CA1062616A - Analgetic composition containing an indole-3-acetic acid derivative - Google Patents

Analgetic composition containing an indole-3-acetic acid derivative

Info

Publication number
CA1062616A
CA1062616A CA253,859A CA253859A CA1062616A CA 1062616 A CA1062616 A CA 1062616A CA 253859 A CA253859 A CA 253859A CA 1062616 A CA1062616 A CA 1062616A
Authority
CA
Canada
Prior art keywords
acetic acid
methyl
analgetic
compound
hexahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA253,859A
Other languages
English (en)
French (fr)
Inventor
Toshiya Inukai
Hisao Yamamoto
Yoshihiko Koga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Application granted granted Critical
Publication of CA1062616A publication Critical patent/CA1062616A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CA253,859A 1975-06-02 1976-06-01 Analgetic composition containing an indole-3-acetic acid derivative Expired CA1062616A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/582,757 US4029798A (en) 1975-06-02 1975-06-02 Analgetic composition

Publications (1)

Publication Number Publication Date
CA1062616A true CA1062616A (en) 1979-09-18

Family

ID=24330416

Family Applications (1)

Application Number Title Priority Date Filing Date
CA253,859A Expired CA1062616A (en) 1975-06-02 1976-06-01 Analgetic composition containing an indole-3-acetic acid derivative

Country Status (9)

Country Link
US (2) US4029798A (US20100012521A1-20100121-C00001.png)
JP (1) JPS51142544A (US20100012521A1-20100121-C00001.png)
BE (1) BE842440A (US20100012521A1-20100121-C00001.png)
CA (1) CA1062616A (US20100012521A1-20100121-C00001.png)
FR (1) FR2313045A1 (US20100012521A1-20100121-C00001.png)
GB (1) GB1513646A (US20100012521A1-20100121-C00001.png)
IL (1) IL49695A (US20100012521A1-20100121-C00001.png)
NL (1) NL7605322A (US20100012521A1-20100121-C00001.png)
ZA (1) ZA763211B (US20100012521A1-20100121-C00001.png)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237140A (en) * 1979-05-18 1980-12-02 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and acetaminophen
SU975016A1 (ru) * 1979-12-17 1982-11-23 Московский научно-исследовательский онкологический институт им.П.А.Герцена Болеутол ющее средство
CH643138A5 (de) * 1983-08-29 1984-05-30 Mepha Ag Indomethacin enthaltende, gelartige salbe.
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
US4599342A (en) * 1984-01-16 1986-07-08 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
US7501433B2 (en) * 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7923454B2 (en) * 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
EP1506174B1 (en) 2002-05-17 2015-09-30 Taiwanj Pharmaceuticals Co., Ltd. Use of naltrexone for treating kidney and liver damage
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT290523B (de) * 1962-01-05 1971-06-11 Merck & Co Inc Verfahren zur Herstellung neuer α-(3-Indolyl)-carbonsäuren
US3250678A (en) * 1963-01-16 1966-05-10 Sterling Drug Inc Analgesia producing benzazocines
US3576800A (en) * 1966-01-12 1971-04-27 Sumitomo Chemical Co 1-acyl-3-indolyl aliphatic acid derivatives and their method of preparation
US3551446A (en) * 1967-06-08 1970-12-29 Sumitomo Chemical Co 1-aryloxyalkylcarbonyl-3-indolyl aliphatic acid derivatives
US3833595A (en) * 1968-12-26 1974-09-03 Sumitomo Chemical Co 2-aroylalkyl benzomorphans
HU163443B (US20100012521A1-20100121-C00001.png) * 1970-08-26 1973-08-28
HU166378B (US20100012521A1-20100121-C00001.png) * 1972-12-19 1975-03-28
US4027024A (en) * 1972-12-19 1977-05-31 Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt Pharmaceutical composition having synergistic analgesic activity

Also Published As

Publication number Publication date
JPS5330787B2 (US20100012521A1-20100121-C00001.png) 1978-08-29
FR2313045B1 (US20100012521A1-20100121-C00001.png) 1978-11-17
JPS51142544A (en) 1976-12-08
ZA763211B (en) 1977-05-25
AU1442776A (en) 1977-07-14
US4029798A (en) 1977-06-14
IL49695A (en) 1978-12-17
US4083981A (en) 1978-04-11
NL7605322A (nl) 1976-12-06
GB1513646A (en) 1978-06-07
BE842440A (fr) 1976-10-01
IL49695A0 (en) 1976-09-30
FR2313045A1 (fr) 1976-12-31

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