CA1088068A - Piperidino-quinazolines - Google Patents
Piperidino-quinazolinesInfo
- Publication number
- CA1088068A CA1088068A CA314,082A CA314082A CA1088068A CA 1088068 A CA1088068 A CA 1088068A CA 314082 A CA314082 A CA 314082A CA 1088068 A CA1088068 A CA 1088068A
- Authority
- CA
- Canada
- Prior art keywords
- formula
- lower alkyl
- piperidine
- alk
- chloroform
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB47583/77 | 1977-11-16 | ||
IE47583/77 | 1977-11-16 | ||
GB4758377 | 1977-11-16 | ||
GB7844533A GB2010824B (en) | 1977-11-16 | 1978-11-15 | Therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1088068A true CA1088068A (fr) | 1980-10-21 |
Family
ID=26266083
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA314,082A Expired CA1088068A (fr) | 1977-11-16 | 1978-10-24 | Piperidino-quinazolines |
Country Status (12)
Country | Link |
---|---|
JP (1) | JPS5481282A (fr) |
AT (1) | AT365183B (fr) |
AU (1) | AU509348B2 (fr) |
BE (1) | BE872023A (fr) |
CA (1) | CA1088068A (fr) |
CH (1) | CH637131A5 (fr) |
DE (1) | DE2849392A1 (fr) |
FR (1) | FR2409267A1 (fr) |
GB (1) | GB2010824B (fr) |
LU (1) | LU80531A1 (fr) |
NL (1) | NL174646C (fr) |
SE (1) | SE7811770L (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE800178L (en) * | 1979-01-31 | 1980-07-31 | Pfizer Ltd | Derivatives of 4-amino-2-piperidinoquinazoline |
FR2481278A1 (fr) * | 1980-04-28 | 1981-10-30 | Synthelabo | Nouveaux derives de piperidine, leur procede de preparation et leur application en therapeutique |
FR2514353A2 (fr) * | 1980-04-28 | 1983-04-15 | Synthelabo | Derives de piperidine et leur application en therapeutique |
JPS62212385A (ja) * | 1986-03-13 | 1987-09-18 | Kotobuki Seiyaku Kk | キナゾリン誘導体並びに血圧降下剤及びその製法 |
-
1978
- 1978-10-24 CA CA314,082A patent/CA1088068A/fr not_active Expired
- 1978-11-14 AU AU41576/78A patent/AU509348B2/en not_active Expired
- 1978-11-14 BE BE191743A patent/BE872023A/fr not_active IP Right Cessation
- 1978-11-14 DE DE19782849392 patent/DE2849392A1/de not_active Withdrawn
- 1978-11-14 SE SE7811770A patent/SE7811770L/xx unknown
- 1978-11-14 NL NLAANVRAGE7811236,A patent/NL174646C/xx not_active IP Right Cessation
- 1978-11-15 GB GB7844533A patent/GB2010824B/en not_active Expired
- 1978-11-15 CH CH1175578A patent/CH637131A5/de not_active IP Right Cessation
- 1978-11-15 FR FR7832235A patent/FR2409267A1/fr active Granted
- 1978-11-15 LU LU80531A patent/LU80531A1/fr unknown
- 1978-11-15 AT AT0816678A patent/AT365183B/de active
- 1978-11-15 JP JP14094678A patent/JPS5481282A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
SE7811770L (sv) | 1979-05-17 |
JPS5623991B2 (fr) | 1981-06-03 |
FR2409267B1 (fr) | 1981-02-27 |
LU80531A1 (fr) | 1980-06-05 |
AU509348B2 (en) | 1980-05-08 |
FR2409267A1 (fr) | 1979-06-15 |
DE2849392A1 (de) | 1979-05-23 |
GB2010824A (en) | 1979-07-04 |
CH637131A5 (de) | 1983-07-15 |
AT365183B (de) | 1981-12-28 |
AU4157678A (en) | 1979-05-24 |
GB2010824B (en) | 1982-06-16 |
NL174646C (nl) | 1984-07-16 |
NL174646B (nl) | 1984-02-16 |
ATA816678A (de) | 1981-05-15 |
JPS5481282A (en) | 1979-06-28 |
BE872023A (fr) | 1979-05-14 |
NL7811236A (nl) | 1979-05-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0100200B1 (fr) | Amino-4 diméthoxy-6,7 quinoléines substituées en position 2 | |
US4207324A (en) | 1,2-Di-Substituted-4-haloimidazole-5-acetic acid derivatives and their use | |
US5955495A (en) | Method of treating diseases of the CNS | |
JPS63119469A (ja) | 糖尿病合併症用組成物 | |
JPS6289679A (ja) | ピペリジン誘導体 | |
US4338323A (en) | Piperidylbenzimidazolinone derivatives | |
US4264613A (en) | Piperidylbenzimidazolinone compounds | |
CA1088068A (fr) | Piperidino-quinazolines | |
JPS63290868A (ja) | ジケトピペラジン誘導体およびその塩類 | |
EP0351435B1 (fr) | Composes de pyridazine fusionnes et leurs utilisations medicales | |
KR910003116B1 (ko) | 치환된 1h-이미다졸 | |
US4463001A (en) | 6-Substituted 6H-dibenzo[b,d]pyran derivatives and process for their preparation | |
US4442102A (en) | 1,5-Diphenylpyrazolin-3-one compounds, process and intermediates for preparation thereof and pharmaceutical compositions containing same | |
US4766137A (en) | 4-(isoxazolyl)-thiazole-2-oxamic acids and derivatives thereof | |
US4053600A (en) | Tricyclic 1,2,4-triazolo-quinazolines | |
GB2171997A (en) | 4-Amino-6,7-dimethoxy-2-Piperazin-1-ylquinazoline derivatives | |
DK158944B (da) | Analogifremgangsmaade til fremstilling af substituerede methylimidazolforbindelser | |
US4929616A (en) | Novel basic-substituted 5-halo-thienoisothiazol-3(2H)-one 1,1-dioxides, a process for the preparation thereof, and pharmaceutical preparations containing these compounds | |
US4479952A (en) | Monosubstituted piperazines | |
US4237138A (en) | Antihypertensive 4-amino-2-[4-(substituted-alkoxy)piperidino)]quinazolines | |
CA1131636A (fr) | Quinazoline utilisee contre l'hypertension | |
HU199813B (en) | Process for producing new benzothiazinone derivatives and pharmaceutical compositions comprising such active ingredient | |
FI74470B (fi) | Foerfarande foer framstaellning av 5-pyridyletenylderivat av 1h-pyrazolo/1,5-a/pyrimidiner. | |
DE3526044A1 (de) | Dihydrochinolinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung, sowie zwischenprodukte zu ihrer herstellung | |
IE47510B1 (en) | 4-amino-6,7-dialkoxy-2-substituted quinazolines |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |