CA2046996A1 - Broad spectrum antimicrobial system for hard surface cleaners - Google Patents
Broad spectrum antimicrobial system for hard surface cleanersInfo
- Publication number
- CA2046996A1 CA2046996A1 CA002046996A CA2046996A CA2046996A1 CA 2046996 A1 CA2046996 A1 CA 2046996A1 CA 002046996 A CA002046996 A CA 002046996A CA 2046996 A CA2046996 A CA 2046996A CA 2046996 A1 CA2046996 A1 CA 2046996A1
- Authority
- CA
- Canada
- Prior art keywords
- cleaner
- broad spectrum
- gram
- hydrotrope
- hard surface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/18—Hydrocarbons
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
NOVEL BROAD SPECTRUM ;ANTIMICROBTAL
SYSTEM FOR HARD SURFACE CLEANERS
ABSTRACT OF THE DISCLOSURE
A liquid hard surface cleaner having broad spectrum disinfectancy activity in an alkaline based on a synergistic effect between pine oil, a chelating agent and a hydrotrope at a pH of 8 to 12. The cleaner has disinfectanay activity against both gram positive and gram negative organisms.
SYSTEM FOR HARD SURFACE CLEANERS
ABSTRACT OF THE DISCLOSURE
A liquid hard surface cleaner having broad spectrum disinfectancy activity in an alkaline based on a synergistic effect between pine oil, a chelating agent and a hydrotrope at a pH of 8 to 12. The cleaner has disinfectanay activity against both gram positive and gram negative organisms.
Description
31, 326 NOVEI. E3RO~D 8P~C~R~M ~rIMIcRoBIAL
Thi~ i,veIlltion r~31ate~ to an alkaline basQd ~urfa(:e cleaner having broa~ spectrUDI di~3in~ecta~ ia~d ao~tailling pi~ oilO
A ~umber of pin~ oil aontaining s~lealler3 ~re knowIl ~Eor cleani~g h~rd ~urf~Ge~, i.e. poroelain, enaDIel ~ plastic~ ate~ and tha li~e. æu~h clean~rs are ~ffeative ~or oleaning greasy soil, and in combinatioll with Gertai~ ~urfactant~3 th2y have been ei~Eective i~l cle~ni~g grimy ~oil from su:cfac:e.
however, pi~e oil b.sed oleaner3 hurQ ~ot be~ll found to ha~e broad spe¢trum anti~icrobial aotivity since they are o~ly effeotiYe again~t gra~ negative organi~m~ and ~ot against gram posiltive oxga~ism U~ 8 sauater~ary ammonium c:o~psunas are pr~ ent. Th~ use o~ quaternary ~o~polma~ in a oleaner i~ ~ot desirable 5illl:e the~e compound~ have a r~umber of unde~irable gualitie~, A
higll r~ lue is le~t o~ the surfaae after c:lea~i~gO I~
addiltiont quaternary ammo~ium co~npou~d are too tonic for this U~38 ~nd are highly irritati:llg to the skin, eye~, etc.
Ill IJnit d 8tate~ Patent ~umber 4,867,898, it is di~closed t~hat a broad spç30trum pine oil d:L~infec:ta~ay liquid cleaner, efiEeo1:ive against both gram positive and gram negativ0 orga~lism~, aould be ~ 2 ~ J~
obtained by a co~bination of pi~e oil and oil solllble organic aaids a~ a pH of O to 6. ~lthough this formulation ~as a~ efiE6!~tive, broad 8peCtrllm~
~isi~a~ecting c:leanzr, it ~uf~erad frs:m the di3advantage that it was hars~ to the satin~ eye5 and also to the surPaGes to be cleaner~ Tlhus, this clea~er wa~ not entireïy satisfactory ~or general ~leani~g U5e~o It i~ kno~n that alkaline ba~sed pine oil ~yYtem3 are ~ot so harsh. ~Iowever, it has not 1~ heretofore been pos~ible to obtain ~n alkallne based pine oil cleaner haviny broad spec:tsum di~in~ectallc:y against both gram positive and gr~ negative organism~.
8uch formulations were ef:Eeati~e only agai:nst gram negative ors~anism3.
