CA1099546A - Contact lens - Google Patents
Contact lensInfo
- Publication number
- CA1099546A CA1099546A CA289,638A CA289638A CA1099546A CA 1099546 A CA1099546 A CA 1099546A CA 289638 A CA289638 A CA 289638A CA 1099546 A CA1099546 A CA 1099546A
- Authority
- CA
- Canada
- Prior art keywords
- lens
- methacrylate
- curve
- varies
- hydrogel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000017 hydrogel Substances 0.000 claims abstract description 26
- 125000005250 alkyl acrylate group Chemical group 0.000 claims description 11
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims description 9
- 150000005690 diesters Chemical class 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 230000036571 hydration Effects 0.000 claims description 6
- 238000006703 hydration reaction Methods 0.000 claims description 6
- 239000000178 monomer Substances 0.000 claims description 5
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical group COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims description 4
- 230000004397 blinking Effects 0.000 claims description 4
- -1 dihydroxyalkyl acrylate Chemical compound 0.000 claims description 4
- 210000000744 eyelid Anatomy 0.000 claims description 4
- 230000009975 flexible effect Effects 0.000 claims description 4
- QRIMLDXJAPZHJE-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-methylprop-2-enoate Chemical group CC(=C)C(=O)OCC(O)CO QRIMLDXJAPZHJE-UHFFFAOYSA-N 0.000 claims description 2
- 239000003431 cross linking reagent Substances 0.000 claims description 2
- VOZRXNHHFUQHIL-UHFFFAOYSA-N glycidyl methacrylate Chemical group CC(=C)C(=O)OCC1CO1 VOZRXNHHFUQHIL-UHFFFAOYSA-N 0.000 claims description 2
- 229920001897 terpolymer Polymers 0.000 claims description 2
- 229940063557 methacrylate Drugs 0.000 claims 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 1
- DBCAQXHNJOFNGC-UHFFFAOYSA-N 4-bromo-1,1,1-trifluorobutane Chemical group FC(F)(F)CCCBr DBCAQXHNJOFNGC-UHFFFAOYSA-N 0.000 claims 1
- STVZJERGLQHEKB-UHFFFAOYSA-N ethylene glycol dimethacrylate Substances CC(=C)C(=O)OCCOC(=O)C(C)=C STVZJERGLQHEKB-UHFFFAOYSA-N 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract description 25
- 229910052760 oxygen Inorganic materials 0.000 abstract description 25
- 239000001301 oxygen Substances 0.000 abstract description 25
- 210000004087 cornea Anatomy 0.000 abstract description 10
- 230000006378 damage Effects 0.000 abstract description 6
- 238000009792 diffusion process Methods 0.000 abstract description 4
- 230000006835 compression Effects 0.000 abstract description 2
- 238000007906 compression Methods 0.000 abstract description 2
- 230000000694 effects Effects 0.000 abstract description 2
- 238000009736 wetting Methods 0.000 abstract description 2
- 210000001736 capillary Anatomy 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 6
- 230000002093 peripheral effect Effects 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 239000003054 catalyst Substances 0.000 description 4
- 230000001419 dependent effect Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 2
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 125000004990 dihydroxyalkyl group Chemical group 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 150000002734 metacrylic acid derivatives Chemical class 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- WWSNKXVETXETTP-UHFFFAOYSA-N 3,3-dihydroxyprop-2-enoic acid Chemical compound OC(O)=CC(O)=O WWSNKXVETXETTP-UHFFFAOYSA-N 0.000 description 1
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 238000012662 bulk polymerization Methods 0.000 description 1
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical compound CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000002844 continuous effect Effects 0.000 description 1
- 239000011243 crosslinked material Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- SUPCQIBBMFXVTL-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate Chemical compound CCOC(=O)C(C)=C SUPCQIBBMFXVTL-UHFFFAOYSA-N 0.000 description 1
- ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 125000005395 methacrylic acid group Chemical class 0.000 description 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- BWJUFXUULUEGMA-UHFFFAOYSA-N propan-2-yl propan-2-yloxycarbonyloxy carbonate Chemical group CC(C)OC(=O)OOC(=O)OC(C)C BWJUFXUULUEGMA-UHFFFAOYSA-N 0.000 description 1
