ATE141290T1 - M-csf-monoklonale antikörper, die ein neutralisierendes konformationales epitop erkennen - Google Patents

M-csf-monoklonale antikörper, die ein neutralisierendes konformationales epitop erkennen

Info

Publication number
ATE141290T1
ATE141290T1 AT90902943T AT90902943T ATE141290T1 AT E141290 T1 ATE141290 T1 AT E141290T1 AT 90902943 T AT90902943 T AT 90902943T AT 90902943 T AT90902943 T AT 90902943T AT E141290 T1 ATE141290 T1 AT E141290T1
Authority
AT
Austria
Prior art keywords
monoclonal antibodies
csf
conformational epitope
recognize
csf monoclonal
Prior art date
Application number
AT90902943T
Other languages
English (en)
Inventor
Robert F Halenbeck
Kirston E Koths
Joseph W Wrin
Original Assignee
Cetus Oncology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Oncology Corp filed Critical Cetus Oncology Corp
Application granted granted Critical
Publication of ATE141290T1 publication Critical patent/ATE141290T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT90902943T 1989-02-10 1990-01-17 M-csf-monoklonale antikörper, die ein neutralisierendes konformationales epitop erkennen ATE141290T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31004289A 1989-02-10 1989-02-10

Publications (1)

Publication Number Publication Date
ATE141290T1 true ATE141290T1 (de) 1996-08-15

Family

ID=23200753

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90902943T ATE141290T1 (de) 1989-02-10 1990-01-17 M-csf-monoklonale antikörper, die ein neutralisierendes konformationales epitop erkennen

Country Status (9)

Country Link
US (1) US5491065A (de)
EP (1) EP0457804B1 (de)
JP (1) JP3001969B2 (de)
AT (1) ATE141290T1 (de)
CA (1) CA2008817C (de)
DE (1) DE69028095T2 (de)
DK (1) DK0457804T3 (de)
ES (1) ES2091816T3 (de)
WO (1) WO1990009400A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096540A (en) * 1996-09-30 2000-08-01 Becton Dickinson And Company Differentiation of granulocytic and monocytic progenitor cells
US6363129B1 (en) 1998-11-09 2002-03-26 Broadcom Corporation Timing recovery system for a multi-pair gigabit transceiver
AU1759501A (en) * 1999-11-08 2001-06-06 Government of The United States of America, as represented by The Secretary Department of Health & Human Services, The National Institutes of Health, The Method of treating a viral infection using antagonists of macrophage colony stimulating factor
US7108852B2 (en) 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
CN1787837A (zh) 2002-11-15 2006-06-14 希龙公司 防止和治疗癌转移以及与癌转移相关的骨质损失的方法
US20110091451A1 (en) * 2002-11-15 2011-04-21 Kavanaugh William M Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
AR045563A1 (es) * 2003-09-10 2005-11-02 Warner Lambert Co Anticuerpos dirigidos a m-csf
HUE026132T2 (en) * 2004-01-07 2016-05-30 Novartis Vaccines & Diagnostics Inc M-CSF-specific monoclonal antibody and its uses
WO2005123966A2 (en) * 2004-06-12 2005-12-29 Oregon Health And Science University Compositions and methods for diagnosis and treatment of orthopoxviruses
EP1858928A2 (de) * 2005-03-08 2007-11-28 Pharmacia & Upjohn Company LLC Anti-m-csf-antikörperzusammensetzungen mit verringerten endotoxinniveaus
ES2538036T3 (es) * 2005-07-28 2015-06-16 Novartis Ag Uso de anticuerpo a M-CSF
JP5457671B2 (ja) * 2005-07-28 2014-04-02 ノバルティス アーゲー Ｍ−ｃｓｆ特異的モノクローナル抗体およびその使用
US20090246208A1 (en) * 2006-01-05 2009-10-01 Novartis Ag Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
EP2734547B1 (de) 2011-07-18 2016-12-21 The University of Melbourne Verwendung von c-fms-antagonisten
EA031471B1 (ru) 2013-04-12 2019-01-31 МорфоСис АГ Антитела, направленные на m-csf

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4504586A (en) * 1983-02-03 1985-03-12 Amgen Hybridoma tumor cell lines and their monoclonal antibodies to human colony stimulating factor subclass number 1
AU588819B2 (en) * 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene
MX9203130A (es) * 1986-05-06 1992-07-01 Genetics Inst Produccion de m-csf
GB8624899D0 (en) * 1986-10-17 1986-11-19 Sandoz Ltd Monoclonal antibodies
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1

Also Published As

Publication number Publication date
DE69028095D1 (de) 1996-09-19
JPH04503155A (ja) 1992-06-11
WO1990009400A1 (en) 1990-08-23
US5491065A (en) 1996-02-13
DK0457804T3 (da) 1996-09-23
ES2091816T3 (es) 1996-11-16
EP0457804A1 (de) 1991-11-27
CA2008817C (en) 2000-03-14
EP0457804B1 (de) 1996-08-14
CA2008817A1 (en) 1990-08-10
JP3001969B2 (ja) 2000-01-24
DE69028095T2 (de) 1997-02-06

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee