CA1070688A - Analogues des cephalosporines - Google Patents

Analogues des cephalosporines

Info

Publication number
CA1070688A
CA1070688A CA265,376A CA265376A CA1070688A CA 1070688 A CA1070688 A CA 1070688A CA 265376 A CA265376 A CA 265376A CA 1070688 A CA1070688 A CA 1070688A
Authority
CA
Canada
Prior art keywords
compound
formula
prepared
hydrogen
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA265,376A
Other languages
English (en)
Inventor
Mitsuru Yoshioka
Hiroshi Onoue
Teruji Tsuji
Yasuhiro Nishitani
Masayuki Narisada
Yoshio Hamashima
Wataru Nagata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB4675975A external-priority patent/GB1569254A/en
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of CA1070688A publication Critical patent/CA1070688A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA265,376A 1975-11-12 1976-11-10 Analogues des cephalosporines Expired CA1070688A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4675975A GB1569254A (en) 1975-11-12 1975-11-12 Preparation of a-(2 -acetonyloxy-4-oxo-azetidin-1-yl) glycolic acids and derivatives thereof and their use in preparing oxacephalosporins
GB4989175 1975-12-04

Publications (1)

Publication Number Publication Date
CA1070688A true CA1070688A (fr) 1980-01-29

Family

ID=26265894

Family Applications (1)

Application Number Title Priority Date Filing Date
CA265,376A Expired CA1070688A (fr) 1975-11-12 1976-11-10 Analogues des cephalosporines

Country Status (7)

Country Link
JP (1) JPS5265292A (fr)
AU (1) AU502797B2 (fr)
CA (1) CA1070688A (fr)
CH (1) CH636617A5 (fr)
DE (1) DE2651771A1 (fr)
FR (1) FR2361114A1 (fr)
NL (1) NL7612638A (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180571A (en) * 1976-03-25 1979-12-25 Shionogi & Co., Ltd. Arylmalonamido-1-oxadethiacephalosporins
JPS607635B2 (ja) * 1976-04-27 1985-02-26 塩野義製薬株式会社 オキサゾリジン化合物
IE45650B1 (en) * 1976-08-09 1982-10-20 Shionogi & Co Intermediates for cephalosporin analogues
AU514377B2 (en) * 1977-02-15 1981-02-05 Shionogi & Co., Ltd. l-OXADETHIACEPHAM COMPOUNDS
JPS5419990A (en) * 1977-07-14 1979-02-15 Shionogi & Co Ltd Dihydrotriazinylthioxacephalosporin
JPS609718B2 (ja) * 1977-08-25 1985-03-12 塩野義製薬株式会社 チアジアゾリルチオセフアロスポリン類縁抗生物質
IT1102408B (it) * 1977-12-23 1985-10-07 Fujisawa Pharmaceutical Co Composti analoghi della cefalosforina e procedimenti per la loro preparazione
DE3225269A1 (de) * 1982-07-06 1984-01-12 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 7-amino-1-dethia-1-oxa-3-hydroxymethyl-cephem-4-carbonsaeuren

Also Published As

Publication number Publication date
NL7612638A (nl) 1977-05-16
AU1959876A (en) 1978-05-18
JPS5265292A (en) 1977-05-30
CH636617A5 (en) 1983-06-15
DE2651771A1 (de) 1977-05-26
FR2361114B1 (fr) 1982-09-17
AU502797B2 (en) 1979-08-09
FR2361114A1 (fr) 1978-03-10

Similar Documents

Publication Publication Date Title
CA1077936A (fr) Cyclisation conduisant a la formation de noyaux cepheme et d'intermediaires
CA1068259A (fr) Procede de cyclisation conduisant a des noyaux cephem
CA1059988A (fr) Procede pour la fabrication de derives enol
US4110533A (en) Process for the manufacture of enol derivatives
CA1070688A (fr) Analogues des cephalosporines
US4322347A (en) 2-Carbamoyloxymethyl-penicillin derivatives
CA1109859A (fr) Derives de thiooxime de cephalosporine et de penicilline
US4420426A (en) 6-Alpha-halopenicillanic acid 1,1-dioxides
US4122086A (en) Isopenicillins
KR840000589B1 (ko) 6-β-치환된 페니실란산의 제조방법
IE43845B1 (en) 4-thia-1-azabicyclo/4.2.0/oct-2-ene derivatives
US4166816A (en) Methods and intermediates for preparing cis-4-oxoazetidine intermediates
CH636100A5 (de) Dihydrotriazinylthiooxacephalosporine.
US4143038A (en) Cephalosporin analogues
US4072674A (en) Cis-4-oxoazetidine intermediates and methods of preparing them
US4310459A (en) Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters
US4550162A (en) Process for the manufacture of enol derivatives
US4614797A (en) Cephalosporin hydroxamic acids
GB1569254A (en) Preparation of a-(2 -acetonyloxy-4-oxo-azetidin-1-yl) glycolic acids and derivatives thereof and their use in preparing oxacephalosporins
US4374982A (en) Cepham compounds
US4434287A (en) Cephalosporin derivatives
US4257947A (en) 3-Amino-2-hydroxy, halo or mercaptomethyl-4-oxoazetidines
US4518773A (en) "3-Carbamoyloxy cephalosporins"
US4426520A (en) 3-Carbamoyloxy-cepham-4-carboxylic acid derivatives
US4182868A (en) 7-Methoxycephalosporin derivatives

Legal Events

Date Code Title Description
MKEX Expiry