It is there~ore a~ obj Qat o~ this invention to provide a pine oil con1:aini~g hard ~urface cleaner that has broad spectrum disinectancy, but is not harsh to skin, eyes and the surfa~es bei~g ~lea~ed.
A ~urther objeat is to o~tain a pi~e oil aontaini~g hard ~Ur~Ge ~leaner~ in an alkali~e medium having broad spectrum disi~feotanc~0 We ha~e now foun~ that pi~e oil becomes a true broad spectrum disi~fec~ant in the prese~ce of small amou~ts~ chelati~g agent and hydrotrope in a alkaline based e~ulsion produc The raw material in the amounts thereo~ are non-toxi~, non-irritating, ~o medici~al odor, compatible with pi~e oil i~ a properly emulsi~ied system~ co~Yenient and easy to use i~ a v riety o~ consumer and indu~trial hard surface disinfe~tant cleaning pro~u~ts~
Numerou~ household, nstitutional, industrial, and agricultuxal surfaces becom~
cont2minated with bo~h gram negative and gram posit v~
baateria. The presen~e o~ pine sil, tetraso~ium EDTA, and ~odi~m xylene sulfonate in an al~aline based .
cleaning preparation will totally diainfect that hard ~urface and deodorize the room without harm to human~
an~ animals.
The ingredient~ and amount~ that mak~ up tha haxd ~urface cleaner of the pre~ent inve~tion ars listed in Table I belo~. It will be under~tood that the listing of chelating agent~ and hydrotropes i~
e~emplary and not in¢lu~ive.
~ 9 ~
TABI.13 I
PINE: OIL DISINF}:C:TING COMPOæITION
WIT~ CON_E~TRA~rION RANGES
Pi~le Oil 10 . 00 to 30 . Ob Tetra~odium EDTA O . 01 to 5 . 00 Sodium Xyle~-e ~;ul~onate 1. 00 to 15 . 00 I~opropallol 3 . 00 to 10 . 00 Pareth-25 Sulfate 2 . 00 to 16 . 00 Sodiu~ C14-C16 Ole~in sul~onate 2 . 00 to 16 . 00 Li~3ar AlkylBe~ze~l~ æul~o~ate 2.00 to 16.00 Pa~eth 91-8 2.00 tc~ lO.O~
Wa~er ~t.
' - ' ::
- ~ D ~ 3 ~
A~ previou~ly de~cribed, pine oil i3 not e~estive again~t gram positive organi~m~, although it is effectiYe against gr~n ~egative organi~m~. It ha~
moreover only been po~ible to obtain di~inf ~¢tancy in 5a pine oil compositio~ against both gram negative and gram po3iti~re organi~ms in an acid me~ium. It iR, therefore, surprising that a combinatio~ of pine oil and a chelating agent,~ an oil soluble organics aci~,~
together with a hydrotrope ha~ broad spe¢trwn di~infectancy and is effe~cti~r0 against both gram negative and gram po3itiYs bacterial at a pH o:E 8 lto 20 we haYe :~o~md that this i~ a truly ~ynergi~tic effect since a composition oo~taining pine oil but no chelating agent was ine~fe~tive again~t taphylo¢oc~us aureu~ ~gram po~itive). ~ ~imilar compo~ition containing pine oil but no hydrothrope wa~ also i~æ~ f ecti.ve against ~ 0 aureu~ . A ~imil~r compo~ition with neither chelate ~or hydrotrope wa~ al80 inef~ective again~t SO aureus. Thu~ thi~ compositio~
ha~ broad ~peotrum disinfecta~cy ~i~ce it is ef~e¢tive agai~st both gram po~itive a~d gram ~egati~e organism~.
Ths pre~ent liquid hard ~urface cleaner thu3 has us~ in hospital~ " duR to it~ broad spsctrum a~tivity, in i~du~trial u~e and oo~sumer use. q!lle 2 5co~positio~ cordiIIg to the i:nvelltio~, give~
excellent clea~ing o~ grea~y, grimy, fiIlgerpri~lt 2md ~oap ~cum oil~. The combination of pille o;l, chelati~g agent arld hydrotrope i~ ~afe enc>ugh ~or u~e a~ a consumer produat.
