CA1175429A - 1-substituted-3-(substituted - amino)-5-(pyridinyl)- 1h-pyrazolo[3,4-b]pyridines, their preparation and use as cardiotonics - Google Patents

1-substituted-3-(substituted - amino)-5-(pyridinyl)- 1h-pyrazolo[3,4-b]pyridines, their preparation and use as cardiotonics

Info

Publication number
CA1175429A
CA1175429A CA000401733A CA401733A CA1175429A CA 1175429 A CA1175429 A CA 1175429A CA 000401733 A CA000401733 A CA 000401733A CA 401733 A CA401733 A CA 401733A CA 1175429 A CA1175429 A CA 1175429A
Authority
CA
Canada
Prior art keywords
pyridinyl
pyrazolo
pyridin
methyl
amine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000401733A
Other languages
English (en)
French (fr)
Inventor
George Y. Lesher
Monte D. Gruett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Application granted granted Critical
Publication of CA1175429A publication Critical patent/CA1175429A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
CA000401733A 1981-04-28 1982-04-27 1-substituted-3-(substituted - amino)-5-(pyridinyl)- 1h-pyrazolo[3,4-b]pyridines, their preparation and use as cardiotonics Expired CA1175429A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/258,363 US4361568A (en) 1981-04-28 1981-04-28 5-(Pyridinyl)-1H-pyrazolo[3,4-b]pyridin-3-amines and their cardiotonic use
US258,363 1988-12-27

Publications (1)

Publication Number Publication Date
CA1175429A true CA1175429A (en) 1984-10-02

Family

ID=22980254

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000401733A Expired CA1175429A (en) 1981-04-28 1982-04-27 1-substituted-3-(substituted - amino)-5-(pyridinyl)- 1h-pyrazolo[3,4-b]pyridines, their preparation and use as cardiotonics

Country Status (13)

Country Link
US (1) US4361568A (enExample)
EP (1) EP0063754A1 (enExample)
JP (1) JPS57181088A (enExample)
KR (1) KR830010111A (enExample)
AU (1) AU8283782A (enExample)
CA (1) CA1175429A (enExample)
DK (1) DK178382A (enExample)
FI (1) FI821332L (enExample)
GR (1) GR76131B (enExample)
IL (1) IL65555A (enExample)
NO (1) NO821314L (enExample)
PT (1) PT74783B (enExample)
ZA (1) ZA822458B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666913A (en) * 1985-11-22 1987-05-19 William H. Rorer, Inc. Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
AU2001287898A1 (en) 2000-09-22 2002-04-02 Stephen Garland Pyrazolopyridines and pyrazolopyridazines as antidiabetics
ATE481402T1 (de) 2003-02-27 2010-10-15 Palau Pharma Sa Pyrazolopyridin-derivate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2232038A1 (de) * 1972-06-30 1974-01-10 Hoechst Ag 3-amino-1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine, ihre herstellung und verwendung
US4265895A (en) * 1980-03-17 1981-05-05 Sterling Drug Inc. 1,2-Dihydro-5-pyridinyl-3H-pyrazolo[3,4-b]pyridin-3-ones and their use as cardiotonics
US4264603A (en) * 1980-03-17 1981-04-28 Sterling Drug Inc. 5-(Pyridinyl)-1H-pyrazolo[3,4-b]pyridine-3-amines, their use as cardiotonics and their preparation

Also Published As

Publication number Publication date
AU8283782A (en) 1982-11-04
US4361568A (en) 1982-11-30
ZA822458B (en) 1983-03-30
EP0063754A1 (en) 1982-11-03
JPS57181088A (en) 1982-11-08
PT74783A (en) 1982-05-01
PT74783B (en) 1983-11-07
KR830010111A (ko) 1983-12-26
GR76131B (enExample) 1984-08-03
FI821332A7 (fi) 1982-10-29
FI821332A0 (fi) 1982-04-16
NO821314L (no) 1982-10-29
DK178382A (da) 1982-10-29
IL65555A0 (en) 1982-07-30
FI821332L (fi) 1982-10-29
IL65555A (en) 1985-02-28

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Legal Events

Date Code Title Description
MKEC Expiry (correction)
MKEX Expiry