CA1192496A - Topical pharmaceutical compositions - Google Patents

Topical pharmaceutical compositions

Info

Publication number
CA1192496A
CA1192496A CA000400470A CA400470A CA1192496A CA 1192496 A CA1192496 A CA 1192496A CA 000400470 A CA000400470 A CA 000400470A CA 400470 A CA400470 A CA 400470A CA 1192496 A CA1192496 A CA 1192496A
Authority
CA
Canada
Prior art keywords
composition
skin
active agent
ester
emulsifier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000400470A
Other languages
English (en)
French (fr)
Inventor
Joachim Franz
Jochen Ziegenmeyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH2327/81A external-priority patent/CH653256A5/de
Priority claimed from CH2631/81A external-priority patent/CH647149A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1192496A publication Critical patent/CA1192496A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA000400470A 1981-04-06 1982-04-05 Topical pharmaceutical compositions Expired CA1192496A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH2327/81 1981-04-06
CH2327/81A CH653256A5 (en) 1981-04-06 1981-04-06 Microemulsion for cutaneous use
CH2631/81A CH647149A5 (en) 1981-04-22 1981-04-22 Composition with 5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole for cutaneous use
CH2631/81 1981-04-22
CH3278/81 1981-05-20
CH327881 1981-05-20

Publications (1)

Publication Number Publication Date
CA1192496A true CA1192496A (en) 1985-08-27

Family

ID=27173625

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000400470A Expired CA1192496A (en) 1981-04-06 1982-04-05 Topical pharmaceutical compositions

Country Status (16)

Country Link
AU (1) AU564570B2 (OSRAM)
CA (1) CA1192496A (OSRAM)
DE (1) DE3212053A1 (OSRAM)
DK (1) DK155882A (OSRAM)
ES (1) ES511169A0 (OSRAM)
FI (1) FI821123L (OSRAM)
FR (1) FR2502951B1 (OSRAM)
GB (2) GB2098865B (OSRAM)
GR (1) GR75462B (OSRAM)
IL (1) IL65424A0 (OSRAM)
IT (1) IT8220611A0 (OSRAM)
MY (1) MY8600571A (OSRAM)
NL (1) NL8201413A (OSRAM)
NZ (1) NZ200232A (OSRAM)
PT (1) PT74703B (OSRAM)
SE (1) SE8202172L (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39128E1 (en) 1997-10-29 2006-06-13 Smithkline Beecham P.L.C. Pleuromutilin derivatives as antimicrobials
US20100081669A1 (en) * 2008-10-01 2010-04-01 Taiwan Biotech Co., Ltd. Pressure sensitive adhesive matrix device or system for the treatment or prevention of onychomycosis or tinea pedis

Families Citing this family (68)

* Cited by examiner, † Cited by third party
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CH655656B (OSRAM) * 1982-10-07 1986-05-15
CA1225594A (en) * 1983-05-20 1987-08-18 Jourge Heller Method for percutaneously administering physiologically active agents
DE3406497A1 (de) * 1984-02-23 1985-09-05 Mueller Bernhard Willi Werner Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung
WO1985003878A1 (en) * 1984-03-01 1985-09-12 Sandoz Ag Pharmaceutical compositions
US5364628A (en) * 1985-05-31 1994-11-15 Sandoz Ltd. Pharmaceutical compositions
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
JPS61280426A (ja) * 1985-06-04 1986-12-11 Ikeda Mohandou:Kk 消炎鎮痛用貼付剤
US4767625A (en) * 1985-09-02 1988-08-30 Kao Corporation Lamella type single phase liquid crystal composition and oil-base cosmetic compositions using the same
US4690774A (en) 1985-09-11 1987-09-01 Chesebrough Pond's Inc. Novel translucent water in oil emulsions
US4797272A (en) 1985-11-15 1989-01-10 Eli Lilly And Company Water-in-oil microemulsions for cosmetic uses
DE3805744C2 (de) * 1987-03-04 1999-09-23 Novartis Ag Phenylcarbamate zur Hemmung der Acetylcholinesterase
IL88076A (en) * 1987-10-28 1993-01-14 Nippon Shinyaku Co Ltd Fat emulsions as drug carriers
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US5342625A (en) * 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
US5332577A (en) * 1988-12-27 1994-07-26 Dermamed Transdermal administration to humans and animals
US5241925A (en) * 1988-12-27 1993-09-07 Dermamed Apparatus and techniques for administering veterinary medicaments
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
DE3908047A1 (de) * 1989-03-13 1990-09-20 Desitin Arzneimittel Gmbh Hochdisperse pharmazeutische zusammensetzung
US5324521A (en) * 1989-12-18 1994-06-28 Dermamed Systems for transdermal administration of medicaments
US5149719A (en) * 1990-04-27 1992-09-22 Minnesota Mining And Manufacturing Company Composition for transdermal penetration of medicaments
FR2673537B1 (fr) 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
DE69229779T2 (de) * 1991-04-19 1999-12-23 Lds Technologies, Inc. Konvertierbare mikroemulsionsverbindungen
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
US6005001A (en) * 1991-05-20 1999-12-21 Novartis Ag (Formerly Sandoz Ag) Pharmaceutical composition
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
GB9111611D0 (en) * 1991-05-30 1991-07-24 Sandoz Ltd Liposomes
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
GB9126209D0 (en) * 1991-12-10 1992-02-12 Orion Yhtymae Oy Drug formulations for parenteral use
AU3326493A (en) * 1991-12-16 1993-07-19 Alza Corporation Improved formulations with hydrophobic permeation enhancers
US5629019A (en) * 1992-02-27 1997-05-13 Alza Corporation Formulations with hydrophobic permeation enhancers
SG45449A1 (en) 1992-05-13 1998-01-16 Sandoz Ltd Ophthalmic compositions
EP1142568A1 (en) 1992-09-25 2001-10-10 Novartis AG Pharmaceutical compositions containing cyclosporins
JPH08505367A (ja) * 1992-10-16 1996-06-11 スミスクライン・ビーチャム・コーポレイション 医薬用エマルジョン組成物
WO1994019000A1 (en) * 1993-02-17 1994-09-01 Smithkline Beecham Corporation Microemulsions containing pharmaceutical compositions
SK164796A3 (en) 1994-11-03 1997-06-04 Dresden Arzneimittel Novel cyclosporine preparation forms for oral administration of and process for producing them
DE4442999A1 (de) 1994-12-02 1996-06-05 Hexal Pharma Gmbh Pharmazeutische Zusammensetzung mit einem aktiven Loratidin-Metaboliten
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
US5958876A (en) * 1996-06-19 1999-09-28 Novartis Ag Cyclosporin-containing pharmaceutical compositions
ATE275963T1 (de) 1997-01-30 2004-10-15 Novartis Pharma Gmbh Ölfreie pharmazeutische zusammensetzung welche cyclosporin enthält
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
IN188719B (OSRAM) * 1997-09-08 2002-11-02 Panacea Biotec Ltd
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US6391282B1 (en) * 1997-11-10 2002-05-21 Flemington Pharmaceutical Corp. Antihistamine sprays and ointments for relief of delayed contact dermatitis
DE19825856A1 (de) * 1998-06-10 1999-12-16 Labtec Gmbh Topische Arzneimittelzubereitung
US6638522B1 (en) 1998-12-11 2003-10-28 Pharmasolutions, Inc. Microemulsion concentrate composition of cyclosporin
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US7244703B2 (en) 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
WO2004112723A2 (en) * 2003-06-20 2004-12-29 Ronald Aung-Din Tropical therapy for the treatment of migraines, muscle sprains, muscle spasm, spasticity and related conditions
ES2348303T3 (es) 2003-12-08 2010-12-02 Cpex Pharmaceuticals, Inc. Composiciones farmacauticas y procedimientos de tratamiento con insulina.
US7740875B2 (en) 2004-10-08 2010-06-22 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US20060078580A1 (en) 2004-10-08 2006-04-13 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
US20170246187A1 (en) 2014-08-28 2017-08-31 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US20160361322A1 (en) 2015-06-15 2016-12-15 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy
AU2019308326B2 (en) 2018-07-20 2025-07-31 Lipocine Inc. Liver disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH570401A5 (OSRAM) * 1972-05-09 1975-12-15 Wander Ag Dr A
GB1559811A (en) * 1975-07-28 1980-01-30 Sandoz Ltd Pharmaceutically active benzothiadiazole derivatives
CH632268A5 (de) * 1977-01-14 1982-09-30 Sandoz Ag Verfahren zur herstellung von neuen heterocyclylaminoderivaten.

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39128E1 (en) 1997-10-29 2006-06-13 Smithkline Beecham P.L.C. Pleuromutilin derivatives as antimicrobials
USRE43390E1 (en) 1997-10-29 2012-05-15 Glaxosmithkline Llc Pleuromutilin derivatives as antimicrobials
US20100081669A1 (en) * 2008-10-01 2010-04-01 Taiwan Biotech Co., Ltd. Pressure sensitive adhesive matrix device or system for the treatment or prevention of onychomycosis or tinea pedis
US9308203B2 (en) * 2008-10-01 2016-04-12 Taiwan Biotech Co., Ltd. Pressure sensitive adhesive matrix device or system for the treatment or prevention of onychomycosis or tinea pedis

Also Published As

Publication number Publication date
FR2502951B1 (fr) 1985-12-06
GB2098865B (en) 1985-12-18
DE3212053A1 (de) 1982-10-21
GB8408654D0 (en) 1984-05-16
AU564570B2 (en) 1987-08-20
IT8220611A0 (it) 1982-04-06
SE8202172L (sv) 1982-10-07
FR2502951A1 (fr) 1982-10-08
FI821123A7 (fi) 1982-10-07
GR75462B (OSRAM) 1984-07-20
NL8201413A (nl) 1982-11-01
FI821123L (fi) 1982-10-07
PT74703B (en) 1984-05-30
NZ200232A (en) 1985-08-16
PT74703A (en) 1982-05-01
ES8308698A1 (es) 1983-10-01
DK155882A (da) 1982-12-10
GB2098865A (en) 1982-12-01
GB2148711B (en) 1985-12-18
IL65424A0 (en) 1982-07-30
GB2148711A (en) 1985-06-05
ES511169A0 (es) 1983-10-01
MY8600571A (en) 1986-12-31
AU8233482A (en) 1982-10-14
FI821123A0 (fi) 1982-03-31

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Legal Events

Date Code Title Description
MKEX Expiry