IE44284L - Polypeptides - Google Patents

Polypeptides

Info

Publication number
IE44284L
IE44284L IE760493A IE49376A IE44284L IE 44284 L IE44284 L IE 44284L IE 760493 A IE760493 A IE 760493A IE 49376 A IE49376 A IE 49376A IE 44284 L IE44284 L IE 44284L
Authority
IE
Ireland
Prior art keywords
polypeptides
ca1092601a
somatostatin
derivatives
bond
Prior art date
Application number
IE760493A
Other versions
IE44284B1 (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE44284L publication Critical patent/IE44284L/en
Publication of IE44284B1 publication Critical patent/IE44284B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Derivatives of Somatostatin This invention provides new compounds of formula I, I wherein R1, X, Y and Z are amino acid residues and each B is hydrogen or together are a bond, useful as growth hormone secretion inhibitors. [CA1092601A]
IE493/76A 1975-03-11 1976-03-09 Improvements in or relating to organic compounds IE44284B1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CH305575 1975-03-11
CH357275 1975-03-20
CH1061075 1975-08-14
CH1228275 1975-09-22
CH1258675 1975-09-29
CH1511875 1975-11-21
CH1511775 1975-11-21
CH1511975 1975-11-21
CH1525275 1975-11-25

Publications (2)

Publication Number Publication Date
IE44284L true IE44284L (en) 1976-09-11
IE44284B1 IE44284B1 (en) 1981-10-07

Family

ID=27575775

Family Applications (1)

Application Number Title Priority Date Filing Date
IE493/76A IE44284B1 (en) 1975-03-11 1976-03-09 Improvements in or relating to organic compounds

Country Status (13)

Country Link
JP (1) JPS51115467A (en)
AU (1) AU509661B2 (en)
CA (1) CA1092601A (en)
DE (1) DE2608336A1 (en)
FI (1) FI760539A (en)
FR (1) FR2303560A1 (en)
GB (1) GB1546517A (en)
IE (1) IE44284B1 (en)
IL (1) IL49180A (en)
NL (1) NL7602395A (en)
NO (1) NO760707L (en)
NZ (1) NZ180247A (en)
PT (1) PT64881B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104267A (en) * 1977-02-22 1978-08-01 American Home Products Corporation Somatostatin analogs
US4100117A (en) * 1977-04-21 1978-07-11 Eli Lilly And Company Somatostatin analogs and intermediates thereto
GB1596329A (en) * 1977-04-21 1981-08-26 Lilly Co Eli Tetradeca peptides
US4118380A (en) * 1977-07-25 1978-10-03 Ayerst, Mckenna & Harrison Limited Decapeptide analogs of somatostatin
US4244947A (en) * 1979-08-13 1981-01-13 Ayerst Mckenna And Harrison Inc. Carba decapeptide derivatives of [TYR6 ]-somatostatin
DK81082A (en) * 1981-03-06 1982-09-07 Sandoz Ag PROCEDURE FOR PREPARING POLYPEPTIDES
JPS57183797A (en) * 1981-05-06 1982-11-12 Yamanouchi Pharmaceut Co Ltd Straight and purely short-chain peptide and its preparation
EP0084540A4 (en) * 1981-07-17 1985-04-24 John Trevor Rice A motor-pump assembly.
US4485101A (en) * 1983-10-11 1984-11-27 Administrators Of The Tulane Educational Fund Peptides
MX2009012587A (en) 2007-05-22 2010-05-14 Wyeth Llc Improved processes for making hydrazides.
WO2013158597A1 (en) * 2012-04-16 2013-10-24 Allergan, Inc. (2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators

Also Published As

Publication number Publication date
NL7602395A (en) 1976-09-14
NZ180247A (en) 1978-09-25
FR2303560B1 (en) 1978-11-17
IE44284B1 (en) 1981-10-07
AU1189376A (en) 1977-09-15
NO760707L (en) 1976-09-14
IL49180A0 (en) 1976-05-31
PT64881B (en) 1977-11-17
CA1092601A (en) 1980-12-30
JPS51115467A (en) 1976-10-12
FR2303560A1 (en) 1976-10-08
DE2608336A1 (en) 1976-09-30
FI760539A (en) 1976-09-12
GB1546517A (en) 1979-05-23
PT64881A (en) 1976-04-01
IL49180A (en) 1980-12-31
AU509661B2 (en) 1980-05-22

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