CA1064029A - 2-substituted thio-1,4-benzodiazepine derivatives - Google Patents

2-substituted thio-1,4-benzodiazepine derivatives

Info

Publication number
CA1064029A
CA1064029A CA222,537A CA222537A CA1064029A CA 1064029 A CA1064029 A CA 1064029A CA 222537 A CA222537 A CA 222537A CA 1064029 A CA1064029 A CA 1064029A
Authority
CA
Canada
Prior art keywords
chloro
benzodiazepine
chlorophenyl
give
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA222,537A
Other languages
English (en)
French (fr)
Inventor
Ikuo Ueda
Masaaki Matsuo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA1064029A publication Critical patent/CA1064029A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/22—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA222,537A 1974-03-20 1975-03-19 2-substituted thio-1,4-benzodiazepine derivatives Expired CA1064029A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49031905A JPS5919099B2 (ja) 1974-03-20 1974-03-20 ２−置換チオ−１，４−ベンゾジアゼピン誘導体の製造法

Publications (1)

Publication Number Publication Date
CA1064029A true CA1064029A (en) 1979-10-09

Family

ID=12344003

Family Applications (1)

Application Number Title Priority Date Filing Date
CA222,537A Expired CA1064029A (en) 1974-03-20 1975-03-19 2-substituted thio-1,4-benzodiazepine derivatives

Country Status (15)

Country Link
JP (1) JPS5919099B2 (enExample)
AU (1) AU7929875A (enExample)
BE (1) BE826817A (enExample)
CA (1) CA1064029A (enExample)
DE (1) DE2511898A1 (enExample)
DK (1) DK114175A (enExample)
ES (1) ES435812A1 (enExample)
FI (1) FI750816A7 (enExample)
FR (1) FR2264545B1 (enExample)
GB (1) GB1467763A (enExample)
HU (1) HU170141B (enExample)
NL (1) NL7503269A (enExample)
NO (1) NO750943L (enExample)
SE (1) SE7503164L (enExample)
ZA (1) ZA751715B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4094870A (en) * 1974-03-20 1978-06-13 Fujisawa Pharmaceutical Co., Ltd. 2-Substituted thio-1,4-benzodiazepine derivatives
HU224435B1 (hu) * 1995-02-09 2005-10-28 EGIS Gyógyszergyár Rt. Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények

Also Published As

Publication number Publication date
BE826817A (fr) 1975-09-18
NL7503269A (nl) 1975-09-23
DK114175A (enExample) 1975-09-21
JPS5919099B2 (ja) 1984-05-02
HU170141B (enExample) 1977-04-28
DE2511898A1 (de) 1975-09-25
AU7929875A (en) 1976-09-23
SE7503164L (enExample) 1975-09-22
NO750943L (enExample) 1975-09-23
FI750816A7 (enExample) 1975-09-21
GB1467763A (en) 1977-03-23
JPS50131980A (enExample) 1975-10-18
ZA751715B (en) 1976-02-25
ES435812A1 (es) 1976-12-01
FR2264545B1 (enExample) 1978-08-04
FR2264545A1 (enExample) 1975-10-17

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