CA1242199A - O-substituted pyruvic acid oximes, processes for the preparation thereof and pharmaceutical compositions which contain these new compounds - Google Patents

O-substituted pyruvic acid oximes, processes for the preparation thereof and pharmaceutical compositions which contain these new compounds

Info

Publication number
CA1242199A
CA1242199A CA000386602A CA386602A CA1242199A CA 1242199 A CA1242199 A CA 1242199A CA 000386602 A CA000386602 A CA 000386602A CA 386602 A CA386602 A CA 386602A CA 1242199 A CA1242199 A CA 1242199A
Authority
CA
Canada
Prior art keywords
acid
propionic acid
process according
reacting
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000386602A
Other languages
English (en)
French (fr)
Inventor
Hans P. Wolff
Ruth Heerdt
Manfred Hubner (Deceased)
Hans Kuhnle
Felix H. Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of CA1242199A publication Critical patent/CA1242199A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000386602A 1980-09-26 1981-09-24 O-substituted pyruvic acid oximes, processes for the preparation thereof and pharmaceutical compositions which contain these new compounds Expired CA1242199A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3036281.3 1980-09-26
DE19803036281 DE3036281A1 (de) 1980-09-26 1980-09-26 0-substituierte brenztraubensaeureoxime, verfahren zu ihrer herstellung, ihre verwendung sowie arzneimittel, die diese verbindungen enthalten

Publications (1)

Publication Number Publication Date
CA1242199A true CA1242199A (en) 1988-09-20

Family

ID=6112892

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000386602A Expired CA1242199A (en) 1980-09-26 1981-09-24 O-substituted pyruvic acid oximes, processes for the preparation thereof and pharmaceutical compositions which contain these new compounds

Country Status (14)

