CA2050584A1 - Megakaryocyte growth promoting activity - Google Patents

Megakaryocyte growth promoting activity

Info

Publication number
CA2050584A1
CA2050584A1 CA002050584A CA2050584A CA2050584A1 CA 2050584 A1 CA2050584 A1 CA 2050584A1 CA 002050584 A CA002050584 A CA 002050584A CA 2050584 A CA2050584 A CA 2050584A CA 2050584 A1 CA2050584 A1 CA 2050584A1
Authority
CA
Canada
Prior art keywords
mgpa
csf
cells
megakaryocyte
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002050584A
Other languages
English (en)
French (fr)
Inventor
Barbara W. Grant
Kenneth G. Mann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Vermont and State Agricultural College
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2050584A1 publication Critical patent/CA2050584A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fodder In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002050584A 1989-04-03 1990-04-02 Megakaryocyte growth promoting activity Abandoned CA2050584A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33265189A 1989-04-03 1989-04-03
US332,651 1989-04-03
PCT/US1990/001725 WO1990012108A1 (en) 1989-04-03 1990-04-02 Megakaryocyte growth promoting activity

Publications (1)

Publication Number Publication Date
CA2050584A1 true CA2050584A1 (en) 1990-10-04

Family

ID=23299216

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002050584A Abandoned CA2050584A1 (en) 1989-04-03 1990-04-02 Megakaryocyte growth promoting activity

Country Status (5)

Country Link
EP (1) EP0466780A4 (ja)
JP (1) JPH04506513A (ja)
AU (1) AU641645B2 (ja)
CA (1) CA2050584A1 (ja)
WO (1) WO1990012108A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6433142B1 (en) * 1989-08-08 2002-08-13 Genetics Institute, Llc Megakaryocyte stimulating factors
AU8868891A (en) * 1990-10-12 1992-05-20 Amgen, Inc. Megakaryocyte maturation factors
ATE170559T1 (de) * 1991-05-31 1998-09-15 Genentech Inc Behandlung der hiv-assoziierten immun- thrombopenie purpura
CA2112492A1 (en) * 1991-06-28 1993-01-07 Hava Avraham A differentiated megakaryocyte line producing novel megakaryocyte differentiation factors
US5250732A (en) * 1991-07-18 1993-10-05 Genentech, Inc. Ketamine analogues for treatment of thrombocytopenia
CN1107891A (zh) * 1994-03-04 1995-09-06 上海贝特生物技术有限公司 人促巨核细胞生成素及其分离纯化和基因克隆方法及应用
SK166695A3 (en) * 1994-03-31 1997-02-05 Amgen Inc Mgdf polypeptide for stimulating growth and megakaryocyte differentiation
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
TW497972B (en) * 1995-06-08 2002-08-11 Kirin Brewery Stable thrombopoietin (TPO)-containing lyophilized compositions
RU2482870C1 (ru) * 2012-02-27 2013-05-27 Федеральное государственное бюджетное учреждение "Российский онкологический научный центр имени Н.Н. Блохина" Российской академии медицинских наук (ФГБУ "РОНЦ им. Н.Н. Блохина" РАМН) Средство, индуцирующее дифференцировку стволовых кроветворных клеток в тромбоциты

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695542A (en) * 1983-10-04 1987-09-22 Dnax Research Institute Of Molecular And Cellular Biology, Inc. cDNA clones coding for polypeptides exhibiting multi-lineage cellular growth factor activity
DK15492A (da) * 1989-08-08 1992-02-07 Genentech Inst Inc En megakaryocytopoietisk faktor

Also Published As

Publication number Publication date
AU5405890A (en) 1990-11-05
WO1990012108A1 (en) 1990-10-18
AU641645B2 (en) 1993-09-30
EP0466780A1 (en) 1992-01-22
EP0466780A4 (en) 1992-08-26
JPH04506513A (ja) 1992-11-12

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Legal Events

Date Code Title Description
FZDE Dead