DE69021879D1 - Verfahren zur herstellung von impfstoffen gegen rna-virus. - Google Patents

Verfahren zur herstellung von impfstoffen gegen rna-virus.

Info

Publication number
DE69021879D1
DE69021879D1 DE69021879T DE69021879T DE69021879D1 DE 69021879 D1 DE69021879 D1 DE 69021879D1 DE 69021879 T DE69021879 T DE 69021879T DE 69021879 T DE69021879 T DE 69021879T DE 69021879 D1 DE69021879 D1 DE 69021879D1
Authority
DE
Germany
Prior art keywords
cells
rna virus
virus
production
against rna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69021879T
Other languages
English (en)
Other versions
DE69021879T2 (de
Inventor
Gordon Skinner
Alexander Buchan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Birmingham
Original Assignee
University of Birmingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Birmingham filed Critical University of Birmingham
Application granted granted Critical
Publication of DE69021879D1 publication Critical patent/DE69021879D1/de
Publication of DE69021879T2 publication Critical patent/DE69021879T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE69021879T 1989-06-14 1990-06-12 Verfahren zur herstellung von impfstoffen gegen rna-virus. Expired - Fee Related DE69021879T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898913665A GB8913665D0 (en) 1989-06-14 1989-06-14 Method of preparing vaccines against rna viruses
PCT/GB1990/000905 WO1990015622A1 (en) 1989-06-14 1990-06-12 Method of preparing vaccines against rna viruses

Publications (2)

Publication Number Publication Date
DE69021879D1 true DE69021879D1 (de) 1995-09-28
DE69021879T2 DE69021879T2 (de) 1996-04-04

Family

ID=10658419

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69021879T Expired - Fee Related DE69021879T2 (de) 1989-06-14 1990-06-12 Verfahren zur herstellung von impfstoffen gegen rna-virus.

Country Status (8)

Country Link
EP (1) EP0477240B1 (de)
JP (1) JP2973372B2 (de)
AT (1) ATE126702T1 (de)
AU (1) AU637114B2 (de)
CA (1) CA2060198C (de)
DE (1) DE69021879T2 (de)
GB (1) GB8913665D0 (de)
WO (1) WO1990015622A1 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1267591A (en) * 1969-02-26 1972-03-22 Nat Res Dev Antigenic materials
ATE39054T1 (de) * 1982-03-24 1988-12-15 Univ Birmingham Dns viren-vakzin.
NZ225583A (en) * 1987-08-06 1991-07-26 Merck & Co Inc Process for purifying hepatitis a virions (hav)

Also Published As

Publication number Publication date
WO1990015622A1 (en) 1990-12-27
JPH04506209A (ja) 1992-10-29
DE69021879T2 (de) 1996-04-04
JP2973372B2 (ja) 1999-11-08
AU5832690A (en) 1991-01-08
CA2060198C (en) 2000-05-02
CA2060198A1 (en) 1990-12-15
EP0477240A1 (de) 1992-04-01
ATE126702T1 (de) 1995-09-15
GB8913665D0 (en) 1989-08-02
AU637114B2 (en) 1993-05-20
EP0477240B1 (de) 1995-08-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee