CA1178583A - 1,7-dihydro-pyrrolo ¬3,4-e| ¬1,4|diazepin- 2(1h)-one derivatives - Google Patents

1,7-dihydro-pyrrolo ¬3,4-e| ¬1,4|diazepin- 2(1h)-one derivatives

Info

Publication number
CA1178583A
CA1178583A CA000404438A CA404438A CA1178583A CA 1178583 A CA1178583 A CA 1178583A CA 000404438 A CA000404438 A CA 000404438A CA 404438 A CA404438 A CA 404438A CA 1178583 A CA1178583 A CA 1178583A
Authority
CA
Canada
Prior art keywords
compound
diazepin
dihydro
dimethyl
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000404438A
Other languages
English (en)
French (fr)
Inventor
Luigi Mariani
Giorgio Tarzia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA filed Critical Gruppo Lepetit SpA
Application granted granted Critical
Publication of CA1178583A publication Critical patent/CA1178583A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA000404438A 1981-06-04 1982-06-03 1,7-dihydro-pyrrolo ¬3,4-e| ¬1,4|diazepin- 2(1h)-one derivatives Expired CA1178583A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8117184 1981-06-04
GB8117184 1981-06-04

Publications (1)

Publication Number Publication Date
CA1178583A true CA1178583A (en) 1984-11-27

Family

ID=10522285

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000404438A Expired CA1178583A (en) 1981-06-04 1982-06-03 1,7-dihydro-pyrrolo ¬3,4-e| ¬1,4|diazepin- 2(1h)-one derivatives

Country Status (14)

Country Link
US (1) US4402970A (en:Method)
EP (1) EP0066762B1 (en:Method)
JP (1) JPS57212184A (en:Method)
AT (1) ATE16594T1 (en:Method)
AU (1) AU551695B2 (en:Method)
CA (1) CA1178583A (en:Method)
DE (1) DE3267543D1 (en:Method)
DK (1) DK160307C (en:Method)
ES (1) ES8307809A1 (en:Method)
GR (1) GR76455B (en:Method)
IE (1) IE53343B1 (en:Method)
IL (1) IL65896A (en:Method)
PH (1) PH18767A (en:Method)
ZA (1) ZA823701B (en:Method)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4508730A (en) * 1982-09-08 1985-04-02 Gruppo Lepetit S.P.A. 1,7-Dihydro-pyrrolo[3,4-e][1,4]diazepin-2(3H)-one derivatives a process for preparing them and their use as anticonvulsant and anti-anxiety agents
US4517195A (en) * 1984-07-02 1985-05-14 Hoechst-Roussel Pharmaceuticals Inc. Pyrrolo[1,2-b][1,2,5]triazepines and pharmaceutical compositions thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1300114B (de) * 1963-05-29 1969-07-31 American Home Prod Verfahren zur Herstellung von 5-Chlor-2-(2'-hydroxylamino-acetamido)-benzophenon
NL298071A (en:Method) * 1963-06-04
US3553207A (en) * 1968-12-16 1971-01-05 Parke Davis & Co Phenylpyrazolodiazepinone compounds
US3553210A (en) * 1968-12-16 1971-01-05 Parke Davis & Co 3-methyl-8-phenylpyrazolo(4,3-e)(1,4)diazepin-5(1h)-one, 7-oxide compounds
GB1433103A (en) * 1974-03-20 1976-04-22 Lepetit Spa Pharmacologically active pyrrolodiazepines

Also Published As

Publication number Publication date
EP0066762A3 (en) 1983-04-27
EP0066762A2 (en) 1982-12-15
IE53343B1 (en) 1988-10-26
AU551695B2 (en) 1986-05-08
ES512811A0 (es) 1983-08-01
DK245182A (da) 1982-12-05
JPH0378397B2 (en:Method) 1991-12-13
EP0066762B1 (en) 1985-11-21
PH18767A (en) 1985-09-20
US4402970A (en) 1983-09-06
AU8387082A (en) 1982-12-09
ES8307809A1 (es) 1983-08-01
ATE16594T1 (de) 1985-12-15
DK160307B (da) 1991-02-25
ZA823701B (en) 1983-03-30
DK160307C (da) 1991-07-29
IL65896A (en) 1985-08-30
GR76455B (en:Method) 1984-08-10
IE821336L (en) 1982-12-04
DE3267543D1 (de) 1986-01-02
JPS57212184A (en) 1982-12-27

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Legal Events

Date Code Title Description
MKEC Expiry (correction)
MKEX Expiry