CA1065329A - Chromone derivatives - Google Patents

Chromone derivatives

Info

Publication number
CA1065329A
CA1065329A CA240,751A CA240751A CA1065329A CA 1065329 A CA1065329 A CA 1065329A CA 240751 A CA240751 A CA 240751A CA 1065329 A CA1065329 A CA 1065329A
Authority
CA
Canada
Prior art keywords
alkyl
formula
compound
hydroxy
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA240,751A
Other languages
English (en)
French (fr)
Inventor
Richard Hazard
John Mann
Roger C. Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB51944/74A external-priority patent/GB1517153A/en
Application filed by Fisons Ltd filed Critical Fisons Ltd
Application granted granted Critical
Publication of CA1065329A publication Critical patent/CA1065329A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA240,751A 1974-11-30 1975-11-27 Chromone derivatives Expired CA1065329A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB51944/74A GB1517153A (en) 1974-11-30 1974-11-30 Naphthopyran-and benzodipyran-2-carboxylic acids and derivatives thereof
GB5370474 1974-12-12
GB2104475 1975-05-16
GB2104375 1975-05-16

Publications (1)

Publication Number Publication Date
CA1065329A true CA1065329A (en) 1979-10-30

Family

ID=27448513

Family Applications (1)

Application Number Title Priority Date Filing Date
CA240,751A Expired CA1065329A (en) 1974-11-30 1975-11-27 Chromone derivatives

Country Status (23)

Country Link
US (1) US4238606A (d)
JP (1) JPS5176277A (d)
AR (2) AR215120A1 (d)
AT (1) AT351530B (d)
BR (1) BR7507936A (d)
CA (1) CA1065329A (d)
CH (2) CH615171A5 (d)
DD (1) DD124735A5 (d)
DE (1) DE2553688A1 (d)
DK (1) DK535175A (d)
ES (1) ES443093A1 (d)
FI (1) FI753369A7 (d)
FR (1) FR2292468A1 (d)
HU (1) HU175915B (d)
IE (1) IE42068B1 (d)
IL (2) IL48566A0 (d)
IT (1) IT1059533B (d)
MX (1) MX3391E (d)
NL (1) NL7513918A (d)
NO (1) NO145982C (d)
NZ (1) NZ179392A (d)
SE (1) SE420835B (d)
ZM (1) ZM16775A1 (d)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570993A (en) * 1976-05-21 1980-07-09 Fisons Ltd Pharmaceutical tablet formulation
AU522209B2 (en) * 1977-05-06 1982-05-20 Fisons Limited Veterinary use of cromoglycate-i. ike compounds
JPS5424895A (en) * 1977-07-28 1979-02-24 Eisai Co Ltd Pyranochromone derivatives and remedies for allergic disorder
US4269854A (en) * 1978-09-12 1981-05-26 Fisons Limited 6,7,8,9-Tetrahydro-4H-naphtho-[2,3-b]pyran-2-carboxylic acids

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1023373A (en) * 1962-03-07 1966-03-23 Benger Lab Ltd Chromone derivatives
GB1029213A (en) * 1966-04-02 1966-05-11 Benger Lab Ltd Chromone derivatives
US3291811A (en) * 1962-03-30 1966-12-13 Benger Lab Ltd Cyclohexano [g] chromones substituted in 2-position by carboxyl or carboxymethyl-aminocarbonyl
GB1024645A (en) * 1962-07-10 1966-03-30 Benger Lab Ltd Chromone compounds
GB1049289A (en) * 1962-08-18 1966-11-23 Benger Lab Ltd Chromone derivatives and pharmaceutical compositions containing them
GB1116562A (en) * 1964-09-05 1968-06-06 Fisons Pharmaceuticals Ltd A pyranochromone carboxylic acid and derivatives
FR1481033A (fr) * 1964-09-25 1967-05-19 Fisons Pharmaceuticals Ltd Procédé de préparation d'un nouveau dérivé de la chromone
GB1147976A (en) * 1965-12-21 1969-04-10 Fisons Pharmaceuticals Ltd Chromone derivatives
GB1223690A (en) * 1967-10-17 1971-03-03 Fisons Pharmaceuticals Ltd Substituted chromon-2-carboxylic acids
GB1291864A (en) * 1969-02-12 1972-10-04 Fisons Pharmaceuticals Ltd Mono thiachromone-2-carboxylic acids
GB1389227A (en) * 1971-09-16 1975-04-03 Fisons Ltd Chromone-2-carboxylic acid derivatives methods for their preparation and compositions containing them

Also Published As

Publication number Publication date
NZ179392A (en) 1978-04-03
NO145982B (no) 1982-03-29
DD124735A5 (d) 1977-03-09
CH618977A5 (d) 1980-08-29
IT1059533B (it) 1982-06-21
FI753369A7 (d) 1976-05-31
NL7513918A (nl) 1976-06-01
ES443093A1 (es) 1977-10-16
BR7507936A (pt) 1976-08-31
SE7513446L (sv) 1976-05-31
US4238606A (en) 1980-12-09
AT351530B (de) 1979-07-25
IL48566A0 (en) 1976-01-30
SE420835B (sv) 1981-11-02
HU175915B (en) 1980-11-28
NO145982C (no) 1982-07-07
AR215120A1 (es) 1979-09-14
ATA900675A (de) 1979-01-15
FR2292468A1 (fr) 1976-06-25
DE2553688A1 (de) 1976-06-10
MX3391E (es) 1980-10-27
ZM16775A1 (en) 1976-11-22
IL60824A0 (en) 1980-10-26
NO754040L (d) 1976-06-01
DK535175A (da) 1976-05-31
IE42068L (en) 1976-05-30
CH615171A5 (d) 1980-01-15
FR2292468B1 (d) 1978-12-01
IE42068B1 (en) 1980-05-21
JPS5176277A (d) 1976-07-01
AR219058A1 (es) 1980-07-31

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