CA1070315A - Process for the preparation of bis(heteroarylmethylthioethylguanidino) alkanes and the bis(heteroarylmethylthioethylguanidino) alkanes so formed - Google Patents
Process for the preparation of bis(heteroarylmethylthioethylguanidino) alkanes and the bis(heteroarylmethylthioethylguanidino) alkanes so formedInfo
- Publication number
- CA1070315A CA1070315A CA283,619A CA283619A CA1070315A CA 1070315 A CA1070315 A CA 1070315A CA 283619 A CA283619 A CA 283619A CA 1070315 A CA1070315 A CA 1070315A
- Authority
- CA
- Canada
- Prior art keywords
- compound
- methyl
- ethyl
- formula
- guanidino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/26—Radicals substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3139176 | 1976-07-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1070315A true CA1070315A (en) | 1980-01-22 |
Family
ID=10322405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA283,619A Expired CA1070315A (en) | 1976-07-28 | 1977-07-27 | Process for the preparation of bis(heteroarylmethylthioethylguanidino) alkanes and the bis(heteroarylmethylthioethylguanidino) alkanes so formed |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS5315370A (pl) |
| AU (1) | AU2734677A (pl) |
| BE (1) | BE857218A (pl) |
| CA (1) | CA1070315A (pl) |
| DE (1) | DE2733953A1 (pl) |
| DK (1) | DK331877A (pl) |
| ES (1) | ES461100A2 (pl) |
| FI (1) | FI772293A (pl) |
| FR (1) | FR2359840A1 (pl) |
| IL (1) | IL52544A0 (pl) |
| LU (1) | LU77845A1 (pl) |
| NL (1) | NL7708375A (pl) |
| NO (1) | NO772668L (pl) |
| PL (1) | PL107847B1 (pl) |
| ZA (1) | ZA774552B (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4309435A (en) | 1978-10-16 | 1982-01-05 | Imperial Chemical Industries Ltd. | Antisecretory guanidine derivatives and pharmaceutical compositions containing them |
| FR2446829A1 (fr) | 1978-11-16 | 1980-08-14 | Glaxo Group Ltd | Derives de polymethylene disubstitues en alpha, omega, procede pour leur preparation et compositions pharmaceutiques les contenant |
| JPS57102852A (en) * | 1980-12-19 | 1982-06-26 | Shionogi & Co Ltd | Dicarboxylic acid diamide |
| EP4196793A1 (en) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
-
1977
- 1977-07-18 IL IL52544A patent/IL52544A0/xx unknown
- 1977-07-22 DK DK331877A patent/DK331877A/da not_active Application Discontinuation
- 1977-07-26 AU AU27346/77A patent/AU2734677A/en active Pending
- 1977-07-26 LU LU77845A patent/LU77845A1/xx unknown
- 1977-07-27 FR FR7723079A patent/FR2359840A1/fr not_active Withdrawn
- 1977-07-27 BE BE179687A patent/BE857218A/xx unknown
- 1977-07-27 ZA ZA00774552A patent/ZA774552B/xx unknown
- 1977-07-27 NO NO772668A patent/NO772668L/no unknown
- 1977-07-27 CA CA283,619A patent/CA1070315A/en not_active Expired
- 1977-07-27 FI FI772293A patent/FI772293A/fi not_active Application Discontinuation
- 1977-07-27 DE DE19772733953 patent/DE2733953A1/de not_active Withdrawn
- 1977-07-28 PL PL1977199908A patent/PL107847B1/pl unknown
- 1977-07-28 NL NL7708375A patent/NL7708375A/xx not_active Application Discontinuation
- 1977-07-28 ES ES461100A patent/ES461100A2/es not_active Expired
- 1977-07-28 JP JP9132477A patent/JPS5315370A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| LU77845A1 (pl) | 1977-10-25 |
| JPS5315370A (en) | 1978-02-13 |
| DK331877A (da) | 1978-01-29 |
| PL199908A1 (pl) | 1978-11-20 |
| NO772668L (no) | 1978-01-31 |
| FR2359840A1 (fr) | 1978-02-24 |
| NL7708375A (nl) | 1978-01-31 |
| IL52544A0 (en) | 1977-10-31 |
| ZA774552B (en) | 1978-06-28 |
| DE2733953A1 (de) | 1978-02-02 |
| ES461100A2 (es) | 1978-12-01 |
| PL107847B1 (pl) | 1980-03-31 |
| BE857218A (fr) | 1978-01-27 |
| AU2734677A (en) | 1979-02-01 |
| FI772293A (pl) | 1978-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |