CA1092601A - Derives de la somatostatine - Google Patents

Derives de la somatostatine

Info

Publication number
CA1092601A
CA1092601A CA247,515A CA247515A CA1092601A CA 1092601 A CA1092601 A CA 1092601A CA 247515 A CA247515 A CA 247515A CA 1092601 A CA1092601 A CA 1092601A
Authority
CA
Canada
Prior art keywords
phe
cys
gly
ala
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA247,515A
Other languages
English (en)
Inventor
Edmond Sandrin
Wilfried Bauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1092601A publication Critical patent/CA1092601A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA247,515A 1975-03-11 1976-03-10 Derives de la somatostatine Expired CA1092601A (fr)

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
CH305575 1975-03-11
CH3055/75 1975-03-11
CH357275 1975-03-20
CH3572/75 1975-03-20
CH10610/75 1975-08-14
CH1061075 1975-08-14
CH1228275 1975-09-22
CH12282/75 1975-09-22
CH12586/75 1975-09-29
CH1258675 1975-09-29
CH1511775 1975-11-21
CH15117/75 1975-11-21
CH15119/75 1975-11-21
CH15118/75 1975-11-21
CH1511975 1975-11-21
CH1511875 1975-11-21
CH15252/75 1975-11-25
CH1525275 1975-11-25

Publications (1)

Publication Number Publication Date
CA1092601A true CA1092601A (fr) 1980-12-30

Family

ID=27575775

Family Applications (1)

Application Number Title Priority Date Filing Date
CA247,515A Expired CA1092601A (fr) 1975-03-11 1976-03-10 Derives de la somatostatine

Country Status (13)

Country Link
JP (1) JPS51115467A (fr)
AU (1) AU509661B2 (fr)
CA (1) CA1092601A (fr)
DE (1) DE2608336A1 (fr)
FI (1) FI760539A (fr)
FR (1) FR2303560A1 (fr)
GB (1) GB1546517A (fr)
IE (1) IE44284B1 (fr)
IL (1) IL49180A (fr)
NL (1) NL7602395A (fr)
NO (1) NO760707L (fr)
NZ (1) NZ180247A (fr)
PT (1) PT64881B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104267A (en) * 1977-02-22 1978-08-01 American Home Products Corporation Somatostatin analogs
GB1596329A (en) * 1977-04-21 1981-08-26 Lilly Co Eli Tetradeca peptides
US4100117A (en) * 1977-04-21 1978-07-11 Eli Lilly And Company Somatostatin analogs and intermediates thereto
US4118380A (en) * 1977-07-25 1978-10-03 Ayerst, Mckenna & Harrison Limited Decapeptide analogs of somatostatin
US4244947A (en) * 1979-08-13 1981-01-13 Ayerst Mckenna And Harrison Inc. Carba decapeptide derivatives of [TYR6 ]-somatostatin
DK81082A (da) * 1981-03-06 1982-09-07 Sandoz Ag Fremgangsmaade til fremstilling af polypeptider
JPS57183797A (en) * 1981-05-06 1982-11-12 Yamanouchi Pharmaceut Co Ltd Straight and purely short-chain peptide and its preparation
EP0084540A4 (fr) * 1981-07-17 1985-04-24 John Trevor Rice Assemblage moteur-pompe.
US4485101A (en) * 1983-10-11 1984-11-27 Administrators Of The Tulane Educational Fund Peptides
CN101835494B (zh) 2007-05-22 2012-02-15 惠氏有限责任公司 制造酰肼的改良方法
SG11201406629VA (en) * 2012-04-16 2014-11-27 Allergan Inc (2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators

Also Published As

Publication number Publication date
GB1546517A (en) 1979-05-23
NZ180247A (en) 1978-09-25
AU509661B2 (en) 1980-05-22
DE2608336A1 (de) 1976-09-30
IE44284B1 (en) 1981-10-07
PT64881A (fr) 1976-04-01
FR2303560B1 (fr) 1978-11-17
IL49180A0 (en) 1976-05-31
IE44284L (en) 1976-09-11
FR2303560A1 (fr) 1976-10-08
IL49180A (en) 1980-12-31
NO760707L (fr) 1976-09-14
AU1189376A (en) 1977-09-15
FI760539A (fr) 1976-09-12
PT64881B (fr) 1977-11-17
NL7602395A (nl) 1976-09-14
JPS51115467A (en) 1976-10-12

Similar Documents

Publication Publication Date Title
US4291022A (en) Organic compounds
CA1148146A (fr) Cyclopeptides et preparations pharmaceutiques les contenant et aussi procede de preparation
US4603120A (en) Cyclic octapeptides and pharmaceutical preparations thereof, as well as processes for their manufacture, and their use
CA1092601A (fr) Derives de la somatostatine
US4261886A (en) Peptides having thymopoietin-like activity
JP2514518B2 (ja) ヘプタペプチドおよびオクタペプチドのソマトスタチン類似アミド誘導体、それを含有する抗腫瘍剤
CA1236451A (fr) Pentapeptides cycliques antagonistes de la somatostatine et methode de traitement des mammiferes a l'aide de cette substance
US4707468A (en) Polypeptide
JPS61293997A (ja) 生活性リジン含有オクタペプチド及びその調整方法
EP0187622A2 (fr) Dérivés de somatostatine
JPS59500863A (ja) ゴナドリベリン誘導体、その製造方法及びその医薬及び獣医薬組成物
US3853836A (en) Psychopharmacologically active peptides related to acth
CA1105006A (fr) Peptides
AU641366B2 (en) Peptide compounds
CA1066695A (fr) Analogues de la somatostatine et intermediaires
US4110322A (en) Peptide derivatives and pharmaceutical compositions containing same
NZ193077A (en) Peptides with ubiquitin-like activity; and pharmaceutical compositions
US3856770A (en) Psychopharmacologically active tetra-, penta-, hexa-, and heptapeptides
US3770715A (en) Acth active peptides having d serine as first aminoacid from n terminus and l ornithine as11 aminoacid
GB1578873A (en) Tetrapeptides and pentapeptides
HU185229B (en) Process for preparing pharmaceutically active peptides and acetates thereof
US4496543A (en) Polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use
US3803309A (en) Growth hormone release stimulating pharmaceutical preparations of n-acetyl-10-17 aminoacid acth-sequence peptides
CA1108124A (fr) Analogue de l'angiotensine ii antagoniste contenant un l-aminooxyacide en position i
US4203975A (en) Psychopharmacological peptides suitable for therapeutic administration

Legal Events

Date Code Title Description
MKEX Expiry