CA1088520A - Process for the manufacture of dipeptide derivatives - Google Patents

Process for the manufacture of dipeptide derivatives

Info

Publication number
CA1088520A
CA1088520A CA274,078A CA274078A CA1088520A CA 1088520 A CA1088520 A CA 1088520A CA 274078 A CA274078 A CA 274078A CA 1088520 A CA1088520 A CA 1088520A
Authority
CA
Canada
Prior art keywords
formula
histidyl
proline
group
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA274,078A
Other languages
English (en)
French (fr)
Inventor
Eberhard Schwertner
Leopold A.N. Flohe
Siegfried Herrling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Application granted granted Critical
Publication of CA1088520A publication Critical patent/CA1088520A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
CA274,078A 1976-04-09 1977-03-16 Process for the manufacture of dipeptide derivatives Expired CA1088520A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2615455A DE2615455C2 (de) 1976-04-09 1976-04-09 N-Acyl-L-histidyl-L-prolin (N-substituierte)-amide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
DEP2615455.2 1976-04-09

Publications (1)

Publication Number Publication Date
CA1088520A true CA1088520A (en) 1980-10-28

Family

ID=5974903

Family Applications (1)

Application Number Title Priority Date Filing Date
CA274,078A Expired CA1088520A (en) 1976-04-09 1977-03-16 Process for the manufacture of dipeptide derivatives

Country Status (17)

Country Link
JP (1) JPS52125166A (sv)
AT (1) AT352921B (sv)
AU (1) AU2322677A (sv)
BE (1) BE853444A (sv)
CA (1) CA1088520A (sv)
CH (1) CH632737A5 (sv)
DE (1) DE2615455C2 (sv)
DK (1) DK148902C (sv)
ES (1) ES457563A1 (sv)
FR (1) FR2347338A1 (sv)
GB (1) GB1564078A (sv)
IE (1) IE44485B1 (sv)
NL (1) NL7703789A (sv)
PT (1) PT66283B (sv)
SE (1) SE427835B (sv)
YU (1) YU85977A (sv)
ZA (1) ZA771097B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58849B1 (en) * 1984-12-18 1993-11-17 Gruenenthal Chemie Use of dipeptide derivatives for the manufacture of medicaments for the treatment of patients with amyotrophic lateral sclerosis
DE3502041A1 (de) 1985-01-23 1986-07-24 Grünenthal GmbH, 5190 Stolberg Verwendung von dipeptidderivaten zur behandlung posttraumatischer nervenschaeden
JPS63316724A (ja) * 1987-06-19 1988-12-26 Nippon Shinyaku Co Ltd 抗けいれん剤
US5151497A (en) * 1989-02-21 1992-09-29 Japan Tobacco Inc. Histidyl peptide derivatives
WO1996008265A1 (en) * 1994-09-12 1996-03-21 The Trustees Of The University Of Pennsylvania Corticotropin release inhibiting factor and methods of using same
US6039956A (en) * 1994-09-12 2000-03-21 Pennsylvania, Trustees Of The University Of, The Corticotropin release inhibiting factor and methods of using same for treating behavioral symptoms in an anxiety disorder

Also Published As

Publication number Publication date
DK148902B (da) 1985-11-11
AU2322677A (en) 1978-09-21
DE2615455C2 (de) 1985-06-20
DK157077A (da) 1977-10-10
ATA113977A (de) 1979-03-15
AT352921B (de) 1979-10-10
DE2615455A1 (de) 1977-10-20
JPS6110479B2 (sv) 1986-03-29
FR2347338A1 (fr) 1977-11-04
IE44485B1 (en) 1981-12-16
GB1564078A (en) 1980-04-02
PT66283B (de) 1978-08-09
SE427835B (sv) 1983-05-09
JPS52125166A (en) 1977-10-20
PT66283A (de) 1977-04-01
DK148902C (da) 1986-06-09
ES457563A1 (es) 1978-03-16
BE853444A (fr) 1977-08-01
ZA771097B (en) 1978-01-25
IE44485L (en) 1977-10-09
NL7703789A (nl) 1977-10-11
FR2347338B1 (sv) 1980-07-11
SE7704088L (sv) 1977-10-10
YU85977A (en) 1982-10-31
CH632737A5 (en) 1982-10-29

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Legal Events

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