I~ order to demon~trat2 the . ynergi~tic broad ~pes:trum di in~ec:tanoy e*~ect o~ the clea~er of ~he pre~ent in~rantio3l, the following ~pecific Example~ are set ~orth:
Example~ I to IV
~ ~ormulatio~ ~I) accordi~g to the pre~ent application was prepared with the ingredient ana amounts thereof a~ ~hown i~ T~ble I and havi~g a p~ of betwee~ ~ and 12.
For~ulation~ II, ]~II, IV and V were prepar2d identical to ~ormulation I, with ~he paramet~rs varied a3 ~hown i~ Table II, Exampl0 II
Formulation~ of I to V o~ Example I were subjected to microbiological te3ting according to the As~ociation of Official Analytical Chemi~t~ - U~e dilution Nethod (AOAC-~DM) proedure as used by the - 15 Environmental Prote~tion Agency (EPA~ and i~dust~y in ge~3ral, again~t S. aureus. The re~ult~ are ~ho~ i~
Table XI.
~; 20 .
;
,9 ~
a o rl o I ~ o a I ~ ~ ~ ~ ~ 0 E~ .rl O -I O
I p~ rl ~ h O-r ~ ~ ~ ~ ~ o ~ ~ a ~ ~; D~ O ~ O ~d O ~ a) o Z
o ~ .~
H ~ O .a ~ A P- :3 E-l ~ ~ U tq o ,~
l¢ t~ 'g ~ ~d :zs o ~ o o. o o o o a H C) :~ Z ~; Z Z Z t;- rl p:l :~: ~
O h nl D
,~ ~, ~! ,, r: E~ b~
H ~ t~ H Pl b 1~
~ 1~1 ~ ~'¢ ~ .0 5~`
~: :1:1 ~ ~1 o E~
W ~ ~0 O ~ O~ ~
, ~ 1~ E~ o o o o o 1 ~ I
IP; I
~n I E~ I o E l ¦ p ~ d ~1 3 O
~n .: 1~ o~
1~ h ~ ~
1 ~ I o~ I ~ ~
1 i3 I ~ I
IZ I ~ I a~ 0 ~ D~ O
~ -I I ~ 1 + I ~ ~ ~~ I
IP~ I :~ I :~ I :1 ~ U~
I tc ~ ~ I ~I ta E~ I El Id E~ rl-r~
1 ~ w IW P: . ~ I ~ h h ~ U P~
I ~ O tol ~ I ~ ~al ~ ~51 ~ col ~ ~ ~1 e ~0 ~
~q ~ ~
iE~ ~ O ~
U r~ ~
oq v ~ . Vo ~ O ~ ~r CO ~ ~ 0 ~ ~; ~ I I t~
H W I ~ u~ i~ I ~ X ~3 X tq ~ r4 rl rl ~1 ¦ N C~ N 0 N ON 4 N O
O ~1 1`~ 0 S` I~b oI~ C~ 1`
O ta N ~ ~ N ~N ~ N 0 S~ W
WD ~ . . . .
E~ C H H H P P
O liil 1-1 H 1-1 i5 0C H
xample III 2 ~
A number of Example~ o~ Formulation I of Example I were submitted to microbiological te~ting again~t staphylococcu3 aureu~* (~ynthetic nutrie~t), 5almonella choleraesuiq* ~ynthatic nutrient~, P~eudomona~ aeru~ino~a~ ~utrient) and E~cherichia coli* ~nutrient). The resul.ts are ~hown in Table III.
It will be ~een that these formulation~ have di~in~ectancy activity again~t both gram po~itive a~d gram negative organism~ and thu~ broad ~pectrum disinfectancy:
* ~. aureu~ ~ gram po~itiva 8. cholerae3ui~ - gram ~egatiYe P. aerugino~a - gram negativ~ -E. coli ~ gram ~egative 9 ~ 3 ~
TABLE III
8UMMARY OF MICROBIOLOGI~AL TESTING OF_~
PINE OI~ BAS~D DISINFECTING COMPOSITION
NOTEBOO~ &
~ICRO. REQUE8T PASS
NUMBERS ORGANI8~ RE8ULT* FAI~
I. 2742-54-31 S. aureu~ 60 /60 P
90-047 gram ~
II. 2709-122-1 S. aureus 60-~60 P
90-051 gram ~
III. 2709-122-~ S. aureu~ 60-/60 P
90-051 gram ~
IV. 27~2-131 g. choleraesuis 60-/60 P
90-134 qr~m -V. 2742-131 E. coli 20-/20 P
90-134 gram -VI. 2742-131 P~. aerugino~a 20-~20 P
90-13~ gram ~
* The disi~$ectancy test procedure~ wer~ co~ducted accordi~g to the Official ~ethod~ of Analysi~ o~ the A~ociation of OPficial ~nalytical Chemist~ th ~a.
