CA1153366A - BIS- AND MONO-QUATERNARY AMMONIUM DERIVATIVES OF 2.beta., 16.beta.-DIPIPERIDINO-5.alpha.-ANDROSTANES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS - Google Patents

BIS- AND MONO-QUATERNARY AMMONIUM DERIVATIVES OF 2.beta., 16.beta.-DIPIPERIDINO-5.alpha.-ANDROSTANES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS

Info

Publication number
CA1153366A
CA1153366A CA000366536A CA366536A CA1153366A CA 1153366 A CA1153366 A CA 1153366A CA 000366536 A CA000366536 A CA 000366536A CA 366536 A CA366536 A CA 366536A CA 1153366 A CA1153366 A CA 1153366A
Authority
CA
Canada
Prior art keywords
beta
alpha
piperidino
androstane
isobutyrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000366536A
Other languages
English (en)
French (fr)
Inventor
Jan Kelder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Application granted granted Critical
Publication of CA1153366A publication Critical patent/CA1153366A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CA000366536A 1979-12-12 1980-12-11 BIS- AND MONO-QUATERNARY AMMONIUM DERIVATIVES OF 2.beta., 16.beta.-DIPIPERIDINO-5.alpha.-ANDROSTANES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS Expired CA1153366A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB79.42883 1979-12-12
GB7942883 1979-12-12

Publications (1)

Publication Number Publication Date
CA1153366A true CA1153366A (en) 1983-09-06

Family

ID=10509800

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000366536A Expired CA1153366A (en) 1979-12-12 1980-12-11 BIS- AND MONO-QUATERNARY AMMONIUM DERIVATIVES OF 2.beta., 16.beta.-DIPIPERIDINO-5.alpha.-ANDROSTANES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS

Country Status (12)

Country Link
US (1) US4348390A (enExample)
EP (1) EP0032261B1 (enExample)
JP (1) JPH026360B2 (enExample)
AU (1) AU534992B2 (enExample)
CA (1) CA1153366A (enExample)
DE (1) DE3065088D1 (enExample)
DK (1) DK158741C (enExample)
ES (1) ES497724A0 (enExample)
FI (1) FI66394C (enExample)
HU (1) HU185865B (enExample)
IE (1) IE50675B1 (enExample)
WO (1) WO1981001710A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE53463B1 (en) * 1981-06-15 1988-11-23 Akzo Nv Mono-and bisquaternary ammonium derivatives of 2 beta,16 beta-d-amino-5 alpha-androstane derivatives and pharmaceutical preparations containing same
US4726275A (en) * 1983-05-10 1988-02-23 Synthaxe Limited Electronic musical instrument
US5418226A (en) * 1992-04-22 1995-05-23 Akzo N.V. Monoquaternary 2,16-bispiperidinylandrostane derivatives
US5926516A (en) * 1995-05-24 1999-07-20 Siemens Aktiengesellschaft Absorption structure for absorbing neutrons and method for producing an absorption structure
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
US5990124A (en) * 1997-10-24 1999-11-23 Gyermek; Laszlo Neuromuscular relaxants
CN116925171B (zh) * 2023-07-10 2025-06-27 时森海(杭州)医药科技有限公司 含环丙甲基甾体类季铵盐化合物、中间体及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
GB1454749A (en) * 1972-11-29 1976-11-03 Akzo Nv 2beta, 16beta-diamino-androstanes and their preparation
HU172522B (hu) * 1975-08-01 1978-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 2beta, 16beta-diamino-androstana i ikh chetvertichnykh solej
EP0008824B1 (en) * 1978-09-05 1982-04-28 Akzo N.V. Acid addition salts of 16-beta-monoquaternary ammonium derivatives of 2-beta, 16-beta-bis-piperidino-androstanes and pharmaceutical preparations containing same

Also Published As

Publication number Publication date
US4348390A (en) 1982-09-07
EP0032261B1 (en) 1983-09-28
DK158741B (da) 1990-07-09
FI811857L (fi) 1981-06-15
JPH026360B2 (enExample) 1990-02-08
ES8204443A1 (es) 1982-05-01
FI66394B (fi) 1984-06-29
EP0032261A1 (en) 1981-07-22
HU185865B (en) 1985-04-28
ES497724A0 (es) 1982-05-01
WO1981001710A1 (fr) 1981-06-25
AU534992B2 (en) 1984-02-23
IE50675B1 (en) 1986-06-11
DK260881A (da) 1981-06-25
FI66394C (fi) 1984-10-10
DE3065088D1 (en) 1983-11-03
DK158741C (da) 1990-11-26
IE802566L (en) 1981-06-12
JPS56501761A (enExample) 1981-12-03
AU6640581A (en) 1981-07-06

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Legal Events

Date Code Title Description
MKEX Expiry