CA1092601A - Derivatives of somatostatin - Google Patents

Derivatives of somatostatin

Info

Publication number
CA1092601A
CA1092601A CA247,515A CA247515A CA1092601A CA 1092601 A CA1092601 A CA 1092601A CA 247515 A CA247515 A CA 247515A CA 1092601 A CA1092601 A CA 1092601A
Authority
CA
Canada
Prior art keywords
phe
cys
gly
ala
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA247,515A
Other languages
English (en)
French (fr)
Inventor
Edmond Sandrin
Wilfried Bauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1092601A publication Critical patent/CA1092601A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA247,515A 1975-03-11 1976-03-10 Derivatives of somatostatin Expired CA1092601A (en)

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
CH3055/75 1975-03-11
CH305575 1975-03-11
CH3572/75 1975-03-20
CH357275 1975-03-20
CH10610/75 1975-08-14
CH1061075 1975-08-14
CH1228275 1975-09-22
CH12282/75 1975-09-22
CH1258675 1975-09-29
CH12586/75 1975-09-29
CH1511875 1975-11-21
CH1511775 1975-11-21
CH15117/75 1975-11-21
CH15119/75 1975-11-21
CH15118/75 1975-11-21
CH1511975 1975-11-21
CH15252/75 1975-11-25
CH1525275 1975-11-25

Publications (1)

Publication Number Publication Date
CA1092601A true CA1092601A (en) 1980-12-30

Family

ID=27575775

Family Applications (1)

Application Number Title Priority Date Filing Date
CA247,515A Expired CA1092601A (en) 1975-03-11 1976-03-10 Derivatives of somatostatin

Country Status (13)

Country Link
JP (1) JPS51115467A (no)
AU (1) AU509661B2 (no)
CA (1) CA1092601A (no)
DE (1) DE2608336A1 (no)
FI (1) FI760539A (no)
FR (1) FR2303560A1 (no)
GB (1) GB1546517A (no)
IE (1) IE44284B1 (no)
IL (1) IL49180A (no)
NL (1) NL7602395A (no)
NO (1) NO760707L (no)
NZ (1) NZ180247A (no)
PT (1) PT64881B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104267A (en) * 1977-02-22 1978-08-01 American Home Products Corporation Somatostatin analogs
GB1596329A (en) * 1977-04-21 1981-08-26 Lilly Co Eli Tetradeca peptides
US4100117A (en) * 1977-04-21 1978-07-11 Eli Lilly And Company Somatostatin analogs and intermediates thereto
US4118380A (en) * 1977-07-25 1978-10-03 Ayerst, Mckenna & Harrison Limited Decapeptide analogs of somatostatin
US4244947A (en) * 1979-08-13 1981-01-13 Ayerst Mckenna And Harrison Inc. Carba decapeptide derivatives of [TYR6 ]-somatostatin
DK81082A (da) * 1981-03-06 1982-09-07 Sandoz Ag Fremgangsmaade til fremstilling af polypeptider
JPS57183797A (en) * 1981-05-06 1982-11-12 Yamanouchi Pharmaceut Co Ltd Straight and purely short-chain peptide and its preparation
WO1983000364A1 (en) * 1981-07-17 1983-02-03 John Trevor Rice A motor-pump assembly
US4485101A (en) * 1983-10-11 1984-11-27 Administrators Of The Tulane Educational Fund Peptides
DK2465541T3 (en) 2007-05-22 2018-09-17 Wyeth Llc improved methods for producing hydrazides
SG11201406629VA (en) * 2012-04-16 2014-11-27 Allergan Inc (2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators

Also Published As

Publication number Publication date
NO760707L (no) 1976-09-14
NZ180247A (en) 1978-09-25
PT64881A (fr) 1976-04-01
IL49180A0 (en) 1976-05-31
IE44284L (en) 1976-09-11
FR2303560A1 (fr) 1976-10-08
AU1189376A (en) 1977-09-15
DE2608336A1 (de) 1976-09-30
JPS51115467A (en) 1976-10-12
FR2303560B1 (no) 1978-11-17
IL49180A (en) 1980-12-31
FI760539A (no) 1976-09-12
GB1546517A (en) 1979-05-23
AU509661B2 (en) 1980-05-22
IE44284B1 (en) 1981-10-07
NL7602395A (nl) 1976-09-14
PT64881B (fr) 1977-11-17

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Legal Events

Date Code Title Description
MKEX Expiry