1984~ Chapter ~ Di i~ecta~t~ P~rayraph~ 4.007-4~0~1 ~e Dilutio~ Nathod~
9 ~ $
-- ~o --The unexpected co~binatio~ oP small amount~
of a chelating agent su~h a ~etrasodium EDTA ~0.1%) and a hydrotrope ~uch a~ ~odiu~ xyl~ne sulfonate tl.5%) can broad~ the antimicrobial aatiYity of pine oil (2D%) in an emul~ified ~ystem. In the presenc~ of the aforementioned chemical specie~, pi~e oil can ~ot exhibit broad ~pectrum di~3i~fectant activity by achieving 100% ~ill of both gram positive ~. aureu~) and gra~ negative ba~teria ~S. cholerae~ui~ ~. coli, Ps. aerugino~a) as defined by the O~icial Method~ of ~alysis of the aoAc. ~ata in TABLE III veri~ies bro~d spectxum aotivity a~d TAB~E II establishea the - combinational effeat of chelant a~d hydrotrope to potentiate pine oil aetivity.
It will b9 see~ that the combination o~ pine oil and chelato with a hy~rotrope ha~ a clear and, qurprisingly, ~y~ergi~tic e~ect i~ providi~g ~ disi~f~cta~cy aotivity a~ai~st both gram po~itive and - gram negative organi~ms and that a liquid cleaner i~
provided for hard surface~ having a broad ~pectrum activity whioh i~ ~ot harsh to 3ki~, eye~ and ~ur~aoe~
.
Thi~ i,veIlltion r~31ate~ to an alkaline basQd ~urfa(:e cleaner having broa~ spectrUDI di~3in~ecta~ ia~d ao~tailling pi~ oilO
A ~umber of pin~ oil aontaining s~lealler3 ~re knowIl ~Eor cleani~g h~rd ~urf~Ge~, i.e. poroelain, enaDIel ~ plastic~ ate~ and tha li~e. æu~h clean~rs are ~ffeative ~or oleaning greasy soil, and in combinatioll with Gertai~ ~urfactant~3 th2y have been ei~Eective i~l cle~ni~g grimy ~oil from su:cfac:e.
however, pi~e oil b.sed oleaner3 hurQ ~ot be~ll found to ha~e broad spe¢trum anti~icrobial aotivity since they are o~ly effeotiYe again~t gra~ negative organi~m~ and ~ot against gram posiltive oxga~ism U~ 8 sauater~ary ammonium c:o~psunas are pr~ ent. Th~ use o~ quaternary ~o~polma~ in a oleaner i~ ~ot desirable 5illl:e the~e compound~ have a r~umber of unde~irable gualitie~, A
higll r~ lue is le~t o~ the surfaae after c:lea~i~gO I~
addiltiont quaternary ammo~ium co~npou~d are too tonic for this U~38 ~nd are highly irritati:llg to the skin, eye~, etc.
Ill IJnit d 8tate~ Patent ~umber 4,867,898, it is di~closed t~hat a broad spç30trum pine oil d:L~infec:ta~ay liquid cleaner, efiEeo1:ive against both gram positive and gram negativ0 orga~lism~, aould be ~ 2 ~ J~
obtained by a co~bination of pi~e oil and oil solllble organic aaids a~ a pH of O to 6. ~lthough this formulation ~as a~ efiE6!~tive, broad 8peCtrllm~
~isi~a~ecting c:leanzr, it ~uf~erad frs:m the di3advantage that it was hars~ to the satin~ eye5 and also to the surPaGes to be cleaner~ Tlhus, this clea~er wa~ not entireïy satisfactory ~or general ~leani~g U5e~o It i~ kno~n that alkaline ba~sed pine oil ~yYtem3 are ~ot so harsh. ~Iowever, it has not 1~ heretofore been pos~ible to obtain ~n alkallne based pine oil cleaner haviny broad spec:tsum di~in~ectallc:y against both gram positive and gr~ negative organism~.
