CA1085854A - Cis-4a-phenylisoquinolines - Google Patents

Cis-4a-phenylisoquinolines

Info

Publication number
CA1085854A
CA1085854A CA267,852A CA267852A CA1085854A CA 1085854 A CA1085854 A CA 1085854A CA 267852 A CA267852 A CA 267852A CA 1085854 A CA1085854 A CA 1085854A
Authority
CA
Canada
Prior art keywords
compound
formula
hydrogen
carbon atoms
defined above
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA267,852A
Other languages
English (en)
Inventor
Paul Pfaffli
Hartmut Hauth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1628375A external-priority patent/CH619937A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1085854A publication Critical patent/CA1085854A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CA267,852A 1975-12-16 1976-12-14 Cis-4a-phenylisoquinolines Expired CA1085854A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH1628475 1975-12-16
CH16284/75 1975-12-16
CH1628375A CH619937A5 (en) 1975-12-16 1975-12-16 Process for the preparation of novel cis-4a-phenyl- isoquinolines
CH16283/75 1975-12-16

Publications (1)

Publication Number Publication Date
CA1085854A true CA1085854A (fr) 1980-09-16

Family

ID=25717645

Family Applications (1)

Application Number Title Priority Date Filing Date
CA267,852A Expired CA1085854A (fr) 1975-12-16 1976-12-14 Cis-4a-phenylisoquinolines

Country Status (10)

Country Link
JP (1) JPS5273881A (fr)
AU (1) AU512799B2 (fr)
CA (1) CA1085854A (fr)
DE (1) DE2655150A1 (fr)
FR (1) FR2335225A1 (fr)
GB (1) GB1568976A (fr)
IE (1) IE44403B1 (fr)
IL (1) IL51104A (fr)
NZ (1) NZ182883A (fr)
PH (1) PH13335A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2907461A1 (de) * 1978-03-10 1979-09-20 Sandoz Ag Isochinolinderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen
WO1997043263A1 (fr) * 1995-11-17 1997-11-20 Toray Industries, Inc. PROCEDE DE PRODUCTION DE DERIVES DE 4a-ARYLDECAHYDROISOQUINOLINE
AU6470996A (en) * 1995-07-20 1997-02-18 Toray Industries, Inc. 4a-aryldecahydroisoquinoline compounds and medicinal uses thereof
CN105473554B (zh) 2013-07-10 2019-08-13 沃泰克斯药物股份有限公司 作为离子通道调节剂的稠合的哌啶酰胺类

Also Published As

Publication number Publication date
IL51104A0 (en) 1977-02-28
AU512799B2 (en) 1980-10-30
PH13335A (en) 1980-03-13
IE44403L (en) 1977-06-16
AU2062576A (en) 1978-06-22
FR2335225B1 (fr) 1980-04-18
FR2335225A1 (fr) 1977-07-15
JPS5273881A (en) 1977-06-21
DE2655150A1 (de) 1977-06-23
NZ182883A (en) 1979-06-08
IE44403B1 (en) 1981-11-18
GB1568976A (en) 1980-06-11
IL51104A (en) 1981-12-31

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Legal Events

Date Code Title Description
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