CA2038828A1 - Derives 2-(pyrrolidinyle substitue) de carbapenemes - Google Patents
Derives 2-(pyrrolidinyle substitue) de carbapenemesInfo
- Publication number
- CA2038828A1 CA2038828A1 CA2038828A CA2038828A CA2038828A1 CA 2038828 A1 CA2038828 A1 CA 2038828A1 CA 2038828 A CA2038828 A CA 2038828A CA 2038828 A CA2038828 A CA 2038828A CA 2038828 A1 CA2038828 A1 CA 2038828A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- con
- lower alkyl
- hydrogen atom
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7743190 | 1990-03-27 | ||
JP77431/1990 | 1990-03-27 | ||
JP96654/1990 | 1990-04-12 | ||
JP9665490 | 1990-04-12 | ||
JP41463790 | 1990-12-27 | ||
JP414637/1990 | 1990-12-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2038828A1 true CA2038828A1 (fr) | 1991-09-28 |
CA2038828C CA2038828C (fr) | 1996-09-24 |
Family
ID=27302418
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002038828A Expired - Fee Related CA2038828C (fr) | 1990-03-27 | 1991-03-22 | Derives 2-(pyrrolidinyle substitue) de carbapenemes |
Country Status (17)
Country | Link |
---|---|
US (1) | US5438054A (fr) |
EP (1) | EP0449191B1 (fr) |
KR (1) | KR0175946B1 (fr) |
AT (1) | ATE140005T1 (fr) |
AU (1) | AU635118B2 (fr) |
CA (1) | CA2038828C (fr) |
CS (1) | CS83991A2 (fr) |
DE (1) | DE69120572T2 (fr) |
FI (1) | FI915026A0 (fr) |
HU (2) | HUT60498A (fr) |
IE (1) | IE910978A1 (fr) |
IL (1) | IL97685A (fr) |
NZ (1) | NZ237558A (fr) |
PT (1) | PT97152A (fr) |
TW (1) | TW198034B (fr) |
WO (1) | WO1991014687A1 (fr) |
YU (1) | YU54891A (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU631671B2 (en) * | 1989-08-04 | 1992-12-03 | Banyu Pharmaceutical Co., Ltd. | 2-(2-vinylpyrrolidinylthio)carbapenem derivatives |
JP2559949B2 (ja) * | 1991-06-04 | 1996-12-04 | 三共株式会社 | 1−メチルカルバペネム誘導体 |
JP3848693B2 (ja) * | 1994-07-06 | 2006-11-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 新規カルバペネム誘導体 |
US5475138A (en) * | 1994-07-07 | 1995-12-12 | Pharm-Eco Laboratories Incorporated | Method preparing amino acid-derived diaminopropanols |
ATE201197T1 (de) * | 1994-07-07 | 2001-06-15 | Pharmeco Lab Inc | Diarinopropanole abgeleitet von aminosäuren |
EP0722945A1 (fr) | 1995-01-18 | 1996-07-24 | Zeneca Limited | Dérivés d'acide 9-oxo-1-azabicyclo-(5.2.0)non-2,4-diène-2-carboxylique, en tant qu'antibiotiques |
US6063963A (en) * | 1995-07-05 | 2000-05-16 | Pharm-Eco Laboratories, Inc. | Amino acid-derived diaminopropanols |
NZ324447A (en) * | 1995-12-21 | 1999-08-30 | Sankyo Co | 1-methyl-carbapenem substituted by a 4-pyrrolidinylthio group and medicaments |
US7932381B2 (en) * | 2005-02-15 | 2011-04-26 | Shionogi & Co., Ltd. | Process for producing carbapenem derivative and intermediate crystal therefor |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1283906C (fr) * | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | COMPOSE DE .beta.-LACTAM ET PROCEDE DE PRODUCTION |
DE3784147T2 (de) * | 1986-11-24 | 1993-06-03 | Fujisawa Pharmaceutical Co | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)hept-2-en-2-carbonsaeure-derivate. |
KR880006244A (ko) * | 1986-11-24 | 1988-07-22 | 후지사와 도모 기찌 로 | 3-피롤리디닐티오-1-아자바이스클로[3.2.0]햅트2-엔-2-카르복실산 화합물 및 이의 제조방법 |
US4925838A (en) * | 1988-03-18 | 1990-05-15 | Fujisawa Pharmaceutical Company, Ltd. | 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds |
-
1991
- 1991-03-04 TW TW080101711A patent/TW198034B/zh active
- 1991-03-22 CA CA002038828A patent/CA2038828C/fr not_active Expired - Fee Related
- 1991-03-25 AU AU73725/91A patent/AU635118B2/en not_active Ceased
- 1991-03-25 IE IE097891A patent/IE910978A1/en not_active Application Discontinuation
- 1991-03-25 NZ NZ237558A patent/NZ237558A/xx unknown
- 1991-03-26 PT PT199197152A patent/PT97152A/pt not_active Application Discontinuation
- 1991-03-26 DE DE69120572T patent/DE69120572T2/de not_active Expired - Fee Related
- 1991-03-26 AT AT91104735T patent/ATE140005T1/de not_active IP Right Cessation
- 1991-03-26 EP EP91104735A patent/EP0449191B1/fr not_active Expired - Lifetime
- 1991-03-26 IL IL9768591A patent/IL97685A/en not_active IP Right Cessation
- 1991-03-27 KR KR1019910004826A patent/KR0175946B1/ko not_active IP Right Cessation
- 1991-03-27 HU HU913685A patent/HUT60498A/hu unknown
- 1991-03-27 YU YU54891A patent/YU54891A/sh unknown
- 1991-03-27 WO PCT/JP1991/000394 patent/WO1991014687A1/fr active Application Filing
- 1991-03-27 CS CS91839A patent/CS83991A2/cs unknown
- 1991-10-24 FI FI915026A patent/FI915026A0/fi not_active Application Discontinuation
-
1994
- 1994-03-09 US US08/208,046 patent/US5438054A/en not_active Expired - Lifetime
-
1995
- 1995-02-17 HU HU95P/P00081P patent/HU210823A9/hu unknown
Also Published As
Publication number | Publication date |
---|---|
HU210823A9 (en) | 1995-08-28 |
HU913685D0 (en) | 1992-07-28 |
KR0175946B1 (ko) | 1999-03-20 |
CS83991A2 (en) | 1991-11-12 |
ATE140005T1 (de) | 1996-07-15 |
IE910978A1 (en) | 1991-10-09 |
KR910016755A (ko) | 1991-11-05 |
DE69120572T2 (de) | 1997-01-09 |
IL97685A0 (en) | 1992-06-21 |
DE69120572D1 (de) | 1996-08-08 |
FI915026A0 (fi) | 1991-10-24 |
CA2038828C (fr) | 1996-09-24 |
AU7372591A (en) | 1992-01-23 |
WO1991014687A1 (fr) | 1991-10-03 |
US5438054A (en) | 1995-08-01 |
PT97152A (pt) | 1991-11-29 |
YU54891A (sh) | 1994-01-20 |
AU635118B2 (en) | 1993-03-11 |
IL97685A (en) | 1995-11-27 |
TW198034B (fr) | 1993-01-11 |
EP0449191B1 (fr) | 1996-07-03 |
EP0449191A1 (fr) | 1991-10-02 |
NZ237558A (en) | 1993-04-28 |
HUT60498A (en) | 1992-09-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |