CA1135277A - 3-hydroxy-4-(hydroxymethyl)benzoic acid and alkyl esters thereof - Google Patents

3-hydroxy-4-(hydroxymethyl)benzoic acid and alkyl esters thereof

Info

Publication number
CA1135277A
CA1135277A CA000331879A CA331879A CA1135277A CA 1135277 A CA1135277 A CA 1135277A CA 000331879 A CA000331879 A CA 000331879A CA 331879 A CA331879 A CA 331879A CA 1135277 A CA1135277 A CA 1135277A
Authority
CA
Canada
Prior art keywords
hydrates
pharmaceutically acceptable
compound
salts
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000331879A
Other languages
English (en)
French (fr)
Inventor
Hamao Umezawa
Ikuo Matsumoto
Tomio Takeuchi
Junji Yoshizawa
Takuzo Yamamoto
Takaaki Aoyagi
Masaaki Hosoi
Masaaki Ishizuka
Hajime Morishima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Banyu Phamaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Phamaceutical Co Ltd filed Critical Banyu Phamaceutical Co Ltd
Application granted granted Critical
Publication of CA1135277A publication Critical patent/CA1135277A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000331879A 1978-07-17 1979-07-16 3-hydroxy-4-(hydroxymethyl)benzoic acid and alkyl esters thereof Expired CA1135277A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP86178/78 1978-07-17
JP8617878A JPS5513238A (en) 1978-07-17 1978-07-17 Novel compound having immunoactivating action, its preparation and application

Publications (1)

Publication Number Publication Date
CA1135277A true CA1135277A (en) 1982-11-09

Family

ID=13879498

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000331879A Expired CA1135277A (en) 1978-07-17 1979-07-16 3-hydroxy-4-(hydroxymethyl)benzoic acid and alkyl esters thereof

Country Status (7)

Country Link
US (1) US4335250A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5513238A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1135277A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2928594C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2431480A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2025410B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1165981B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61233649A (ja) * 1978-07-17 1986-10-17 Banyu Pharmaceut Co Ltd 免疫賦活作用を有する新規化合物およびその製法
US4842862A (en) * 1986-07-03 1989-06-27 International Minerals & Chemical Corp. Immunostimulating agents
US5003055A (en) * 1987-09-25 1991-03-26 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Anthracycline derivatives having inhibitory activity against reverse transcriptase of human immunodeficiency virus
JP3208437B2 (ja) * 1995-04-10 2001-09-10 大鵬薬品工業株式会社 癌転移抑制剤
EP1781300A1 (en) 2004-07-16 2007-05-09 ProteoSys AG Muscarinic antagonists with parp and sir modulatng activity as agents for inflammatory diseases
US8263681B2 (en) * 2006-12-28 2012-09-11 3M Innovative Properties Company Dental compositions with natural tooth fluorescence
US20100297588A1 (en) * 2007-11-02 2010-11-25 3M Innovative Properties Company Dental compositions with natural tooth fluorescence and methods
WO2010081823A1 (en) 2009-01-13 2010-07-22 Proteosys Ag Pirenzepine as otoprotective agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1073824A (en) * 1965-04-06 1967-06-28 Ici Ltd Separation of a 4:4-bipyridylium salt from a mixture containing it
US3496211A (en) * 1966-05-19 1970-02-17 Geigy Chem Corp Preparation of cyanoalkylated phenols by the reaction of a metal cyanide and hydroxy benzyl phenols
JPS5444632A (en) * 1977-09-12 1979-04-09 Microbial Chem Res Found Novel compound with immunization activity and its preparation and application

Also Published As

Publication number Publication date
JPS5513238A (en) 1980-01-30
FR2431480A1 (fr) 1980-02-15
US4335250A (en) 1982-06-15
GB2025410B (en) 1982-11-17
IT7909486A0 (it) 1979-07-16
FR2431480B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-12-16
GB2025410A (en) 1980-01-23
DE2928594C2 (de) 1982-09-02
JPS6319499B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-04-22
DE2928594A1 (de) 1980-02-07
IT1165981B (it) 1987-04-29

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Legal Events

Date Code Title Description
MKEX Expiry