CA2006977A1 - Pharmaceutical compositions - Google Patents
Pharmaceutical compositionsInfo
- Publication number
- CA2006977A1 CA2006977A1 CA 2006977 CA2006977A CA2006977A1 CA 2006977 A1 CA2006977 A1 CA 2006977A1 CA 2006977 CA2006977 CA 2006977 CA 2006977 A CA2006977 A CA 2006977A CA 2006977 A1 CA2006977 A1 CA 2006977A1
- Authority
- CA
- Canada
- Prior art keywords
- suppository
- mould
- phase
- attachment
- flexible
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract description 4
- 239000000829 suppository Substances 0.000 claims abstract description 49
- 239000008384 inner phase Substances 0.000 claims abstract description 28
- 239000008385 outer phase Substances 0.000 claims abstract description 18
- 239000002511 suppository base Substances 0.000 claims abstract description 17
- 238000002844 melting Methods 0.000 claims abstract description 12
- 230000008018 melting Effects 0.000 claims abstract description 12
- 238000004519 manufacturing process Methods 0.000 claims abstract description 5
- 239000002775 capsule Substances 0.000 claims description 27
- 229920002545 silicone oil Polymers 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 4
- 238000003780 insertion Methods 0.000 claims description 3
- 230000037431 insertion Effects 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 2
- 239000004744 fabric Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 239000000463 material Substances 0.000 description 10
- 239000003814 drug Substances 0.000 description 7
- 230000005526 G1 to G0 transition Effects 0.000 description 5
- 239000013543 active substance Substances 0.000 description 5
- 238000009792 diffusion process Methods 0.000 description 4
- 239000007903 gelatin capsule Substances 0.000 description 3
- 108010010803 Gelatin Proteins 0.000 description 2
- BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 208000014617 hemorrhoid Diseases 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 239000000155 melt Substances 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 206010002153 Anal fissure Diseases 0.000 description 1
- 208000016583 Anus disease Diseases 0.000 description 1
- 208000009531 Fissure in Ano Diseases 0.000 description 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 1
- 208000015815 Rectal disease Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 229960005274 benzocaine Drugs 0.000 description 1
- 229960000199 bismuth subgallate Drugs 0.000 description 1
- JAONZGLTYYUPCT-UHFFFAOYSA-K bismuth subgallate Chemical compound OC(=O)C1=CC(O)=C2O[Bi](O)OC2=C1 JAONZGLTYYUPCT-UHFFFAOYSA-K 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- ALEXXDVDDISNDU-JZYPGELDSA-N cortisol 21-acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O ALEXXDVDDISNDU-JZYPGELDSA-N 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000003736 gastrointestinal content Anatomy 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 229960001067 hydrocortisone acetate Drugs 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 229960004194 lidocaine Drugs 0.000 description 1
- 229960005015 local anesthetics Drugs 0.000 description 1
- 229920002529 medical grade silicone Polymers 0.000 description 1
- 239000003094 microcapsule Substances 0.000 description 1
- 239000012768 molten material Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- -1 polydimethylsiloxane Polymers 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888830406A GB8830406D0 (en) | 1988-12-30 | 1988-12-30 | Pharmaceutical compositions |
| GB8830406.8 | 1988-12-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2006977A1 true CA2006977A1 (en) | 1990-06-30 |
Family
ID=10649281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2006977 Abandoned CA2006977A1 (en) | 1988-12-30 | 1990-01-02 | Pharmaceutical compositions |
Country Status (5)
| Country | Link |
|---|---|
| AU (1) | AU4819490A (enrdf_load_stackoverflow) |
| CA (1) | CA2006977A1 (enrdf_load_stackoverflow) |
| DE (1) | DE3991549T (enrdf_load_stackoverflow) |
| GB (1) | GB8830406D0 (enrdf_load_stackoverflow) |
| ZA (1) | ZA9017B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8830407D0 (en) * | 1988-12-30 | 1989-03-01 | Embil Koral | Pharmaceutical formulations |
-
1988
- 1988-12-30 GB GB888830406A patent/GB8830406D0/en active Pending
-
1989
- 1989-12-29 DE DE19893991549 patent/DE3991549T/de not_active Withdrawn
- 1989-12-29 AU AU48194/90A patent/AU4819490A/en not_active Abandoned
-
1990
- 1990-01-02 ZA ZA9017A patent/ZA9017B/xx unknown
- 1990-01-02 CA CA 2006977 patent/CA2006977A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ZA9017B (en) | 1991-05-29 |
| AU4819490A (en) | 1990-08-01 |
| GB8830406D0 (en) | 1989-03-01 |
| DE3991549T (enrdf_load_stackoverflow) | 1991-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |