CA1238043A - Preparations d'acide hyaluronique insolubles dans l'eau et procede de production - Google Patents

Preparations d'acide hyaluronique insolubles dans l'eau et procede de production

Info

Publication number
CA1238043A
CA1238043A CA000460460A CA460460A CA1238043A CA 1238043 A CA1238043 A CA 1238043A CA 000460460 A CA000460460 A CA 000460460A CA 460460 A CA460460 A CA 460460A CA 1238043 A CA1238043 A CA 1238043A
Authority
CA
Canada
Prior art keywords
hyaluronic acid
cross
treatment
effected
linking agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000460460A
Other languages
English (en)
Inventor
Endre A. Balazs
Adolf Leshchiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomatrix Inc
Original Assignee
Biomatrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomatrix Inc filed Critical Biomatrix Inc
Application granted granted Critical
Publication of CA1238043A publication Critical patent/CA1238043A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
CA000460460A 1983-12-15 1984-08-07 Preparations d'acide hyaluronique insolubles dans l'eau et procede de production Expired CA1238043A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56181883A 1983-12-15 1983-12-15
US561,818 1983-12-15
US59807184A 1984-04-09 1984-04-09
US598,071 1984-04-09

Publications (1)

Publication Number Publication Date
CA1238043A true CA1238043A (fr) 1988-06-14

Family

ID=27072762

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000460460A Expired CA1238043A (fr) 1983-12-15 1984-08-07 Preparations d'acide hyaluronique insolubles dans l'eau et procede de production

Country Status (6)

Country Link
AU (1) AU551628B2 (fr)
CA (1) CA1238043A (fr)
DE (1) DE3434104A1 (fr)
FR (1) FR2556728B1 (fr)
GB (1) GB2151244B (fr)
IT (1) IT1178588B (fr)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4713448A (en) * 1985-03-12 1987-12-15 Biomatrix, Inc. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
US5202431A (en) * 1985-07-08 1993-04-13 Fidia, S.P.A. Partial esters of hyaluronic acid
IT1198449B (it) * 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
US4937270A (en) * 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US6174999B1 (en) 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5017229A (en) * 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US6610669B1 (en) 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5527893A (en) * 1987-09-18 1996-06-18 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
AU619760B2 (en) * 1987-12-10 1992-02-06 Genzyme Biosurgery Corporation Hylan preparation and method of recovery thereof from animal tissues
US4888016A (en) * 1988-02-10 1989-12-19 Langerman David W "Spare parts" for use in ophthalmic surgical procedures
ATE126071T1 (de) 1988-12-29 1995-08-15 Chang Ann Lois Diaphragmapumpe.
IT1260154B (it) * 1992-07-03 1996-03-28 Lanfranco Callegaro Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn)
US5550112A (en) * 1992-12-30 1996-08-27 Patent Biopharmaceutics, Inc. Hyaluronic acid-urea pharmaceutical compositions and uses
US5679655A (en) * 1993-08-04 1997-10-21 Patent Biopharmaceutics, Inc. Method of treating lesions resulting from genital herpes with hyaluronic acid-urea pharmaceutical compositions
US5531716A (en) * 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
US6294202B1 (en) 1994-10-06 2001-09-25 Genzyme Corporation Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers
US6214331B1 (en) 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
WO1996039464A1 (fr) * 1995-06-06 1996-12-12 C.R. Bard, Inc. Procede de preparation de dispersions aqueuses de particules de polymeres hydrosolubles et particules ainsi obtenues
US6368356B1 (en) 1996-07-11 2002-04-09 Scimed Life Systems, Inc. Medical devices comprising hydrogel polymers having improved mechanical properties
US6060534A (en) 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
PT939086E (pt) * 1998-02-27 2004-07-30 Stichting Hippomedics Processo para produzir o acido hialuronico reticulado
GB9902652D0 (en) * 1999-02-05 1999-03-31 Fermentech Med Ltd Process
US6521223B1 (en) 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
AU2003234140A1 (en) 2002-04-17 2003-11-03 Genzyme Corporation Aziridine compounds and their use in medical devices
US20050222081A1 (en) * 2002-04-17 2005-10-06 Gianolio Diego A Cross-linked hyaluronate compounds
AU2003901834A0 (en) 2003-04-17 2003-05-01 Clearcoll Pty Ltd Cross-linked polysaccharide compositions
GB2408741B (en) 2003-12-04 2008-06-18 Ind Tech Res Inst Hyaluronic acid derivative with urethane linkage
US8313765B2 (en) 2003-12-04 2012-11-20 Industrial Technology Research Institute Biodegradable hyaluronic acid derivative, biodegradable polymeric micelle composition and pharmaceutical or bioactive composition
CN101068555B (zh) 2004-03-17 2011-07-06 根茨美公司 抗粘连喷雾
US7858107B2 (en) 2004-09-10 2010-12-28 Medtronic Xomed, Inc. Flexible bioresorbable hemostatic packing and stent having a preselectable in-vivo residence time
GB2423252B (en) * 2005-02-18 2007-10-17 Engelhard Lyon Cross-linked polymer of carbohydrate, notably based on polysaccharides, and/or on oligosaccharides and/or on polyols
FR2882366B1 (fr) 2005-02-18 2008-04-18 Coletica Sa Polymere reticule de carbohydrate, notamment a base de polysaccharides et/ou de polyols
US8378091B2 (en) 2005-08-04 2013-02-19 Teijin Limited Cellulose derivative
FR2918377B1 (fr) 2007-07-05 2010-10-08 Estelle Piron Gel co-reticule de polysaccharides
US8691957B2 (en) 2007-09-28 2014-04-08 Shiseido Company, Ltd. Swellable crosslinked hyaluronan powder and method for producing the same
FR2924615B1 (fr) 2007-12-07 2010-01-22 Vivacy Lab Hydrogel cohesif biodegradable.
US10266684B2 (en) 2012-03-12 2019-04-23 Colorado State University Research Foundation Glycosaminoglycan and synthetic polymer materials for blood-contacting applications
IN2014DN07588A (fr) * 2012-03-12 2015-04-24 Univ Colorado State Res Found
ITMI20131193A1 (it) * 2013-07-16 2015-01-17 Ira Srl Acido ialuronico reticolato, processo per la sua preparazione ed applicazioni in ambito estetico
ITUA20161822A1 (it) * 2016-03-18 2017-09-18 Indena Spa Composizioni utili nella prevenzione e/o nel trattamento di patologie del cavo orale, delle prime vie aeree e dell’esofago

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE361320B (fr) * 1972-03-14 1973-10-29 Exploaterings Ab Tbf
US4152170A (en) * 1975-06-18 1979-05-01 Sumitomo Chemical Company, Ltd. Cross-linked pullulan
GB1515963A (en) * 1975-07-15 1978-06-28 Massachusetts Inst Technology Crosslinked collagen-mucopolysaccharide composite materials

Also Published As

Publication number Publication date
IT8423225A1 (it) 1986-04-18
FR2556728A1 (fr) 1985-06-21
DE3434104A1 (de) 1985-08-29
AU551628B2 (en) 1986-05-08
GB8420560D0 (en) 1984-09-19
DE3434104C2 (fr) 1991-06-20
IT1178588B (it) 1987-09-09
AU3337984A (en) 1985-06-20
GB2151244A (en) 1985-07-17
IT8423225A0 (it) 1984-10-18
GB2151244B (en) 1987-01-07
FR2556728B1 (fr) 1987-06-26

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Legal Events

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