CA1102790A - 3,7-disubstituted cephalosporins and preparation thereof - Google Patents
3,7-disubstituted cephalosporins and preparation thereofInfo
- Publication number
- CA1102790A CA1102790A CA278,851A CA278851A CA1102790A CA 1102790 A CA1102790 A CA 1102790A CA 278851 A CA278851 A CA 278851A CA 1102790 A CA1102790 A CA 1102790A
- Authority
- CA
- Canada
- Prior art keywords
- acid
- cephem
- carboxylic acid
- amino
- chemical equivalent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB21032/76A GB1579532A (en) | 1976-05-21 | 1976-05-21 | Cephalosporins |
| GB21032/76 | 1976-05-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1102790A true CA1102790A (en) | 1981-06-09 |
Family
ID=10156029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA278,851A Expired CA1102790A (en) | 1976-05-21 | 1977-05-20 | 3,7-disubstituted cephalosporins and preparation thereof |
Country Status (22)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017004077A1 (en) * | 2015-06-29 | 2017-01-05 | Duke University | Antimicrobial prochelators to target drug-resistant bacteria and methods of making and using the same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL38099A (en) * | 1970-12-17 | 1976-01-30 | Smith Kline French Lab | 3-heterocyclyl thiomethylcephalosporins |
| US4007173A (en) * | 1973-05-07 | 1977-02-08 | Smithkline Corporation | α-amino-α-(ureidophenyl)acetamidocephalosporins |
| DE2359544A1 (de) * | 1973-11-29 | 1975-10-30 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
| US3960849A (en) * | 1974-03-13 | 1976-06-01 | E. R. Squibb & Sons, Inc. | Amino-1,2,4-oxadiazolyl-3-acetyl cephalosporins |
| DE2512284A1 (de) * | 1974-03-28 | 1975-10-09 | Fujisawa Pharmaceutical Co | Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel |
-
1976
- 1976-05-21 GB GB21032/76A patent/GB1579532A/en not_active Expired
-
1977
- 1977-05-11 AU AU25071/77A patent/AU509448B2/en not_active Expired
- 1977-05-12 NL NL7705262A patent/NL7705262A/xx not_active Application Discontinuation
- 1977-05-13 ZA ZA00772859A patent/ZA772859B/xx unknown
- 1977-05-16 US US05/797,606 patent/US4148996A/en not_active Expired - Lifetime
- 1977-05-16 AT AT348977A patent/AT355719B/de not_active IP Right Cessation
- 1977-05-16 CS CS773205A patent/CS199676B2/cs unknown
- 1977-05-16 NZ NZ184110A patent/NZ184110A/xx unknown
- 1977-05-17 YU YU01230/77A patent/YU123077A/xx unknown
- 1977-05-17 FR FR7715045A patent/FR2424922A1/fr active Granted
- 1977-05-18 NO NO771744A patent/NO771744L/no unknown
- 1977-05-18 DK DK216877A patent/DK216877A/da unknown
- 1977-05-18 DE DE2722666A patent/DE2722666C2/de not_active Expired
- 1977-05-18 SE SE7705934A patent/SE433851B/xx unknown
- 1977-05-19 IL IL52123A patent/IL52123A/xx unknown
- 1977-05-20 GR GR53525A patent/GR73013B/el unknown
- 1977-05-20 CH CH625577A patent/CH639095A5/de not_active IP Right Cessation
- 1977-05-20 CA CA278,851A patent/CA1102790A/en not_active Expired
- 1977-05-20 SU SU772483403A patent/SU799669A3/ru active
- 1977-05-20 JP JP5862277A patent/JPS52142093A/ja active Pending
- 1977-05-20 BE BE177745A patent/BE854845A/xx not_active IP Right Cessation
- 1977-05-20 HU HU77SO1190A patent/HU174072B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU174072B (hu) | 1979-10-28 |
| IL52123A0 (en) | 1977-07-31 |
| YU123077A (en) | 1982-10-31 |
| DE2722666C2 (de) | 1982-04-15 |
| NL7705262A (nl) | 1977-11-23 |
| JPS52142093A (en) | 1977-11-26 |
| ATA348977A (de) | 1979-08-15 |
| ZA772859B (en) | 1978-04-26 |
| GR73013B (US20090163788A1-20090625-C00002.png) | 1984-01-25 |
| GB1579532A (en) | 1980-11-19 |
| SE7705934L (sv) | 1977-11-22 |
| DK216877A (da) | 1977-11-22 |
| FR2424922A1 (fr) | 1979-11-30 |
| SU799669A3 (ru) | 1981-01-23 |
| CS199676B2 (en) | 1980-07-31 |
| BE854845A (fr) | 1977-11-21 |
| SE433851B (sv) | 1984-06-18 |
| NO771744L (no) | 1977-11-22 |
| AU509448B2 (en) | 1980-05-15 |
| US4148996A (en) | 1979-04-10 |
| CH639095A5 (de) | 1983-10-31 |
| AU2507177A (en) | 1978-11-16 |
| AT355719B (de) | 1980-03-25 |
| FR2424922B1 (US20090163788A1-20090625-C00002.png) | 1983-07-08 |
| DE2722666A1 (de) | 1977-12-01 |
| NZ184110A (en) | 1979-08-31 |
| IL52123A (en) | 1980-11-30 |
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| US3843640A (en) | 2-spirocyclopropyl-3-cephem antibiotics | |
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| JPS6156238B2 (US20090163788A1-20090625-C00002.png) | ||
| JPH093074A (ja) | セファロスポリン化合物、その用途および中間体化合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |