virus a arn | |
CA2116355A1 (fr) | Mutants infectieux du virus de la rhinotracheite bovine et vaccins | |
DK8789A (da) | Fremgangsmaade til fremstilling af modificerede, staerkt afsvaekkede rna-virusstammer samt vaccine og dens anvendelse | |
WO2001027282A8 (fr) | Particules virales comportant des epitopes internes exogenes | |
WO1992014818A3 (fr) | Systeme d'expression d'entomopoxvirus comprenant des sequences de spheroïdine ou de thymidine-kinase | |
Danes et al. | Study of the possibility of preparing a vaccine against tick-borne encephalitis, using tissue culture methods. II. The inactivation by formaldehyde of the tickborne encephalitis virus in liquids prepared from tissue cultures. Immunogenic properties | |
Rice | Synthetic bovine parainfluenza virus. | |
Weremowicz et al. | Analysis of an equine influenza virus purification. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |