CA1323837C - Solid, rapidly disintegrating dosage form - Google Patents

Solid, rapidly disintegrating dosage form

Info

Publication number
CA1323837C
CA1323837C CA000594713A CA594713A CA1323837C CA 1323837 C CA1323837 C CA 1323837C CA 000594713 A CA000594713 A CA 000594713A CA 594713 A CA594713 A CA 594713A CA 1323837 C CA1323837 C CA 1323837C
Authority
CA
Canada
Prior art keywords
diclofenac
solid
dosage form
permeable
cellulose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000594713A
Other languages
English (en)
French (fr)
Inventor
Ruth Hagemann
Dagmar Wirth
Henri-Julien Bronner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of CA1323837C publication Critical patent/CA1323837C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA000594713A 1988-03-25 1989-03-23 Solid, rapidly disintegrating dosage form Expired - Lifetime CA1323837C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1138/88-7 1988-03-25
CH1138/88A CH675537A5 (ko) 1988-03-25 1988-03-25

Publications (1)

Publication Number Publication Date
CA1323837C true CA1323837C (en) 1993-11-02

Family

ID=4203378

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000594713A Expired - Lifetime CA1323837C (en) 1988-03-25 1989-03-23 Solid, rapidly disintegrating dosage form

Country Status (17)

Country Link
JP (1) JP2774135B2 (ko)
AT (1) AT400299B (ko)
AU (1) AU619261B2 (ko)
BE (1) BE1001706A3 (ko)
CA (1) CA1323837C (ko)
CH (1) CH675537A5 (ko)
DE (1) DE3909520C2 (ko)
DK (1) DK175517B1 (ko)
ES (1) ES2010466A6 (ko)
FR (1) FR2628971B1 (ko)
GB (1) GB2217598B (ko)
GR (1) GR890100182A (ko)
IE (1) IE61221B1 (ko)
IT (1) IT1232823B (ko)
NL (1) NL194999C (ko)
PT (1) PT90104B (ko)
SE (1) SE8901003L (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE509029C2 (sv) * 1988-08-16 1998-11-30 Ss Pharmaceutical Co Långtidsverkande diklofenak-natriumpreparat
GB8824392D0 (en) * 1988-10-18 1988-11-23 Ciba Geigy Ag Dispersible formulation
DE4403943A1 (de) * 1994-02-08 1995-08-10 Hexal Pharma Gmbh Orale Azrneimittelzubereitung mit Diclofenac-Natrium
DE19530575A1 (de) * 1995-08-19 1997-02-20 Gruenenthal Gmbh Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz
JP3950175B2 (ja) * 1997-05-30 2007-07-25 オスモティカ・コーポレイション 多層浸透デバイス
IT1293764B1 (it) * 1997-07-23 1999-03-10 Chiesi Farma Spa Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua
WO2001010405A1 (en) * 1999-08-04 2001-02-15 Ranbaxy Laboratories Limited Hydrodynamically balanced oral drug delivery system
WO2004089343A1 (en) * 2003-04-09 2004-10-21 Ranbaxy Laboratories Limited Water soluble tablets
JP4575654B2 (ja) * 2003-09-05 2010-11-04 エスエス製薬株式会社 溶解性と流動性を改善した医薬組成物
FR2902657B1 (fr) * 2006-06-21 2009-01-16 Virbac Sa Sa Granules ou granules effervescents
WO2009106824A2 (en) * 2008-02-25 2009-09-03 Cipla Limited Pharmaceutical formulations
EP2773204A4 (en) 2011-10-31 2015-05-27 Glaxosmithkline Intellectual Property Ltd Pazopanib FORMULATION
WO2013109224A1 (en) * 2012-01-18 2013-07-25 Mahmut Bilgic Pharmaceutical compositions comprising diclofenac
US11957792B2 (en) * 2012-04-19 2024-04-16 Glatt Ag Taste-masked pharmaceutical compositions containing diclofenac
DE202022100544U1 (de) 2022-01-31 2022-02-16 Ranjitsing Babasing Bayas Neue orale Streifen- oder Dünnfilmform von Diclofenac-Natrium

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4826204A (ko) * 1971-08-11 1973-04-06
GB1371035A (en) * 1971-09-21 1974-10-23 Rolls Royce Method of etching aluminium alloys
US4265874A (en) * 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
EP0052076B1 (de) * 1980-11-12 1985-05-29 Ciba-Geigy Ag Schnellzerfallende Arzneimittel-Presslinge
CH655507B (ko) * 1983-01-12 1986-04-30
DE3446873A1 (de) * 1984-12-21 1986-07-10 Merckle Gmbh Fluessige diclofenac-zubereitungen
CH664085A5 (de) * 1985-02-08 1988-02-15 Ciba Geigy Ag Pharmazeutische praeparate mit analgetischer wirksamkeit, sowie deren herstellung.
IE59106B1 (en) * 1985-05-31 1994-01-12 Warner Lambert Co A therapeutic effervescent composition and a method of preparing the same
LU85943A1 (fr) * 1985-06-12 1987-01-13 Galephar Comprimes pharmaceutiques permettant l'administration aisee de pellets, leur preparation et leur utilisation
DE3607339A1 (de) * 1986-03-06 1987-09-10 Merck Patent Gmbh Pharmazeutische zubereitung
DE3612537C1 (de) * 1986-04-14 1987-07-16 Dispersa Ag Arzneimittel zur Behandlung von Entzuendungen im Auge
EP0243521A1 (de) * 1986-04-30 1987-11-04 Werner Prof. Dr. Thorn Oral verabreichbares Präparat
IT1200178B (it) * 1986-07-23 1989-01-05 Alfa Farmaceutici Spa Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica
US4710384A (en) * 1986-07-28 1987-12-01 Avner Rotman Sustained release tablets made from microcapsules
CH673395A5 (ko) * 1987-01-30 1990-03-15 Ciba Geigy Ag

Also Published As

Publication number Publication date
DE3909520C2 (de) 1998-12-10
SE8901003D0 (sv) 1989-03-21
ES2010466A6 (es) 1989-11-01
DK147189A (da) 1989-09-26
GB2217598A (en) 1989-11-01
IT1232823B (it) 1992-03-05
IE890934L (en) 1989-09-25
IT8947756A0 (it) 1989-03-20
GR890100182A (el) 1990-01-19
CH675537A5 (ko) 1990-10-15
FR2628971B1 (fr) 1994-02-18
FR2628971A1 (fr) 1989-09-29
JPH01283219A (ja) 1989-11-14
SE8901003L (sv) 1989-09-26
AT400299B (de) 1995-11-27
PT90104A (pt) 1989-11-10
AU3163489A (en) 1989-09-28
AU619261B2 (en) 1992-01-23
IE61221B1 (en) 1994-10-19
ATA69089A (de) 1995-04-15
PT90104B (pt) 1994-06-30
GB8906414D0 (en) 1989-05-04
NL194999C (nl) 2003-05-08
BE1001706A3 (fr) 1990-02-13
GB2217598B (en) 1992-01-08
DK175517B1 (da) 2004-11-15
NL8900734A (nl) 1989-10-16
JP2774135B2 (ja) 1998-07-09
DK147189D0 (da) 1989-03-22
DE3909520A1 (de) 1989-10-05

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Legal Events

Date Code Title Description
MKEX Expiry

Effective date: 20101102