8uch formulations were ef:Eeati~e only agai:nst gram negative ors~anism3.
It is there~ore a~ obj Qat o~ this invention to provide a pine oil con1:aini~g hard ~urface cleaner that has broad spectrum disinectancy, but is not harsh to skin, eyes and the surfa~es bei~g ~lea~ed.
A ~urther objeat is to o~tain a pi~e oil aontaini~g hard ~Ur~Ge ~leaner~ in an alkali~e medium having broad spectrum disi~feotanc~0 We ha~e now foun~ that pi~e oil becomes a true broad spectrum disi~fec~ant in the prese~ce of small amou~ts~ chelati~g agent and hydrotrope in a alkaline based e~ulsion produc The raw material in the amounts thereo~ are non-toxi~, non-irritating, ~o medici~al odor, compatible with pi~e oil i~ a properly emulsi~ied system~ co~Yenient and easy to use i~ a v riety o~ consumer and indu~trial hard surface disinfe~tant cleaning pro~u~ts~
Numerou~ household, nstitutional, industrial, and agricultuxal surfaces becom~
cont2minated with bo~h gram negative and gram posit v~
baateria. The presen~e o~ pine sil, tetraso~ium EDTA, and ~odi~m xylene sulfonate in an al~aline based .
cleaning preparation will totally diainfect that hard ~urface and deodorize the room without harm to human~
an~ animals.
The ingredient~ and amount~ that mak~ up tha haxd ~urface cleaner of the pre~ent inve~tion ars listed in Table I belo~. It will be under~tood that the listing of chelating agent~ and hydrotropes i~
e~emplary and not in¢lu~ive.
~ 9 ~
TABI.13 I
PINE: OIL DISINF}:C:TING COMPOæITION
WIT~ CON_E~TRA~rION RANGES
Pi~le Oil 10 . 00 to 30 . Ob Tetra~odium EDTA O . 01 to 5 . 00 Sodium Xyle~-e ~;ul~onate 1. 00 to 15 . 00 I~opropallol 3 . 00 to 10 . 00 Pareth-25 Sulfate 2 . 00 to 16 . 00 Sodiu~ C14-C16 Ole~in sul~onate 2 . 00 to 16 . 00 Li~3ar AlkylBe~ze~l~ æul~o~ate 2.00 to 16.00 Pa~eth 91-8 2.00 tc~ lO.O~
Wa~er ~t.
' - ' ::
- ~ D ~ 3 ~
A~ previou~ly de~cribed, pine oil i3 not e~estive again~t gram positive organi~m~, although it is effectiYe against gr~n ~egative organi~m~. It ha~
moreover only been po~ible to obtain di~inf ~¢tancy in 5a pine oil compositio~ against both gram negative and gram po3iti~re organi~ms in an acid me~ium. It iR, therefore, surprising that a combinatio~ of pine oil and a chelating agent,~ an oil soluble organics aci~,~
together with a hydrotrope ha~ broad spe¢trwn di~infectancy and is effe~cti~r0 against both gram negative and gram po3itiYs bacterial at a pH o:E 8 lto 20 we haYe :~o~md that this i~ a truly ~ynergi~tic effect since a composition oo~taining pine oil but no chelating agent was ine~fe~tive again~t taphylo¢oc~us aureu~ ~gram po~itive). ~ ~imilar compo~ition containing pine oil but no hydrothrope wa~ also i~æ~ f ecti.ve against ~ 0 aureu~ . A ~imil~r compo~ition with neither chelate ~or hydrotrope wa~ al80 inef~ective again~t SO aureus. Thu~ thi~ compositio~
ha~ broad ~peotrum disinfecta~cy ~i~ce it is ef~e¢tive agai~st both gram po~itive a~d gram ~egati~e organism~.