Country Link
US (1) US4425360A (oth)
EP (1) EP0048911B1 (oth)
JP (1) JPS5798250A (oth)
AT (1) ATE10622T1 (oth)
CA (1) CA1242199A (oth)
CS (1) CS228907B2 (oth)
DD (1) DD201781A5 (oth)
DE (2) DE3036281A1 (oth)
ES (1) ES505672A0 (oth)
HK (1) HK94891A (oth)
HU (1) HU184967B (oth)
IL (1) IL63894A0 (oth)
SG (1) SG102487G (oth)
SU (2) SU1279526A3 (oth)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3208330A1 (de) * 1982-03-09 1983-09-15 Basf Ag, 6700 Ludwigshafen Alpha-oximinoessigsaeurederivate, ihre herstellung und ihre verwendung zur herstellung von fungizid wirksamen verbindungen
US4584014A (en) * 1984-07-02 1986-04-22 Rohm And Haas Company Ethylideneaminooxyacetic acids and esters
HU197668B (en) * 1984-07-17 1989-05-29 Boehringer Mannheim Gmbh Process for producing pharmaceutical compositions comprising alpha-ketocarboxylic acid hydrazines and oximes
DE3528753A1 (de) * 1985-08-10 1987-02-19 Bayer Ag Substituierte pyrazolin-5-one
US4740524A (en) * 1986-05-16 1988-04-26 Rohm And Haas Company Alpha-halopyruvate oxime
DE3838310A1 (de) * 1988-11-11 1990-05-23 Basf Ag Hydroxylaminderivate
AU620974B2 (en) * 1989-03-31 1992-02-27 Sumitomo Chemical Company, Limited Pyrazole oxime derivatives, production of same and method of controlling extremely harmful pests
JPH03190141A (ja) * 1989-12-12 1991-08-20 Samsung Electron Devices Co Ltd 平板ディスプレー用薄膜トランジスタ及びその製造方法
DE4204206A1 (de) * 1992-02-13 1993-08-19 Basf Ag Mischungen aus optisch aktiven cyclohexenonoximethern, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als herbizide
US5393921A (en) * 1993-07-07 1995-02-28 The Gillette Company Process for synthesizing O-substituted oxime compounds and conversion to the corresponding O-substituted hydroxylamine
ES2083324B1 (es) * 1993-11-12 1996-12-16 Univ Cordoba Procedimiento de obtencion de nitrilos a partir de alfa-cetoacidos.
US5594400A (en) * 1995-01-03 1997-01-14 Siemens Stromberg-Carlson Reed relay
US5570072A (en) * 1995-01-03 1996-10-29 Siemens Stromberg-Carlson Method of establishing a relay contact arrangement
AU2005240524C1 (en) 2004-04-22 2009-12-24 Evoqua Water Technologies Llc Filtration apparatus comprising a membrane bioreactor and a treatment vessel for digesting organic materials
US7591950B2 (en) 2004-11-02 2009-09-22 Siemens Water Technologies Corp. Submerged cross-flow filtration
WO2007044345A2 (en) 2005-10-05 2007-04-19 Siemens Water Technologies Corp. Method and apparatus for treating wastewater
US7455765B2 (en) 2006-01-25 2008-11-25 Siemens Water Technologies Corp. Wastewater treatment system and method
CN112812035B (zh) * 2021-02-01 2022-07-12 闽江学院 一种氟代乙醛-氧-芳基肟类化合物及其合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2470083A (en) * 1946-04-03 1949-05-17 Walter H Hartung Ethers of oximino acid chlorides
US3104258A (en) 1958-09-25 1963-09-17 Fmc Corp Novel synthesis of amino acids
CH511662A (de) 1970-07-16 1971-08-31 Fischer Ag Georg Schnellwechseleinrichtung für Aufspannvorrichtung an Drehmaschinen
BE791214A (fr) * 1972-05-08 1973-05-10 Glaxo Lab Ltd Procede de preparation d'isomeres de derives d'acide hydroxyiminoacetique etherifie purs
US4060686A (en) 1973-12-21 1977-11-29 Janice Bradshaw Cephalosporins having a 7-(carboxy substituted α-etherified oximinoarylacetamido) group
US4052194A (en) 1974-01-24 1977-10-04 Merrill Wilcox Oxime abscission agents
JPS606354B2 (ja) 1976-03-30 1985-02-18 藤沢薬品工業株式会社 ジ置換アルコキシベンゼン誘導体およびその塩類
DE2739380A1 (de) 1977-09-01 1979-03-08 Boehringer Mannheim Gmbh N-substituierte 2-hydrazono-propionsaeure-derivate, verfahren zur herstellung derselben und arzneimittel, die diese enthalten
BE870067A (fr) 1978-09-04 1979-02-28 Ciba Geigy Derives d'oximes pour la protection des cultures
DE3031842A1 (de) 1980-08-23 1982-04-08 Boehringer Mannheim Gmbh, 6800 Mannheim N-substituierte brenztraubensaeurehydrazone, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten

Also Published As

Publication number Publication date
EP0048911A2 (de) 1982-04-07
SU1279526A1 (ru) 1986-12-23
US4425360A (en) 1984-01-10
ES8205762A1 (es) 1982-08-16
ES505672A0 (es) 1982-08-16
EP0048911B1 (de) 1984-12-05
SU1279526A3 (ru) 1986-12-23
SG102487G (en) 1989-01-27
JPS5798250A (en) 1982-06-18
EP0048911A3 (en) 1982-09-29
CS228907B2 (en) 1984-05-14
HU184967B (en) 1984-11-28
SU1217252A3 (ru) 1986-03-07
JPH0226625B2 (oth) 1990-06-12
DE3167634D1 (en) 1985-01-17
HK94891A (en) 1991-12-06
ATE10622T1 (de) 1984-12-15
DE3036281A1 (de) 1982-05-13
DD201781A5 (de) 1983-08-10
IL63894A0 (en) 1981-12-31

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Legal Events

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MKEX Expiry