CA1140934A - Aminobenzoic acid derivatives, their preparation and their use as pharmaceutical compositions or as intermediates - Google Patents

Aminobenzoic acid derivatives, their preparation and their use as pharmaceutical compositions or as intermediates

Info

Publication number
CA1140934A
CA1140934A CA000355165A CA355165A CA1140934A CA 1140934 A CA1140934 A CA 1140934A CA 000355165 A CA000355165 A CA 000355165A CA 355165 A CA355165 A CA 355165A CA 1140934 A CA1140934 A CA 1140934A
Authority
CA
Canada
Prior art keywords
group
carbon atoms
amino
bromo
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000355165A
Other languages
English (en)
French (fr)
Inventor
Klaus Noll
Johannes Keck
Helmut Pieper
Gerd Kruger
Helmut Ballhause
Eckhart Bauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Application granted granted Critical
Publication of CA1140934A publication Critical patent/CA1140934A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
CA000355165A 1979-06-30 1980-06-30 Aminobenzoic acid derivatives, their preparation and their use as pharmaceutical compositions or as intermediates Expired CA1140934A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19792926471 DE2926471A1 (de) 1979-06-30 1979-06-30 Neue aminobenzoesaeurederivate, deren herstellung und deren verwendung als arzneimittel oder zwischenprodukte
DEP2926471.9 1979-06-30

Publications (1)

Publication Number Publication Date
CA1140934A true CA1140934A (en) 1983-02-08

Family

ID=6074590

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000355165A Expired CA1140934A (en) 1979-06-30 1980-06-30 Aminobenzoic acid derivatives, their preparation and their use as pharmaceutical compositions or as intermediates

Country Status (10)

Country Link
JP (1) JPS5610154A (el)
AT (1) AT370085B (el)
CA (1) CA1140934A (el)
DE (1) DE2926471A1 (el)
DK (1) DK279380A (el)
ES (1) ES492843A0 (el)
FI (1) FI802048A (el)
GR (1) GR69273B (el)
NO (1) NO801930L (el)
PT (1) PT71452B (el)

Also Published As

Publication number Publication date
GR69273B (el) 1982-05-13
DK279380A (da) 1980-12-31
PT71452A (de) 1980-07-01
ES8201536A1 (es) 1981-11-16
JPS5610154A (en) 1981-02-02
ATA306380A (de) 1982-07-15
AT370085B (de) 1983-02-25
FI802048A (fi) 1980-12-31
DE2926471A1 (de) 1981-01-15
NO801930L (no) 1981-01-02
ES492843A0 (es) 1981-11-16
PT71452B (de) 1981-10-23

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Legal Events

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