Ths pre~ent liquid hard ~urface cleaner thu3 has us~ in hospital~ " duR to it~ broad spsctrum a~tivity, in i~du~trial u~e and oo~sumer use. q!lle 2 5co~positio~ cordiIIg to the i:nvelltio~, give~
excellent clea~ing o~ grea~y, grimy, fiIlgerpri~lt 2md ~oap ~cum oil~. The combination of pille o;l, chelati~g agent arld hydrotrope i~ ~afe enc>ugh ~or u~e a~ a consumer produat.
I~ order to demon~trat2 the . ynergi~tic broad ~pes:trum di in~ec:tanoy e*~ect o~ the clea~er of ~he pre~ent in~rantio3l, the following ~pecific Example~ are set ~orth:
Example~ I to IV
~ ~ormulatio~ ~I) accordi~g to the pre~ent application was prepared with the ingredient ana amounts thereof a~ ~hown i~ T~ble I and havi~g a p~ of betwee~ ~ and 12.
For~ulation~ II, ]~II, IV and V were prepar2d identical to ~ormulation I, with ~he paramet~rs varied a3 ~hown i~ Table II, Exampl0 II
Formulation~ of I to V o~ Example I were subjected to microbiological te3ting according to the As~ociation of Official Analytical Chemi~t~ - U~e dilution Nethod (AOAC-~DM) proedure as used by the - 15 Environmental Prote~tion Agency (EPA~ and i~dust~y in ge~3ral, again~t S. aureus. The re~ult~ are ~ho~ i~
Table XI.
~; 20 .
;
,9 ~
a o rl o I ~ o a I ~ ~ ~ ~ ~ 0 E~ .rl O -I O
I p~ rl ~ h O-r ~ ~ ~ ~ ~ o ~ ~ a ~ ~; D~ O ~ O ~d O ~ a) o Z
o ~ .~
H ~ O .a ~ A P- :3 E-l ~ ~ U tq o ,~
l¢ t~ 'g ~ ~d :zs o ~ o o. o o o o a H C) :~ Z ~; Z Z Z t;- rl p:l :~: ~
O h nl D
,~ ~, ~! ,, r: E~ b~
H ~ t~ H Pl b 1~
~ 1~1 ~ ~'¢ ~ .0 5~`
~: :1:1 ~ ~1 o E~
W ~ ~0 O ~ O~ ~
, ~ 1~ E~ o o o o o 1 ~ I
IP; I
~n I E~ I o E l ¦ p ~ d ~1 3 O
~n .: 1~ o~
1~ h ~ ~
1 ~ I o~ I ~ ~
1 i3 I ~ I
IZ I ~ I a~ 0 ~ D~ O
~ -I I ~ 1 + I ~ ~ ~~ I
IP~ I :~ I :~ I :1 ~ U~
I tc ~ ~ I ~I ta E~ I El Id E~ rl-r~
1 ~ w IW P: . ~ I ~ h h ~ U P~
I ~ O tol ~ I ~ ~al ~ ~51 ~ col ~ ~ ~1 e ~0 ~
~q ~ ~
iE~ ~ O ~
U r~ ~
oq v ~ . Vo ~ O ~ ~r CO ~ ~ 0 ~ ~; ~ I I t~
H W I ~ u~ i~ I ~ X ~3 X tq ~ r4 rl rl ~1 ¦ N C~ N 0 N ON 4 N O
O ~1 1`~ 0 S` I~b oI~ C~ 1`
O ta N ~ ~ N ~N ~ N 0 S~ W
WD ~ . . . .
E~ C H H H P P
O liil 1-1 H 1-1 i5 0C H
xample III 2 ~
A number of Example~ o~ Formulation I of Example I were submitted to microbiological te~ting again~t staphylococcu3 aureu~* (~ynthetic nutrie~t), 5almonella choleraesuiq* ~ynthatic nutrient~, P~eudomona~ aeru~ino~a~ ~utrient) and E~cherichia coli* ~nutrient). The resul.ts are ~hown in Table III.
