CA1337407C - Dimeric peptides having a stimulatory effect on haemopoiesis and a process for their preparation - Google Patents

Dimeric peptides having a stimulatory effect on haemopoiesis and a process for their preparation

Info

Publication number
CA1337407C
CA1337407C CA000551089A CA551089A CA1337407C CA 1337407 C CA1337407 C CA 1337407C CA 000551089 A CA000551089 A CA 000551089A CA 551089 A CA551089 A CA 551089A CA 1337407 C CA1337407 C CA 1337407C
Authority
CA
Canada
Prior art keywords
cys
asp
lys
glu
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000551089A
Other languages
English (en)
French (fr)
Inventor
Ole Didrik Laerum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Nycomed AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed AS filed Critical Nycomed AS
Application granted granted Critical
Publication of CA1337407C publication Critical patent/CA1337407C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1024Tetrapeptides with the first amino acid being heterocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C07K7/067Hemoregulatory peptides based on sequence Glp-Glu-Asp-Cys-Lys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA000551089A 1986-11-06 1987-11-05 Dimeric peptides having a stimulatory effect on haemopoiesis and a process for their preparation Expired - Fee Related CA1337407C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868626539A GB8626539D0 (en) 1986-11-06 1986-11-06 Peptide compounds
GB8626539 1986-11-06

Publications (1)

Publication Number Publication Date
CA1337407C true CA1337407C (en) 1995-10-24

Family

ID=10606897

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000551089A Expired - Fee Related CA1337407C (en) 1986-11-06 1987-11-05 Dimeric peptides having a stimulatory effect on haemopoiesis and a process for their preparation

Country Status (15)

Country Link
US (1) US4987122A (US06319959-20011120-C00007.png)
EP (2) EP0330667A1 (US06319959-20011120-C00007.png)
JP (1) JP2599947B2 (US06319959-20011120-C00007.png)
AT (1) ATE77628T1 (US06319959-20011120-C00007.png)
AU (1) AU604279B2 (US06319959-20011120-C00007.png)
CA (1) CA1337407C (US06319959-20011120-C00007.png)
DE (1) DE3780000T2 (US06319959-20011120-C00007.png)
ES (1) ES2038675T3 (US06319959-20011120-C00007.png)
FI (1) FI92209C (US06319959-20011120-C00007.png)
GB (1) GB8626539D0 (US06319959-20011120-C00007.png)
GR (1) GR3005557T3 (US06319959-20011120-C00007.png)
IE (1) IE59342B1 (US06319959-20011120-C00007.png)
NZ (1) NZ222466A (US06319959-20011120-C00007.png)
WO (1) WO1988003535A1 (US06319959-20011120-C00007.png)
ZA (1) ZA878349B (US06319959-20011120-C00007.png)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO884054D0 (no) * 1988-09-13 1988-09-13 Bio Tech As Nytt pentapeptid og fremgangsmaate for fremstilling derav.
GB8821785D0 (en) * 1988-09-16 1988-10-19 Nycomed As Peptide compounds
ZW11290A1 (en) * 1989-07-14 1990-10-31 Smithkline Beecham Corp Hemoregulatory peptides
HU206372B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing new oligopeptides which selectively inhibit proliferation of haemopoietic cells and pharmaceutical compositions comprising same
DK53191D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Organosvovlforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
IL104323A0 (en) * 1992-01-10 1993-05-13 Smithkline Beecham Corp Hemoregulatory peptides
GB9211677D0 (en) 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
AU4340393A (en) * 1992-06-02 1993-12-30 Hafslund Nycomed As Double chain peptide compounds having hemoregulatory activity
GB9211668D0 (en) 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GB9211674D0 (en) 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
US6764693B1 (en) 1992-12-11 2004-07-20 Amaox, Ltd. Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants
ES2210255T3 (es) * 1993-06-08 2004-07-01 Smithkline Beecham Corporation Metodos para mejorar la actividad biologica de quimiocinas.
GB9314200D0 (en) * 1993-07-09 1993-08-18 Hafslund Nycomed As Peptide compounds
DE69420044T2 (de) * 1993-10-29 2000-03-23 Smithkline Beecham Corp Blutregulierende peptide
GB9324691D0 (en) * 1993-12-01 1994-01-19 Hafslund Nycomed As Peptide compounds
EP1021443A4 (en) * 1995-11-13 2001-02-07 Smithkline Beecham Corp HAMOREGULATIONAL CONNECTIONS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA838780B (en) * 1982-11-26 1985-01-30 Nyegaard & Co As Peptide compounds

Also Published As

Publication number Publication date
DE3780000T2 (de) 1993-02-04
US4987122A (en) 1991-01-22
EP0267741A1 (en) 1988-05-18
FI892185A (fi) 1989-05-05
AU8174787A (en) 1988-06-01
GR3005557T3 (US06319959-20011120-C00007.png) 1993-06-07
NZ222466A (en) 1990-09-26
EP0330667A1 (en) 1989-09-06
AU604279B2 (en) 1990-12-13
FI92209B (fi) 1994-06-30
FI892185A0 (fi) 1989-05-05
DE3780000D1 (de) 1992-07-30
IE872983L (en) 1988-05-06
ZA878349B (en) 1988-05-03
FI92209C (fi) 1994-10-10
ES2038675T3 (es) 1993-08-01
IE59342B1 (en) 1994-02-09
EP0267741B1 (en) 1992-06-24
WO1988003535A1 (en) 1988-05-19
ATE77628T1 (de) 1992-07-15
GB8626539D0 (en) 1986-12-10
JP2599947B2 (ja) 1997-04-16
JPH02500517A (ja) 1990-02-22

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US5776900A (en) Hemoregulatory peptides
JPS63258490A (ja) カルシトニン遺伝子関連ペプチド誘導体

Legal Events

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