NO145982C - Analogifremgangsmaate til fremstilling av terapeutisk virksomme monokromon-forbindelser - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk virksomme monokromon-forbindelser

Info

Publication number
NO145982C
NO145982C NO754040A NO754040A NO145982C NO 145982 C NO145982 C NO 145982C NO 754040 A NO754040 A NO 754040A NO 754040 A NO754040 A NO 754040A NO 145982 C NO145982 C NO 145982C
Authority
NO
Norway
Prior art keywords
monocromon
compounds
preparation
therapeutically effective
analogy procedure
Prior art date
Application number
NO754040A
Other languages
English (en)
Other versions
NO754040L (no
NO145982B (no
Inventor
Roger Charles Brown
Richard Hazard
John Mann
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB51944/74A external-priority patent/GB1517153A/en
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of NO754040L publication Critical patent/NO754040L/no
Publication of NO145982B publication Critical patent/NO145982B/no
Publication of NO145982C publication Critical patent/NO145982C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
NO754040A 1974-11-30 1975-12-01 Analogifremgangsmaate til fremstilling av terapeutisk virksomme monokromon-forbindelser NO145982C (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB51944/74A GB1517153A (en) 1974-11-30 1974-11-30 Naphthopyran-and benzodipyran-2-carboxylic acids and derivatives thereof
GB5370474 1974-12-12
GB2104375 1975-05-16
GB2104475 1975-05-16

Publications (3)

Publication Number Publication Date
NO754040L NO754040L (no) 1976-06-01
NO145982B NO145982B (no) 1982-03-29
NO145982C true NO145982C (no) 1982-07-07

Family

ID=27448513

Family Applications (1)

Application Number Title Priority Date Filing Date
NO754040A NO145982C (no) 1974-11-30 1975-12-01 Analogifremgangsmaate til fremstilling av terapeutisk virksomme monokromon-forbindelser

Country Status (23)

Country Link
US (1) US4238606A (no)
JP (1) JPS5176277A (no)
AR (2) AR215120A1 (no)
AT (1) AT351530B (no)
BR (1) BR7507936A (no)
CA (1) CA1065329A (no)
CH (2) CH615171A5 (no)
DD (1) DD124735A5 (no)
DE (1) DE2553688A1 (no)
DK (1) DK535175A (no)
ES (1) ES443093A1 (no)
FI (1) FI753369A (no)
FR (1) FR2292468A1 (no)
HU (1) HU175915B (no)
IE (1) IE42068B1 (no)
IL (2) IL48566A0 (no)
IT (1) IT1059533B (no)
MX (1) MX3391E (no)
NL (1) NL7513918A (no)
NO (1) NO145982C (no)
NZ (1) NZ179392A (no)
SE (1) SE420835B (no)
ZM (1) ZM16775A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570993A (en) * 1976-05-21 1980-07-09 Fisons Ltd Pharmaceutical tablet formulation
IE46952B1 (en) * 1977-05-06 1983-11-16 Fisons Ltd Method of treating animals
JPS5424895A (en) * 1977-07-28 1979-02-24 Eisai Co Ltd Pyranochromone derivatives and remedies for allergic disorder
US4269854A (en) * 1978-09-12 1981-05-26 Fisons Limited 6,7,8,9-Tetrahydro-4H-naphtho-[2,3-b]pyran-2-carboxylic acids

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1023373A (en) * 1962-03-07 1966-03-23 Benger Lab Ltd Chromone derivatives
GB1029213A (en) * 1966-04-02 1966-05-11 Benger Lab Ltd Chromone derivatives
US3291811A (en) * 1962-03-30 1966-12-13 Benger Lab Ltd Cyclohexano [g] chromones substituted in 2-position by carboxyl or carboxymethyl-aminocarbonyl
GB1024645A (en) * 1962-07-10 1966-03-30 Benger Lab Ltd Chromone compounds
GB1049289A (en) * 1962-08-18 1966-11-23 Benger Lab Ltd Chromone derivatives and pharmaceutical compositions containing them
GB1116562A (en) * 1964-09-05 1968-06-06 Fisons Pharmaceuticals Ltd A pyranochromone carboxylic acid and derivatives
FR1481033A (fr) * 1964-09-25 1967-05-19 Fisons Pharmaceuticals Ltd Procédé de préparation d'un nouveau dérivé de la chromone
GB1147976A (en) * 1965-12-21 1969-04-10 Fisons Pharmaceuticals Ltd Chromone derivatives
GB1223690A (en) * 1967-10-17 1971-03-03 Fisons Pharmaceuticals Ltd Substituted chromon-2-carboxylic acids
GB1291864A (en) * 1969-02-12 1972-10-04 Fisons Pharmaceuticals Ltd Mono thiachromone-2-carboxylic acids
GB1389227A (en) * 1971-09-16 1975-04-03 Fisons Ltd Chromone-2-carboxylic acid derivatives methods for their preparation and compositions containing them

Also Published As

Publication number Publication date
ZM16775A1 (en) 1976-11-22
AR219058A1 (es) 1980-07-31
NZ179392A (en) 1978-04-03
MX3391E (es) 1980-10-27
FI753369A (no) 1976-05-31
BR7507936A (pt) 1976-08-31
DK535175A (da) 1976-05-31
HU175915B (en) 1980-11-28
IL60824A0 (en) 1980-10-26
ES443093A1 (es) 1977-10-16
NO754040L (no) 1976-06-01
JPS5176277A (no) 1976-07-01
ATA900675A (de) 1979-01-15
DE2553688A1 (de) 1976-06-10
FR2292468A1 (fr) 1976-06-25
SE420835B (sv) 1981-11-02
NL7513918A (nl) 1976-06-01
IE42068B1 (en) 1980-05-21
FR2292468B1 (no) 1978-12-01
IE42068L (en) 1976-05-30
IL48566A0 (en) 1976-01-30
SE7513446L (sv) 1976-05-31
CA1065329A (en) 1979-10-30
AT351530B (de) 1979-07-25
AR215120A1 (es) 1979-09-14
DD124735A5 (no) 1977-03-09
NO145982B (no) 1982-03-29
CH618977A5 (no) 1980-08-29
US4238606A (en) 1980-12-09
CH615171A5 (no) 1980-01-15
IT1059533B (it) 1982-06-21

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