CA1112162A - Microaggregats de proteines pour la scannographie du systeme reticuloendothelial - Google Patents

Microaggregats de proteines pour la scannographie du systeme reticuloendothelial

Info

Publication number
CA1112162A
CA1112162A CA319,662A CA319662A CA1112162A CA 1112162 A CA1112162 A CA 1112162A CA 319662 A CA319662 A CA 319662A CA 1112162 A CA1112162 A CA 1112162A
Authority
CA
Canada
Prior art keywords
microaggregates
albumin
reducing metal
particle size
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA319,662A
Other languages
English (en)
Inventor
Eugene L. Saklad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lantheus Medical Imaging Inc
Original Assignee
New England Nuclear Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/898,292 external-priority patent/US4226846A/en
Application filed by New England Nuclear Corp filed Critical New England Nuclear Corp
Application granted granted Critical
Publication of CA1112162A publication Critical patent/CA1112162A/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/081—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the protein being an albumin, e.g. human serum albumin [HSA], bovine serum albumin [BSA], ovalbumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A61K51/1255—Granulates, agglomerates, microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA319,662A 1978-04-20 1979-01-15 Microaggregats de proteines pour la scannographie du systeme reticuloendothelial Expired CA1112162A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US898,292 1978-04-20
US05/898,292 US4226846A (en) 1977-04-01 1978-04-20 Albumin microaggregates for radioactive scanning of reticuloendothelial systems

Publications (1)

Publication Number Publication Date
CA1112162A true CA1112162A (fr) 1981-11-10

Family

ID=25409231

Family Applications (1)

Application Number Title Priority Date Filing Date
CA319,662A Expired CA1112162A (fr) 1978-04-20 1979-01-15 Microaggregats de proteines pour la scannographie du systeme reticuloendothelial

Country Status (2)

Country Link
CA (1) CA1112162A (fr)
CH (1) CH644019A5 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6730286B2 (en) * 2001-02-28 2004-05-04 Bracco Diagnostics, Inc. Manufacturing process to control particle size
TWI571266B (zh) * 2014-09-02 2017-02-21 行政院原子能委員會核能研究所 快速製備放射性同位素標幟人類血清白蛋白微球體之方法

Also Published As

Publication number Publication date
CH644019A5 (en) 1984-07-13

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