It will be ~een that these formulation~ have di~in~ectancy activity again~t both gram po~itive a~d gram negative organism~ and thu~ broad ~pectrum disinfectancy:
* ~. aureu~ ~ gram po~itiva 8. cholerae3ui~ - gram ~egatiYe P. aerugino~a - gram negativ~ -E. coli ~ gram ~egative 9 ~ 3 ~
TABLE III
8UMMARY OF MICROBIOLOGI~AL TESTING OF_~
PINE OI~ BAS~D DISINFECTING COMPOSITION
NOTEBOO~ &
~ICRO. REQUE8T PASS
NUMBERS ORGANI8~ RE8ULT* FAI~
I. 2742-54-31 S. aureu~ 60 /60 P
90-047 gram ~
II. 2709-122-1 S. aureus 60-~60 P
90-051 gram ~
III. 2709-122-~ S. aureu~ 60-/60 P
90-051 gram ~
IV. 27~2-131 g. choleraesuis 60-/60 P
90-134 qr~m -V. 2742-131 E. coli 20-/20 P
90-134 gram -VI. 2742-131 P~. aerugino~a 20-~20 P
90-13~ gram ~
* The disi~$ectancy test procedure~ wer~ co~ducted accordi~g to the Official ~ethod~ of Analysi~ o~ the A~ociation of OPficial ~nalytical Chemist~ th ~a.
1984~ Chapter ~ Di i~ecta~t~ P~rayraph~ 4.007-4~0~1 ~e Dilutio~ Nathod~
9 ~ $
-- ~o --The unexpected co~binatio~ oP small amount~
of a chelating agent su~h a ~etrasodium EDTA ~0.1%) and a hydrotrope ~uch a~ ~odiu~ xyl~ne sulfonate tl.5%) can broad~ the antimicrobial aatiYity of pine oil (2D%) in an emul~ified ~ystem. In the presenc~ of the aforementioned chemical specie~, pi~e oil can ~ot exhibit broad ~pectrum di~3i~fectant activity by achieving 100% ~ill of both gram positive ~. aureu~) and gra~ negative ba~teria ~S. cholerae~ui~ ~. coli, Ps. aerugino~a) as defined by the O~icial Method~ of ~alysis of the aoAc. ~ata in TABLE III veri~ies bro~d spectxum aotivity a~d TAB~E II establishea the - combinational effeat of chelant a~d hydrotrope to potentiate pine oil aetivity.
It will b9 see~ that the combination o~ pine oil and chelato with a hy~rotrope ha~ a clear and, qurprisingly, ~y~ergi~tic e~ect i~ providi~g ~ disi~f~cta~cy aotivity a~ai~st both gram po~itive and - gram negative organi~ms and that a liquid cleaner i~
provided for hard surface~ having a broad ~pectrum activity whioh i~ ~ot harsh to 3ki~, eye~ and ~ur~aoe~
.
Claims (9)
1. A liquid cleaner for hard surfaces having broad spectrum disinfectancy activity comprising pine oil and at least one chelating agent and one hydrotrope.
