CA1161434A - Acylaminoquinazoline derivatives, a process for their preparation and a pharmaceutical composition containing them - Google Patents

Acylaminoquinazoline derivatives, a process for their preparation and a pharmaceutical composition containing them

Info

Publication number
CA1161434A
CA1161434A CA000390963A CA390963A CA1161434A CA 1161434 A CA1161434 A CA 1161434A CA 000390963 A CA000390963 A CA 000390963A CA 390963 A CA390963 A CA 390963A CA 1161434 A CA1161434 A CA 1161434A
Authority
CA
Canada
Prior art keywords
group
piperazinyl
methylpropanoyl
amino
acetylthio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000390963A
Other languages
English (en)
French (fr)
Inventor
Yasunobu Sato
Hiroshi Fukumi
Hiroyuki Koike
Nobuaki Kitahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of CA1161434A publication Critical patent/CA1161434A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA000390963A 1980-11-26 1981-11-26 Acylaminoquinazoline derivatives, a process for their preparation and a pharmaceutical composition containing them Expired CA1161434A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP166327/80 1980-11-26
JP55166327A JPS5793977A (en) 1980-11-26 1980-11-26 Acylaminoquinazoline derivative and its preparation

Publications (1)

Publication Number Publication Date
CA1161434A true CA1161434A (en) 1984-01-31

Family

ID=15829296

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000390963A Expired CA1161434A (en) 1980-11-26 1981-11-26 Acylaminoquinazoline derivatives, a process for their preparation and a pharmaceutical composition containing them

Country Status (9)

Country Link
US (1) US4495188A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0053047B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5793977A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1161434A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3164469D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8304120A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI813801A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH18595A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA818176B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS236097B1 (en) * 1983-06-01 1985-05-15 Jan Koenig Acylderivatives of 2-piperazinochinazoline and method of their preparation
CA2164330A1 (en) * 1993-06-04 1994-12-22 Paul E. Share Polymerizable compounds
US5922820A (en) * 1993-06-04 1999-07-13 Henkel Corporation Polymerizable compounds
US5565567A (en) * 1993-06-04 1996-10-15 Henkel Corporation. Polymerizable N,N'-substituted piperazine acrylamide compounds
US5563214A (en) * 1994-08-09 1996-10-08 Henkel Corporation Aqueous compositions containing polymerizable surfactant compounds
CA2232138A1 (en) * 1995-09-29 1997-04-03 William C. Lumma Alpha 1b adrenergic receptor antagonists
US5756742A (en) * 1995-12-22 1998-05-26 Henkel Corporation Polymerizable compounds
WO2005121094A1 (en) * 2004-06-09 2005-12-22 Pfizer Limited Piperazine and piperidine derivatives as anti-hiv-agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3574212A (en) * 1968-02-02 1971-04-06 Pfizer Quinazolinylureas
US3663706A (en) * 1969-09-29 1972-05-16 Pfizer Use of 2,4-diaminoquinazolines as hypotensive agents
US3971783A (en) * 1973-03-07 1976-07-27 Pfizer Inc. 4-Aminoquinazoline derivatives as cardiac stimulants
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4001238A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company 1,3,4-oxadiazole amides
US4001237A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company Oxazole, isoxazole, thiazole and isothiazole amides
DE2623846A1 (de) * 1976-05-28 1977-12-15 Hoechst Ag 4-chinazolinyl-guanidine und verfahren zu ihrer herstellung
GR69201B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1976-08-06 1982-05-06 Pfizer
US4062844A (en) * 1976-09-20 1977-12-13 Pfizer Inc. Process for preparing hypotensive 2-(4-aroylpiperazin-1-yl)-amino-6,7-dimethoxyquinazolines
US4192945A (en) * 1978-12-07 1980-03-11 E. R. Squibb & Sons, Inc. Process for preparing proline and homoproline derivatives

Also Published As

Publication number Publication date
JPS6330910B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-06-21
FI813801L (fi) 1982-05-27
EP0053047B1 (en) 1984-06-27
ZA818176B (en) 1982-11-24
ES507482A0 (es) 1983-02-16
JPS5793977A (en) 1982-06-11
ES8304120A1 (es) 1983-02-16
DE3164469D1 (en) 1984-08-02
PH18595A (en) 1985-08-15
US4495188A (en) 1985-01-22
FI813801A7 (fi) 1982-05-27
EP0053047A1 (en) 1982-06-02

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Legal Events

Date Code Title Description
MKEX Expiry