CA2008817A1 - Anticorps monoclonaux m-csf reconnaissant un epitope conformationnel neutralisant - Google Patents

Anticorps monoclonaux m-csf reconnaissant un epitope conformationnel neutralisant

Info

Publication number
CA2008817A1
CA2008817A1 CA2008817A CA2008817A CA2008817A1 CA 2008817 A1 CA2008817 A1 CA 2008817A1 CA 2008817 A CA2008817 A CA 2008817A CA 2008817 A CA2008817 A CA 2008817A CA 2008817 A1 CA2008817 A1 CA 2008817A1
Authority
CA
Canada
Prior art keywords
monoclonal antibodies
conformational epitope
recognize
csf
csf monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2008817A
Other languages
English (en)
Other versions
CA2008817C (fr
Inventor
Robert F. Halenbeck
Kirston E. Koths
Joseph W. Wrin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2008817A1 publication Critical patent/CA2008817A1/fr
Application granted granted Critical
Publication of CA2008817C publication Critical patent/CA2008817C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002008817A 1989-02-10 1990-01-29 Anticorps monoclonaux m-csf reconnaissant un epitope conformationnel neutralisant Expired - Lifetime CA2008817C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31004289A 1989-02-10 1989-02-10
US310,042 1989-02-10

Publications (2)

Publication Number Publication Date
CA2008817A1 true CA2008817A1 (fr) 1990-08-10
CA2008817C CA2008817C (fr) 2000-03-14

Family

ID=23200753

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002008817A Expired - Lifetime CA2008817C (fr) 1989-02-10 1990-01-29 Anticorps monoclonaux m-csf reconnaissant un epitope conformationnel neutralisant

Country Status (9)

Country Link
US (1) US5491065A (fr)
EP (1) EP0457804B1 (fr)
JP (1) JP3001969B2 (fr)
AT (1) ATE141290T1 (fr)
CA (1) CA2008817C (fr)
DE (1) DE69028095T2 (fr)
DK (1) DK0457804T3 (fr)
ES (1) ES2091816T3 (fr)
WO (1) WO1990009400A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096540A (en) * 1996-09-30 2000-08-01 Becton Dickinson And Company Differentiation of granulocytic and monocytic progenitor cells
US6363129B1 (en) 1998-11-09 2002-03-26 Broadcom Corporation Timing recovery system for a multi-pair gigabit transceiver
AU1759501A (en) * 1999-11-08 2001-06-06 Government of The United States of America, as represented by The Secretary Department of Health & Human Services, The National Institutes of Health, The Method of treating a viral infection using antagonists of macrophage colony stimulating factor
US7108852B2 (en) * 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
US20110091451A1 (en) * 2002-11-15 2011-04-21 Kavanaugh William M Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
DE60332483D1 (de) * 2002-11-15 2010-06-17 Novartis Vaccines & Diagnostic Methoden zur verhinderung und behandlung von krebs-metastasierung und mit krebs-metastasierung einhergehendem knochenverlust
AR045563A1 (es) * 2003-09-10 2005-11-02 Warner Lambert Co Anticuerpos dirigidos a m-csf
RU2401277C2 (ru) 2004-01-07 2010-10-10 Чирон Корпорейшн Не мышиное анти-m-csf-антитело (варианты), его получение и использование
AU2005255019B2 (en) * 2004-06-12 2011-05-19 Oregon Health And Science University Compositions and methods for diagnosis and treatment of orthopoxviruses
CA2600601A1 (fr) * 2005-03-08 2006-09-14 Pharmacia & Upjohn Company Llc Compositions d'anticorps anti-m-csf a niveaux d'endotoxine reduits
EP2311876A3 (fr) * 2005-07-28 2011-04-27 Novartis AG Anticorps monoclonal spécifique du M-CSF et ses utilisations
US20080233118A1 (en) * 2005-07-28 2008-09-25 Novartis Ag Uses Of Antibody To M-Csf
EP2705854A1 (fr) 2006-01-05 2014-03-12 Novartis AG Procédés de prévention et de traitement des métastases de cancer et perte osseuse associée aux métastases de cancer
WO2013011021A1 (fr) 2011-07-18 2013-01-24 The University Of Melbourne Utilisation d'antagonistes de c-fms
SG11201507871XA (en) 2013-04-12 2015-10-29 Morphosys Ag Antibodies targeting m-csf

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4504586A (en) * 1983-02-03 1985-03-12 Amgen Hybridoma tumor cell lines and their monoclonal antibodies to human colony stimulating factor subclass number 1
AU588819B2 (en) * 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene
ATE92966T1 (de) * 1986-05-06 1993-08-15 Genetics Inst Herstellung von m-csf.
GB8624899D0 (en) * 1986-10-17 1986-11-19 Sandoz Ltd Monoclonal antibodies
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1

Also Published As

Publication number Publication date
ATE141290T1 (de) 1996-08-15
EP0457804A1 (fr) 1991-11-27
EP0457804B1 (fr) 1996-08-14
DE69028095T2 (de) 1997-02-06
CA2008817C (fr) 2000-03-14
JP3001969B2 (ja) 2000-01-24
DK0457804T3 (da) 1996-09-23
JPH04503155A (ja) 1992-06-11
ES2091816T3 (es) 1996-11-16
US5491065A (en) 1996-02-13
WO1990009400A1 (fr) 1990-08-23
DE69028095D1 (de) 1996-09-19

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Legal Events

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