2. The cleaner of Claim 1 wherein the composition has a pH of 8 to 12.
3. The cleaner of. Claim 1 wherein said chelating agent is tetrasodium ethylene diamene tetra acetic acid.
4. The cleaner of claim 1 wherein said hydrotrope is sodium xylene sulfonate.
5. The cleaner of Claim 1 which contains in addition organic detergent compounds.
6. The cleaner of claim 1 containing in addition isopropyl alcohol.
7. The cleaner of Claim 1 containing in addition fenchyl alcohol.
8. The cleaner of Claim 1 containing in addition ammonium hydroxide.
9. A method of imparting broad spectrum disinfectant activity to a surface comprising applying to said surface a liquid cleaner composition, said composition pine oil, and at least one chelating agent, and at least one hydrotrope, at a pH of 8 to 12.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55272990A | 1990-07-16 | 1990-07-16 | |
| US07/552,729 | 1990-07-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2046996A1 true CA2046996A1 (en) | 1992-01-17 |
Family
ID=24206560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002046996A Abandoned CA2046996A1 (en) | 1990-07-16 | 1991-07-12 | Broad spectrum antimicrobial system for hard surface cleaners |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0467618A1 (en) |
| JP (1) | JPH04261500A (en) |
| KR (1) | KR920002762A (en) |
| AU (1) | AU8048991A (en) |
| BR (1) | BR9103010A (en) |
| CA (1) | CA2046996A1 (en) |
| MX (1) | MX9100239A (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9408940D0 (en) * | 1994-05-05 | 1994-06-22 | Procter & Gamble | Manual dishwashing compositions |
| FR2727290B1 (en) * | 1994-11-30 | 1999-04-02 | Derives Resiniques Terpenique | USE OF A COMBINATION OF TERPENIC ALCOHOL AND NON-BACTERICIDAL SURFACTANT AS A BACTERICIDAL MIXTURE AND COMPOSITION THEREOF |
| US5866534A (en) * | 1995-06-12 | 1999-02-02 | Colgate-Palmolive Co. | Stable liquid cleaners containing pine oil |
| DE69635690T2 (en) * | 1995-06-27 | 2006-09-14 | The Procter & Gamble Company, Cincinnati | Methods, compositions and articles for cleaning and sterilizing non-food lifeless surfaces |
| SK94598A3 (en) * | 1996-01-12 | 1999-04-13 | Procter & Gamble | Disinfecting compositions and processes for disinfecting surfaces |
| CA2218256C (en) | 1996-02-14 | 2006-05-30 | Stepan Company | Reduced residue hard surface cleaner comprising hydrotrope |
| CN1071998C (en) * | 1996-07-16 | 2001-10-03 | 普罗格特-甘布尔公司 | Use of combination of surfactants, chelating agents and essential oils for effective disinfection |
| US6048836A (en) * | 1996-07-16 | 2000-04-11 | The Procter & Gamble Company | Use of a combination of surfactants, chelating agents and essential oils for effective disinfection |
| KR20000023826A (en) * | 1999-01-16 | 2000-04-25 | 데이비드 엠 모이어 | Use of a combination of surfactants, chelating agents and essential oils for effective disinfection |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1237874A (en) * | 1967-07-19 | 1971-06-30 | Unilever Australia Proprietary | Detergent composition |
| US3634338A (en) * | 1970-07-10 | 1972-01-11 | Grace W R & Co | Method and composition for cleaning aluminum magnesiumand alloys thereof |
| US3703472A (en) * | 1970-07-29 | 1972-11-21 | West Laboratories Inc | Pine-ammonia detergent composition |
| US3915880A (en) * | 1973-03-23 | 1975-10-28 | Gilberto Sepulveda | Pine oil-ammonia cleansing composition |
| CA1153267A (en) * | 1981-02-17 | 1983-09-06 | American Cyanamid Company | Disinfectant cleaner composition |
| ATE34405T1 (en) * | 1984-01-06 | 1988-06-15 | Procter & Gamble | FLEXIBLE CONTAINERS TO CONTAIN A LIQUID PRODUCT AND PREVENTION OF VACUUM COLLAPSE IN THE CONTAINERS. |
| US4589994A (en) * | 1984-12-17 | 1986-05-20 | Moseman Roger E | Liquid foot treatment composition |
| US4867898A (en) * | 1987-03-23 | 1989-09-19 | American Cyanamid Company | Broad spectrum antimicrobial system for hard surface cleaners |
-
1991
- 1991-07-12 CA CA002046996A patent/CA2046996A1/en not_active Abandoned
- 1991-07-15 EP EP91306383A patent/EP0467618A1/en not_active Withdrawn
- 1991-07-15 BR BR919103010A patent/BR9103010A/en not_active Application Discontinuation
- 1991-07-16 AU AU80489/91A patent/AU8048991A/en not_active Abandoned
- 1991-07-16 JP JP3199803A patent/JPH04261500A/en active Pending
- 1991-07-16 KR KR1019910012153A patent/KR920002762A/en not_active Application Discontinuation
- 1991-07-16 MX MX9100239A patent/MX9100239A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0467618A1 (en) | 1992-01-22 |
| BR9103010A (en) | 1992-04-28 |
| KR920002762A (en) | 1992-02-28 |
| MX9100239A (en) | 1992-02-28 |
| JPH04261500A (en) | 1992-09-17 |
| AU8048991A (en) | 1992-01-16 |
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