- NHARPDSAXCBDDR-UHFFFAOYSA-N propyl 2-methylprop-2-enoate Chemical compound CCCOC(=O)C(C)=C NHARPDSAXCBDDR-UHFFFAOYSA-N 0.000 description 1
- 230000036647 reaction Effects 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Eyeglasses (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/736,555 US4180308A (en) | 1972-10-02 | 1976-10-28 | Contact lens |
US736,555 | 1976-10-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1099546A true CA1099546A (en) | 1981-04-21 |
Family
ID=24960333
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA289,638A Expired CA1099546A (en) | 1976-10-28 | 1977-10-27 | Contact lens |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS5383641A (enrdf_load_stackoverflow) |
CA (1) | CA1099546A (enrdf_load_stackoverflow) |
DE (1) | DE2748481A1 (enrdf_load_stackoverflow) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2564264A1 (en) | 2010-04-13 | 2013-03-06 | Johnson & Johnson Vision Care, Inc. | Contact lenses displaying reduced indoor glare |
US10816822B2 (en) | 2010-04-13 | 2020-10-27 | Johnson & Johnson Vision Care, Inc. | Pupil-only photochromic contact lenses displaying desirable optics and comfort |
US10894374B2 (en) | 2010-04-13 | 2021-01-19 | Johnson & Johnson Vision Care, Inc. | Process for manufacture of a thermochromic contact lens material |
US11724471B2 (en) | 2019-03-28 | 2023-08-15 | Johnson & Johnson Vision Care, Inc. | Methods for the manufacture of photoabsorbing contact lenses and photoabsorbing contact lenses produced thereby |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3002664C2 (de) * | 1980-01-25 | 1989-05-18 | Titmus Eurocon Kontaktlinsen Gmbh & Co Kg, 8750 Aschaffenburg | Weiche Kontaktlinse |
AU629725B2 (en) * | 1990-01-24 | 1992-10-08 | Novartis Ag | Contact lens and process for the manufacture thereof |
JPH06121414A (ja) * | 1992-10-07 | 1994-04-28 | Fanuc Ltd | 中継モジュール |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3220960A (en) * | 1960-12-21 | 1965-11-30 | Wichterle Otto | Cross-linked hydrophilic polymers and articles made therefrom |
US3957362A (en) * | 1972-10-02 | 1976-05-18 | Corneal Sciences, Inc. | Hydrogels and articles made therefrom |
US4056496A (en) * | 1972-10-02 | 1977-11-01 | Corneal Sciences, Inc. | Hydrogels and articles made therefrom |
-
1977
- 1977-10-27 CA CA289,638A patent/CA1099546A/en not_active Expired
- 1977-10-28 JP JP12955977A patent/JPS5383641A/ja active Granted
- 1977-10-28 DE DE19772748481 patent/DE2748481A1/de not_active Ceased
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2564264A1 (en) | 2010-04-13 | 2013-03-06 | Johnson & Johnson Vision Care, Inc. | Contact lenses displaying reduced indoor glare |
US9690115B2 (en) | 2010-04-13 | 2017-06-27 | Johnson & Johnson Vision Care, Inc. | Contact lenses displaying reduced indoor glare |
US10816822B2 (en) | 2010-04-13 | 2020-10-27 | Johnson & Johnson Vision Care, Inc. | Pupil-only photochromic contact lenses displaying desirable optics and comfort |
US10894374B2 (en) | 2010-04-13 | 2021-01-19 | Johnson & Johnson Vision Care, Inc. | Process for manufacture of a thermochromic contact lens material |
US11391965B2 (en) | 2010-04-13 | 2022-07-19 | Johnson & Johnson Vision Care, Inc. | Pupil-only photochromic contact lenses displaying desirable optics and comfort |
US11724472B2 (en) | 2010-04-13 | 2023-08-15 | Johnson & Johnson Vision Care, Inc. | Process for manufacture of a thermochromic contact lens material |
US11789291B2 (en) | 2010-04-13 | 2023-10-17 | Johnson & Johnson Vision Care, Inc. | Pupil-only photochromic contact lenses displaying desirable optics and comfort |
US11724471B2 (en) | 2019-03-28 | 2023-08-15 | Johnson & Johnson Vision Care, Inc. | Methods for the manufacture of photoabsorbing contact lenses and photoabsorbing contact lenses produced thereby |
US12128641B2 (en) | 2019-03-28 | 2024-10-29 | Johnson & Johnson Vision Care, Inc. | Methods for the manufacture of photoabsorbing contact lenses and photoabsorbing contact lenses produced thereby |
Also Published As
Publication number | Publication date |
---|---|
JPS5383641A (en) | 1978-07-24 |
JPS6227362B2 (enrdf_load_stackoverflow) | 1987-06-15 |
DE2748481A1 (de) | 1978-05-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |